2020
Cytologic grading of primary malignant salivary gland tumors: A blinded review by an international panel
Johnson DN, Onenerk M, Krane JF, Rossi ED, Baloch Z, Barkan G, Bongiovanni M, Callegari F, Canberk S, Dixon G, Field A, Griffith CC, Jhala N, Jiang S, Kurtycz D, Layfield L, Lin O, Maleki Z, Perez‐Machado M, Pusztaszeri M, Vielh P, Wang H, Zarka MA, Faquin WC. Cytologic grading of primary malignant salivary gland tumors: A blinded review by an international panel. Cancer Cytopathology 2020, 128: 392-402. PMID: 32267606, PMCID: PMC7413070, DOI: 10.1002/cncy.22271.Peer-Reviewed Original ResearchConceptsSalivary gland carcinomasFine-needle aspirationPrimary salivary gland carcinomaSalivary gland tumorsTumor gradeMedical CenterSGC casesGland tumorsPrimary malignant salivary gland tumorsHigh-grade salivary gland carcinomasMalignant salivary gland tumorsTertiary medical centerSalivary duct carcinomaCorresponding resection specimensAcinic cell carcinomaEpithelial-myoepithelial carcinomaAcademic medical centerSalivary gland fine-needle aspirationPreoperative evaluationStudy cohortDuct carcinomaCell carcinomaHistologic diagnosisHistopathologic examinationInternational panel
2019
Primary salivary gland‐type tumors of the tracheobronchial tree diagnosed by transbronchial fine needle aspiration: Clinical and cytomorphologic features with histopathologic correlation
Doxtader EE, Shah AA, Zhang Y, Wang H, Dyhdalo KS, Farver C. Primary salivary gland‐type tumors of the tracheobronchial tree diagnosed by transbronchial fine needle aspiration: Clinical and cytomorphologic features with histopathologic correlation. Diagnostic Cytopathology 2019, 47: 1168-1176. PMID: 31343850, DOI: 10.1002/dc.24285.Peer-Reviewed Original ResearchConceptsSalivary gland-type tumorsTransbronchial fine needle aspirationPrimary salivary gland-type tumorsFine-needle aspirationTracheobronchial treeSalivary gland tumorsNeedle aspirationCytomorphologic featuresGland tumorsSalivary gland-type neoplasmsPrimary salivary gland tumorsSurgical pathology specimenClear cell carcinomaCorresponding surgical specimenAdenoid cystic carcinomaEpithelial-myoepithelial carcinomaSurgical pathology specimensSalivary gland typeEndobronchial biopsyFrequent diagnosisStudy cohortLung massTracheal massCell carcinomaCytomorphologic changesApplication of the Milan System for Reporting Submandibular Gland Cytopathology: An international, multi‐institutional study
Maleki Z, Baloch Z, Lu R, Shafique K, Song SJ, Viswanathan K, Rao RA, Lefler H, Fatima A, Wiles A, Jo VY, Wang H, Fadda G, Powers CN, Ali SZ, Pantanowitz L, Siddiqui MT, Nayar R, Klijanienko J, Barkan GA, Krane JF, Rossi ED, Callegari F, Kholová I, Bongiovanni M, Faquin WC, Pusztaszeri MP. Application of the Milan System for Reporting Submandibular Gland Cytopathology: An international, multi‐institutional study. Cancer Cytopathology 2019, 127: 306-315. PMID: 31050186, PMCID: PMC7404554, DOI: 10.1002/cncy.22135.Peer-Reviewed Original ResearchAdolescentAdultAgedAged, 80 and overAlgorithmsBiopsy, Fine-NeedleChildChild, PreschoolCytodiagnosisFemaleFollow-Up StudiesHealth FacilitiesHumansInfantInternational AgenciesMaleMedical RecordsMiddle AgedPrecancerous ConditionsRetrospective StudiesRisk AssessmentSalivary Gland NeoplasmsSubmandibular GlandYoung Adult
2018
Moving Toward a Systematic Approach for Reporting Salivary Gland Cytopathology: An Institutional Experience and Literature Review
Luo X, Jhala N, Khurana JS, Fundakowski C, Jhala DN, Wang H. Moving Toward a Systematic Approach for Reporting Salivary Gland Cytopathology: An Institutional Experience and Literature Review. Archives Of Pathology & Laboratory Medicine 2018, 143: 664-669. PMID: 30044125, DOI: 10.5858/arpa.2017-0283-ra.Peer-Reviewed Original Research
2017
“Suspicious” salivary gland FNA: Risk of malignancy and interinstitutional variability
Maleki Z, Miller JA, Arab SE, Fadda G, Bo P, Wise O, Rossi ED, Jhala N, Ashish C, Ali SZ, Wang H. “Suspicious” salivary gland FNA: Risk of malignancy and interinstitutional variability. Cancer Cytopathology 2017, 126: 94-100. PMID: 29053216, DOI: 10.1002/cncy.21939.Peer-Reviewed Original ResearchConceptsRisk of malignancySalivary gland FNAsFNA specimensExact testSuspicious casesFine needle aspiration cytologyEpithelial metaplastic changesSignificant interinstitutional variabilityTertiary medical centerFisher's exact testSalivary gland neoplasmsSalivary gland lesionsSFM categoryMetaplastic changesMalignancy categoryConclusive diagnosisMalignant tumorsAspiration cytologyMedical CenterFNA casesIndeterminate resultsSFM groupGland neoplasmsSpecific neoplasmsGland lesions“Atypical” salivary gland fine needle aspiration: Risk of malignancy and interinstitutional variability
