2023
Use of stereotactic radiosurgery in treatment of brain metastases from pediatric extracranial solid tumors
Xu S, Campbell A, Chiang V, Bindra R, Vasquez J, Pashankar F. Use of stereotactic radiosurgery in treatment of brain metastases from pediatric extracranial solid tumors. Pediatric Blood & Cancer 2023, 70: e30303. PMID: 36975152, DOI: 10.1002/pbc.30303.Peer-Reviewed Original Research
2022
Real-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery
Petersen G, Bousabarah K, Verma T, von Reppert M, Jekel L, Gordem A, Jang B, Merkaj S, Fadel S, Owens R, Omuro A, Chiang V, Ikuta I, Lin M, Aboian MS. Real-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery. Neuro-Oncology Advances 2022, 4: vdac116. PMID: 36043121, PMCID: PMC9412827, DOI: 10.1093/noajnl/vdac116.Peer-Reviewed Original ResearchGamma KnifeTreatment responseBrain metastasis patientsFurther treatment planningNumber of lesionsMean followBrain metastasesMetastasis patientsMultiple lesionsDiagnostic followSingle patientStereotactic radiosurgeryPatientsLesionsIndividual lesionsPrevalenceAccurate surveillanceHeterogenous responseTreatment planningTreatmentFollowRadiosurgerySize assessmentComprehensive assessmentResponse
2021
Recognition and Management of Adverse Radiation Effects
Cheok S, Hansen J, Chiang V. Recognition and Management of Adverse Radiation Effects. 2021, 391-404. DOI: 10.1201/9781003167464-36.ChaptersAdverse radiation effectsRadiation necrosisStereotactic radiosurgeryRole of SRSImmune-mediated componentLaser interstitial thermotherapyMore brain lesionsBrain metastasesSystemic therapyIntracranial pathologyMalignant pathologyBrain lesionsNecrosisInterstitial thermotherapyPathologyContemporary evidenceBevacizumabCraniotomyMetastasisTherapyLesionsRadiosurgerySteroidsSURG-02. Stereotactic Laser Ablation (SLA) followed by consolidation stereotactic radiosurgery (SRS) as a treatment strategy for brain metastasis that recurred locally after initial radiosurgery (BMRS): a collaborative institutional experience
Pena-Pino I, Ma J, Hori Y, Fomchenko E, Dusenbery K, Reynolds M, Wilke C, Yuan J, Barnett G, Chiang V, Mohammadi A, Chen C. SURG-02. Stereotactic Laser Ablation (SLA) followed by consolidation stereotactic radiosurgery (SRS) as a treatment strategy for brain metastasis that recurred locally after initial radiosurgery (BMRS): a collaborative institutional experience. Neuro-Oncology Advances 2021, 3: iii23-iii23. PMCID: PMC8351296, DOI: 10.1093/noajnl/vdab071.095.Peer-Reviewed Original ResearchStereotactic laser ablationStereotactic radiosurgeryOverall survivalTreatment strategiesLocal controlDays of SRSSymptomatic radiation necrosisMedian overall survivalSystemic disease progressionRepeat stereotactic radiosurgeryIndependent clinical trialsInitial radiosurgerySteroid therapyBrain metastasesClinical outcomesRadiation necrosisFavorable outcomeClinical trialsDisease progressionFLAIR volumeInstitutional experiencePatientsCE volumeRadiosurgeryLocal failure
2020
Outcomes Of Stereotactic Radiosurgery And Immunotherapy In Renal Cell Carcinoma With Brain Metastases
