Cell membrane permeabilization via connexin hemichannels in living and dying cells
Sáez J, Schalper K, Retamal M, Orellana J, Shoji K, Bennett M. Cell membrane permeabilization via connexin hemichannels in living and dying cells. Experimental Cell Research 2010, 316: 2377-2389. PMID: 20595004, DOI: 10.1016/j.yexcr.2010.05.026.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DeathCell Membrane PermeabilityCell SurvivalConnexinsHumansIon Channel GatingIon ChannelsModels, BiologicalProtein BindingStructure-Activity RelationshipConceptsCell membrane permeabilityMembrane permeabilityComplex signaling cascadesConnexin hemichannelsDiverse cell typesCx HCsGap junction channelsVertebrate cellsCell membrane permeabilizationForm hemichannelsMembrane permeabilizationSignaling cascadesOpen probabilityJunction channelsCell typesCultured cellsExtracellular microenvironmentCell membraneHemichannelsMost cellsLow open probabilityStage dependencyUnitary conductanceSmall moleculesConnexins