2015
Post-radiosurgical edema associated with parasagittal and parafalcine meningiomas: a multicenter study
Sheehan JP, Cohen-Inbar O, Ruangkanchanasetr R, Bulent Omay S, Hess J, Chiang V, Iorio-Morin C, Alonso-Basanta M, Mathieu D, Grills IS, Lee JY, Lee CC, Dade Lunsford L. Post-radiosurgical edema associated with parasagittal and parafalcine meningiomas: a multicenter study. Journal Of Neuro-Oncology 2015, 125: 317-324. PMID: 26329323, DOI: 10.1007/s11060-015-1911-1.Peer-Reviewed Original ResearchConceptsStereotactic radiosurgeryParafalcine meningiomaTumor controlTumor volumeInternational Gamma Knife Research FoundationPost-surgical residual tumorAdjuvant stereotactic radiosurgeryRetrospective multicenter reviewTumor volume controlUpfront stereotactic radiosurgeryVenous sinus compressionMedian marginal doseMedian tumor volumeSubset of patientsLong-term followPeri-tumoral edemaExtent of edemaVenous sinus invasionMedian followMarginal doseMulticenter reviewPrognostic factorsSinus compressionResidual tumorMulticenter study
2014
Significance of histology in determining management of lesions regrowing after radiosurgery
Nath SK, Sheridan AD, Rauch PJ, Yu JB, Minja FJ, Vortmeyer AO, Chiang VL. Significance of histology in determining management of lesions regrowing after radiosurgery. Journal Of Neuro-Oncology 2014, 117: 303-310. PMID: 24504499, DOI: 10.1007/s11060-014-1389-2.Peer-Reviewed Original ResearchConceptsBrain metastasesTumor cellsLocal controlSignificance of histologyWorse local controlResidual tumor cellsPost-treatment imagingManagement of lesionsOngoing patient managementInflammatory changesClinical outcomesResidual tumorSymptomatic enlargementAmbiguous etiologyHistologic findingsPatient outcomesPatient managementBrain specimensStereotactic radiosurgeryHistopathologic interpretationLesionsTissue specimensResectionPatientsMetastasis