Uezono H, Nam D, Yu J, Chiang V. Outcomes Of Stereotactic Radiosurgery And Immunotherapy In Renal Cell Carcinoma With Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e734. DOI: 10.1016/j.ijrobp.2020.07.133.Peer-Reviewed Original ResearchRadiation Necrosis Following the Radiosurgical Treatment of Brain Metastases
Robert S, Chiang V. Radiation Necrosis Following the Radiosurgical Treatment of Brain Metastases. 2020, 393-405. DOI: 10.1007/978-3-030-42958-4_28.ChaptersMetastatic brain lesionsRadiation necrosisBrain lesionsStereotactic radiosurgeryRadiation-induced side effectsImmune system involvementEffective treatment modalityMetastatic intracranial tumorsBrain metastasesSystemic cancerTreatment modalitiesUnderlying pathophysiologySystem involvementDisease entityIntracranial tumorsRadiosurgical treatmentSide effectsTumor progressionBrain tissueNecrosisConcurrent useLesionsRadiosurgeryImaging modalitiesLife expectancy
2019
Combining Radiosurgery and Systemic Therapies for Treatment of Brain Metastases
Chiang V, Cheok S. Combining Radiosurgery and Systemic Therapies for Treatment of Brain Metastases. 2019, 247-258. DOI: 10.1007/978-3-030-23417-1_19.Peer-Reviewed Original ResearchAdverse Radiation Effects
Cheok SK, Chiang VL. Adverse Radiation Effects. Progress In Neurological Surgery 2019, 34: 138-148. PMID: 31096237, DOI: 10.1159/000493058.Peer-Reviewed Original Research
2018
Salvage Stereotactic Radiosurgery is Associated with Improved Overall Survival Compared to Whole Brain Radiation in the Setting of Progressive Brain Metastases
Soike M, McTyre E, Farris M, Ayala-Peacock D, Hepel J, Page B, Kleinberg L, Contessa J, Chiang V, Cramer C, Ruiz J, Pasche B, Tatter S, Fiveash J, Ahluwalia M, Chao S, Braunstein S, Attia A, Chan M. Salvage Stereotactic Radiosurgery is Associated with Improved Overall Survival Compared to Whole Brain Radiation in the Setting of Progressive Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: s144. DOI: 10.1016/j.ijrobp.2018.06.350.Peer-Reviewed Original ResearchA Pilot/Phase II Study of Stereotactic Radiosurgery for Brain Metastases Using Rational Dose Selection
Yu J, Singh C, Bindra R, Contessa J, Husain Z, Hansen J, Park H, Roberts K, Bond J, Tien C, Guo F, Colaco R, Housri N, Magnuson W, Omay B, Chiang V. A Pilot/Phase II Study of Stereotactic Radiosurgery for Brain Metastases Using Rational Dose Selection. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e372-e373. DOI: 10.1016/j.ijrobp.2018.07.1113.Peer-Reviewed Original Research
2017
Stereotactic Radiosurgery for Trigeminal Neuralgia in Patients with Multiple Sclerosis: A Multicenter Study
Xu Z, Mathieu D, Heroux F, Abbassy M, Barnett G, Mohammadi A, Kano H, Caruso J, Grills I, Lee K, Krishnan S, Kaufmann A, Lee J, Pierce J, Maloney E, Kondziolka D, Hess J, Chiang V, Lunsford L, Sheehan J. Stereotactic Radiosurgery for Trigeminal Neuralgia in Patients with Multiple Sclerosis: A Multicenter Study. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: s186-s187. DOI: 10.1016/j.ijrobp.2017.06.465.Peer-Reviewed Original Research
2016
Novel biomarker identification using metabolomic profiling to differentiate radiation necrosis and recurrent tumor following Gamma Knife radiosurgery.
