2024
High-Grade Transformation and Carcinosarcoma: A Review of Two Forms of Advanced Progression in the Salivary Gland.
Verma A, Seethala R, Wang H. High-Grade Transformation and Carcinosarcoma: A Review of Two Forms of Advanced Progression in the Salivary Gland. Archives Of Pathology & Laboratory Medicine 2024, 148: 1196-1208. PMID: 38569599, DOI: 10.5858/arpa.2023-0534-ra.Peer-Reviewed Original ResearchConceptsHigh-grade transformationSalivary gland carcinomasPleomorphic adenomaSalivary glandsImmunophenotypic featuresClinical presentationHigh-grade areasMitotic countCellular atypiaCarcinosarcomaDiagnostic criteriaPrognosisRare phenomenonLiterature searchRelevant articlesCarcinomaAdenomasMolecular featuresMolecular characteristicsGlandDedifferentiationAdvanced progressAtypia
2019
Salivary Gland
Jiang H, Arbzadeh E, Gong Y, Wang H. Salivary Gland. Practical Anatomic Pathology 2019, 225-244. DOI: 10.1007/978-3-030-24059-2_14.Peer-Reviewed Original ResearchSalivary gland tumorsFine-needle aspirationGland tumorsSalivary Gland CytopathologyCytomorphological featuresCystic lesionsDifferential diagnosisFNA diagnosisAncillary testsWorld Health Organization classificationPrimary salivary gland tumorsSalivary glandsTissue microarray studyAdequate tissue samplingMilan SystemSufficient diagnostic materialSalivary gland lesionsSalivary gland massesPatient ageClinical symptomsHistological typeOrganization classificationCommon subtypeMetastatic tumorsNeck surgeons
2016
FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases
Wang H, Hoda R, Faquin W, Rossi E, Hotchandani N, Sun T, Pusztaszeri M, Bizzarro T, Bongiovanni M, Patel V, Jhala N, Fadda G, Gong Y. FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases. Cancer Cytopathology 2016, 125: 91-103. PMID: 28001329, DOI: 10.1002/cncy.21798.Peer-Reviewed Original ResearchConceptsFine-needle aspiration biopsySquamous cell carcinomaDefinitive diagnosisDiagnostic challengeMetastatic squamous cell carcinomaDefinitive malignant diagnosisMean patient ageSalivary glandsCommon malignant neoplasmFalse-negative diagnosesPatient ageSecondary malignanciesMetastatic carcinomaCell carcinomaPathology databaseMalignant neoplasmsFNAB diagnosisFNAB casesMalignant diagnosisMetastatic chordomaAncillary studiesNasopharyngeal carcinomaAspiration biopsyAncillary testsOlder menFusion proteins in head and neck neoplasms: Clinical implications, genetics, and future directions for targeting
Escalante D, Wang H, Fundakowski C. Fusion proteins in head and neck neoplasms: Clinical implications, genetics, and future directions for targeting. Cancer Biology & Therapy 2016, 17: 995-1002. PMID: 27636353, PMCID: PMC5079396, DOI: 10.1080/15384047.2016.1219823.Peer-Reviewed Original ResearchNeck neoplasmsClinical implicationsTyrosine kinase inhibitor dasatinibCell lung cancerTreatment of headChronic myeloid leukemiaBCR-ABL fusionKinase inhibitor dasatinibLung cancerNovel fusion proteinHematologic malignanciesMyeloid leukemiaMidline headSolid neoplasmsDiagnostic targetingNeoplasmsInhibitor dasatinibFusion proteinDiagnostic opportunitiesBiological behaviorSalivary glandsTherapeutic triumphsNeck structuresMalignancyPathogenesis
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