Wang H, Malik A, Maleki Z, Rossi ED, Ping B, Chandra A, Ali SZ, Fadda G, Wang J, Arab SE, Zhao H, Jhala N. “Atypical” salivary gland fine needle aspiration: Risk of malignancy and interinstitutional variability. Diagnostic Cytopathology 2017, 45: 1088-1094. PMID: 28960946, DOI: 10.1002/dc.23826.Peer-Reviewed Original ResearchConceptsRisk of malignancyFine-needle aspirationSalivary gland fine-needle aspirationMalignant tumorsNeedle aspirationTertiary medical centerSalivary gland lesionsHistological resectionSalivary Gland CytopathologyBenign tumorsMedical CenterAtypical diagnosisBenign neoplasmsBenign lesionsFNA yieldGland lesionsInterinstitutional variabilityDiagnostic categoriesMorphologic heterogeneityDiagnosisTumorsMilan SystemVariable practiceMalignancyLesions
2016
FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases
Wang H, Hoda R, Faquin W, Rossi E, Hotchandani N, Sun T, Pusztaszeri M, Bizzarro T, Bongiovanni M, Patel V, Jhala N, Fadda G, Gong Y. FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases. Cancer Cytopathology 2016, 125: 91-103. PMID: 28001329, DOI: 10.1002/cncy.21798.Peer-Reviewed Original ResearchConceptsFine-needle aspiration biopsySquamous cell carcinomaDefinitive diagnosisDiagnostic challengeMetastatic squamous cell carcinomaDefinitive malignant diagnosisMean patient ageSalivary glandsCommon malignant neoplasmFalse-negative diagnosesPatient ageSecondary malignanciesMetastatic carcinomaCell carcinomaPathology databaseMalignant neoplasmsFNAB diagnosisFNAB casesMalignant diagnosisMetastatic chordomaAncillary studiesNasopharyngeal carcinomaAspiration biopsyAncillary testsOlder men
2015
Fine-Needle Aspiration Biopsy of Salivary Gland Lesions
Wang H, Fundakowski C, Khurana J, Jhala N. Fine-Needle Aspiration Biopsy of Salivary Gland Lesions. Archives Of Pathology & Laboratory Medicine 2015, 139: 1491-7. PMID: 26619021, DOI: 10.5858/arpa.2015-0222-ra.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, PleomorphicBiomarkers, TumorBiopsy, Fine-NeedleCarcinomaClinical Decision-MakingHumansSalivary Gland NeoplasmsSalivary GlandsConceptsFine-needle aspirationSalivary gland neoplasmsSalivary gland lesionsGland neoplasmsGland lesionsFNA samplesPersonal practice experiencePreoperative patient counselingNeedle aspiration biopsySalivary gland tumorsClinical decision makingSalivary gland fine-needle aspirationPatient counselingNovel classification systemImmunohistochemical markersAspiration biopsyGland tumorsMolecular pathogenesisNew classification systemDiagnostic approach
2014
Fine‐needle aspiration biopsy of secondary neoplasms of the thyroid gland: A multi‐institutional study of 62 cases
Pusztaszeri M, Wang H, Cibas ES, Powers CN, Bongiovanni M, Ali S, Khurana KK, Michaels PJ, Faquin WC. Fine‐needle aspiration biopsy of secondary neoplasms of the thyroid gland: A multi‐institutional study of 62 cases. Cancer Cytopathology 2014, 123: 19-29. PMID: 25369542, DOI: 10.1002/cncy.21494.Peer-Reviewed Original ResearchConceptsFine-needle aspiration biopsySquamous cell carcinomaThyroid fine-needle aspiration biopsySecondary neoplasmsAncillary studiesAspiration biopsyThyroid glandAccuracy of FNABMean patient ageMean tumor sizeUnknown primary siteUseful ancillary studiesMulti-institutional studyPatient ageInitial diagnosisTumor sizeCell carcinomaClinical historyPrimary tumorMedical recordsDiagnostic difficultiesMean intervalCystic carcinomaPrimary siteAdenocarcinomaLearning curve for endobronchial ultrasound-guided transbronchial needle aspiration: Experience of a community-based teaching hospital
WANG H, D’CRUZ C, YAM D, DILLA L, TSANG P. Learning curve for endobronchial ultrasound-guided transbronchial needle aspiration: Experience of a community-based teaching hospital. Molecular Medicine Reports 2014, 10: 2441-2446. PMID: 25189939, DOI: 10.3892/mmr.2014.2533.Peer-Reviewed Original ResearchConceptsEndobronchial ultrasound-guided transbronchial needle aspirationUltrasound-guided transbronchial needle aspirationTransbronchial needle aspirationEBUS-TBNACell blocksTissue diagnosisNeedle aspirationHistological examinationTTF-1Community-based teaching hospitalAcid-fast bacilli stainMetastatic lung carcinomaSquamous cell carcinomaThyroid transcription factor-1KRAS mutation analysisSubsequent tissue diagnosisSufficient diagnostic materialCell block preparationsLymph nodesMetastatic adenocarcinomaMediastinal lymphomaCell carcinomaNodal stagingLung cancerTranscription factor 1