Development of a Model of Hemispheric Hypodensity (âBig Black Brainâ)
Costine-Bartell B, McGuone D, Price G, Crawford E, Keeley K, Munoz-Pareja J, Dodge CP, Staley K, Duhaime AC. Development of a Model of Hemispheric Hypodensity (âBig Black Brainâ). Journal Of Neurotrauma 2018, 36: 815-833. PMID: 30039743, PMCID: PMC6387571, DOI: 10.1089/neu.2018.5736.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain Injuries, TraumaticDisease Models, AnimalHematoma, Subdural, IntracranialSwineConceptsHemispheric hypodensitySubdural hematomaAbusive head traumaMultiple vascular territoriesMechanism of traumaSevere brain damagePatterns of injuryDeep gray matterSeizure durationHead traumaMultiple injuriesPathological examinationKainic acidSevere seizuresVasogenic edemaBrain damageContralateral sideVascular territoriesCommon findingMetabolic mismatchRelative sparingAnimal modelsRadiological indicatorsCortical ribbonGray matter
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