2022
Glaucoma Genetic Risk Scores in the Million Veteran Program
Waksmunski A, Kinzy T, Cruz L, Nealon C, Halladay C, Simpson P, Canania R, Anthony S, Roncone D, Rogers L, Leber J, Dougherty J, Greenberg P, Sullivan J, Wu W, Iyengar S, Crawford D, Peachey N, Bailey J, Gaziano J, Ramoni R, Breeling J, Chang K, Huang G, Muralidhar S, O’Donnell C, Tsao P, Muralidhar S, Moser J, Whitbourne S, Brewer J, Concato J, Warren S, Argyres D, Tsao P, Stephens B, Brophy M, Humphries D, Do N, Shayan S, Nguyen X, O’Donnell C, Pyarajan S, Cho K, Pyarajan S, Hauser E, Sun Y, Zhao H, Wilson P, McArdle R, Dellitalia L, Harley J, Whittle J, Beckham J, Wells J, Gutierrez S, Gibson G, Kaminsky L, Villareal G, Kinlay S, Xu J, Hamner M, Haddock K, Bhushan S, Iruvanti P, Godschalk M, Ballas Z, Buford M, Mastorides S, Klein J, Ratcliffe N, Florez H, Swann A, Murdoch M, Sriram P, Yeh S, Washburn R, Jhala D, Aguayo S, Cohen D, Sharma S, Callaghan J, Oursler K, Whooley M, Ahuja S, Gutierrez A, Schifman R, Greco J, Rauchman M, Servatius R, Oehlert M, Wallbom A, Fernando R, Morgan T, Stapley T, Sherman S, Anderson G, Tsao P, Sonel E, Boyko E, Meyer L, Gupta S, Fayad J, Hung A, Lichy J, Hurley R, Robey B, Striker R. Glaucoma Genetic Risk Scores in the Million Veteran Program. Ophthalmology 2022, 129: 1263-1274. PMID: 35718050, PMCID: PMC9997524, DOI: 10.1016/j.ophtha.2022.06.012.Peer-Reviewed Original ResearchConceptsPrimary open-angle glaucomaInvasive glaucoma surgeryRisk stratificationMillion Veteran ProgramEffect estimatesPOAG casesEuropean ancestryOpen-angle glaucomaCross-sectional studyDegenerative eye diseasesAfrican ancestryVeteran ProgramGenetic risk scoreAggressive treatmentGlaucoma surgeryEarly treatmentIrreversible blindnessEye diseaseHigh riskRisk scoreIncremental riskVisual impairmentGenetic riskVeteransRisk variants
2017
T45 Genetic Factor Common To Schizophrenia And Hiv Infection Is Associated With Risky Sexual Behavior
Wang Q, Polimanti R, Kranzler H, Farrer L, Zhao H, Gelernter J. T45 Genetic Factor Common To Schizophrenia And Hiv Infection Is Associated With Risky Sexual Behavior. European Neuropsychopharmacology 2017, 27: s460-s461. DOI: 10.1016/j.euroneuro.2016.09.533.Peer-Reviewed Original ResearchRisky sexual behaviorBody mass indexHIV infectionPolygenic risk scoresRisk scoreSexual behaviorHuman immunodeficiency virus (HIV) infectionSame effect directionImmunodeficiency virus infectionSZ-polygenic risk scoreGenetic risk factorsGenetic risk scoreSemi-Structured AssessmentMass indexRisk factorsEpidemiologic correlationsVirus infectionObservational studySynaptic transmissionHIVBipolar disorderNerve impulse transmissionSerious disorderDrug dependenceInfection