2019
Brain Metastasis From Renal-Cell Carcinoma: An Institutional Study
Suarez-Sarmiento A, Nguyen KA, Syed JS, Nolte A, Ghabili K, Cheng M, Liu S, Chiang V, Kluger H, Hurwitz M, Shuch B. Brain Metastasis From Renal-Cell Carcinoma: An Institutional Study. Clinical Genitourinary Cancer 2019, 17: e1163-e1170. PMID: 31519468, DOI: 10.1016/j.clgc.2019.08.006.Peer-Reviewed Original ResearchConceptsRCC brain metastasesRecurrence-free survivalRenal cell carcinomaBrain metastasesOverall survivalClinical trialsAdvanced renal cell carcinomaCentral nervous system treatmentClear cell renal cell carcinomaMedian overall survivalSingle institution experienceGood local controlKaplan-Meier methodAggressive therapyCNS recurrenceTreatment eraCumulative incidenceExtracranial metastasesMetastatic diseaseSystemic therapyInitial presentationLocal therapyClinical symptomsRCC patientsCell carcinoma
2018
Quality of life outcomes for brain metastasis patients treated with stereotactic radiosurgery: pre-procedural predictive factors from a prospective national registry.
Sheehan JP, Grills I, Chiang VL, Dong H, Berg A, Warnick RE, Kondziolka D, Kavanagh B. Quality of life outcomes for brain metastasis patients treated with stereotactic radiosurgery: pre-procedural predictive factors from a prospective national registry. Journal Of Neurosurgery 2018, 131: 1848-1854. PMID: 30579284, DOI: 10.3171/2018.8.jns181599.Peer-Reviewed Original ResearchConceptsQuality of lifeBrain metastasis patientsBrain metastasesStereotactic radiosurgeryMetastasis patientsEarly stereotactic radiosurgeryPre-procedural factorsProspective national registryPain/discomfortKarnofsky Performance Scale statusAnxiety/depressionMultivariate linear regression modelRadiological responseInitial presentationPatients' qualityMale sexPredictive factorsNational registryTreatment attributesMedical treatmentPatientsMetastasisSubscoresLife outcomesLife factors