Lu AY, Turban JL, Damisah EC, Li J, Alomari AK, Eid T, Vortmeyer AO, Chiang VL. Novel biomarker identification using metabolomic profiling to differentiate radiation necrosis and recurrent tumor following Gamma Knife radiosurgery. Journal Of Neurosurgery 2016, 127: 388-396. PMID: 27885954, DOI: 10.3171/2016.8.jns161395.Peer-Reviewed Original ResearchConceptsGamma knife radiosurgeryRadiation necrosisRecurrent tumorsKnife radiosurgeryBrain metastasesSamples of tumorMetabolic imaging techniquesMetabolite profilesUnique metabolite profilesNovel biomarker identificationBrain biopsyPure tumorEnhancing lesionsSurgical biopsyLevels of metabolitesTumorsNecrosisTumor samplesDifferential metabolite profilesElevated levelsRadiosurgeryNoninvasive imagingComparison groupTissue samplesMetabolomic profilingReply to timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery
Yu JB, Chiang VL. Reply to timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery. Cancer 2016, 122: 3577-3578. PMID: 27495789, DOI: 10.1002/cncr.30243.Peer-Reviewed Original Research
2015
Surgery in neuro-oncolgy with a focus on stereotactic radiosurgery
Chiang V. Surgery in neuro-oncolgy with a focus on stereotactic radiosurgery. CNS Oncology 2015, 4: 199-201. PMID: 26118857, PMCID: PMC6088336, DOI: 10.2217/cns.15.18.Peer-Reviewed Original Research
2014
BM-10SYSTEMIC TREATMENT AND RADIATION NECROSIS FOLLOWING GKSRS IN THE TREATMENT OF BRAIN METASTASES
Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. BM-10SYSTEMIC TREATMENT AND RADIATION NECROSIS FOLLOWING GKSRS IN THE TREATMENT OF BRAIN METASTASES. Neuro-Oncology 2014, 16: v34-v34. PMCID: PMC4217910, DOI: 10.1093/neuonc/nou240.10.Peer-Reviewed Original ResearchSystemic Treatment and Radiation Necrosis Following Gamma Knife Radiosurgery in the Treatment of Brain Metastases
Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. Systemic Treatment and Radiation Necrosis Following Gamma Knife Radiosurgery in the Treatment of Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s310. DOI: 10.1016/j.ijrobp.2014.05.1035.Peer-Reviewed Original Research
2013
Secondary Neoplasms After Stereotactic Radiosurgery
Patel TR, Chiang VL. Secondary Neoplasms After Stereotactic Radiosurgery. World Neurosurgery 2013, 81: 594-599. PMID: 24148883, DOI: 10.1016/j.wneu.2013.10.043.Peer-Reviewed Original ResearchConceptsStereotactic radiosurgerySecondary neoplasmsCentral nervous system diseaseLong-term surveillance imagingNervous system diseasesRadiation-induced neoplasmsLong-term riskInitial diagnosisSurveillance imagingVestibular schwannomaTreatment paradigmSubsequent riskSystem diseasesNeoplasmsMedical radiationRadiation exposureRadiosurgeryRiskPatientsSchwannomaYearsDiseaseDiagnosis
2012
Tracking Metastatic Brain Tumors in Longitudinal Scans via Joint Image Registration and Labeling
Chitphakdithai N, Chiang VL, Duncan JS. Tracking Metastatic Brain Tumors in Longitudinal Scans via Joint Image Registration and Labeling. Lecture Notes In Computer Science 2012, 7570: 124-136. PMID: 31187098, PMCID: PMC6559745, DOI: 10.1007/978-3-642-33555-6_11.Peer-Reviewed Original Research
2011
Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update
Park HS, Chiang VL, Knisely JP, Raldow AC, Yu JB. Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update. Expert Review Of Anticancer Therapy 2011, 11: 1731-1738. PMID: 22050022, DOI: 10.1586/era.11.165.Peer-Reviewed Original ResearchConceptsWhole-brain radiation therapyStereotactic radiosurgeryBrain metastasesAddition of SRSUse of SRSMD Anderson Cancer CenterWhole brain radiotherapyLocal tumor controlStandard of careAnderson Cancer CenterNormal brain tissueNonrandomized evidenceLimited metastasesOligometastatic diseaseCancer CenterTumor controlRelative sparingRadiation therapyBrain tissueMetastasisSingle fractionNormal tissuesPatientsRadiosurgeryTrialsA Comprehensive Review of MR Imaging Changes following Radiosurgery to 500 Brain Metastases
Patel TR, McHugh BJ, Bi WL, Minja FJ, Knisely JP, Chiang VL. A Comprehensive Review of MR Imaging Changes following Radiosurgery to 500 Brain Metastases. American Journal Of Neuroradiology 2011, 32: 1885-1892. PMID: 21920854, PMCID: PMC7966021, DOI: 10.3174/ajnr.a2668.Peer-Reviewed Original ResearchConceptsBrain metastasesMedian survivalMetastatic lesionsLesion sizeMost metastatic lesionsMR imaging changesPercent of lesionsInitial treatment volumeSystemic cancer therapyInitial lesion sizeIntracranial metastatic lesionsGK-SRSLesional responsePatient demographicsRadiographic responseInitial treatmentImaging changesMale sexTumor sizeLesion volumeStereotactic radiosurgeryTreatment dosePatientsLesionsRadiosurgery