1997
PEG-hemoglobin: effects on tumor oxygenation and response to chemotherapy.
Teicher B, Ara G, Herbst R, Takeuchi H, Keyes S, Northey D. PEG-hemoglobin: effects on tumor oxygenation and response to chemotherapy. In Vivo 1997, 11: 301-11. PMID: 9292296.Peer-Reviewed Original ResearchConceptsPEG-hemoglobinTumor growth delayMammary carcinomaTumor cell killingSolid tumorsTumor oxygenationGrowth delayDose of chemotherapyEMT-6 murine mammary carcinomaBone marrow CFU-GMEfficacy of chemotherapyEMT-6 tumorsMurine mammary carcinomaTumor-bearing miceCFU-GM survivalMarrow CFU-GMCell killingOxygen delivery agentEMT-6 tumor-bearing miceChemotherapy administrationLung metastasesMultiple dosesSingle dosesChemotherapyCFU-GM
1996
Lisofylline as a modifier of radiation therapy.
Wong J, Ara G, Keyes S, Herbst R, Coleman C, Teicher B. Lisofylline as a modifier of radiation therapy. Oncology Research Featuring Preclinical And Clinical Cancer Therapeutics 1996, 8: 513-8. PMID: 9160355.Peer-Reviewed Original ResearchConceptsEMT-6 cellsHypoxic EMT-6 cellsGy/minDose rate radiationTumor growth delay assayRate radiationEMT-6 murine mammary carcinomaSingle-dose radiationGrowth delay assayMurine mammary carcinomaHigh dose rate radiationLow dose rate radiationGamma radiation therapyRadiation survival curvesTumor cell survivalContinuous infusionMultiple dosesMammary carcinomaRadiation therapyPentoxifyllineLisofyllineRadiation settingsSurvival curvesDose radiationRadiation exposure