2021
Clinical characteristics and outcomes of splenic infarction in cancer patients: a retrospective, single center report of 206 cases
Bewersdorf JP, Parmar N, Israel GM, Gettinger SN, Lee AI. Clinical characteristics and outcomes of splenic infarction in cancer patients: a retrospective, single center report of 206 cases. Journal Of Thrombosis And Thrombolysis 2021, 52: 854-862. PMID: 33765243, DOI: 10.1007/s11239-021-02428-0.Peer-Reviewed Original ResearchConceptsAtrial fibrillation/flutterSplenic infarctCancer patientsThromboembolic eventsRisk factorsHigh riskExact testMultivariable logistic regression modelYale-New Haven HospitalRetrospective cohort studyThromboembolic risk factorsUse of anticoagulationVenous thromboembolic eventsSingle-center reportsΧ2 testLow platelet countFisher's exact testNew Haven HospitalMultivariable regression modelsLow recurrence riskLogistic regression modelsPearson χ2 testAnticoagulation useClinical characteristicsCohort study
2020
Clinical Characteristics and Outcomes of Splenic Infarction in Cancer Patients - a Retrospective, Single Center Report of 206 Cases
Bewersdorf J, Parmar N, Gettinger S, Israel G, Lee A. Clinical Characteristics and Outcomes of Splenic Infarction in Cancer Patients - a Retrospective, Single Center Report of 206 Cases. Blood 2020, 136: 22-23. DOI: 10.1182/blood-2020-136646.Peer-Reviewed Original ResearchSubsequent venous thromboembolic eventsVenous thromboembolic eventsAtrial fibrillation/flutterMultivariable logistic regression modelSplenic infarctCancer ptsSplenic vasculatureLogistic regression modelsThromboembolic eventsVein thrombosisCancer patientsHigh riskExact testSingle-center case seriesBivariate analysisYale-New Haven HospitalBenefits of anticoagulationInitial cancer stagingRoutine cancer surveillancePortal vein thrombosisHistory of malignancySingle-center reportsΧ2 testAdditional prospective studiesDirect tumor invasionPatterns of care and clinical outcomes with cytarabine-anthracycline induction chemotherapy for AML patients in the United States
Zeidan AM, Podoltsev NA, Wang X, Zhang C, Bewersdorf JP, Shallis RM, Huntington SF, Neparidze N, Giri S, Gore SD, Davidoff AJ, Ma X, Wang R. Patterns of care and clinical outcomes with cytarabine-anthracycline induction chemotherapy for AML patients in the United States. Blood Advances 2020, 4: 1615-1623. PMID: 32311013, PMCID: PMC7189301, DOI: 10.1182/bloodadvances.2020001728.Peer-Reviewed Original ResearchConceptsIntensive induction chemotherapyAcute myeloid leukemiaHospital deathInduction chemotherapyAdult patientsMultivariable logistic regression modelLow hospital volumePremier Healthcare DatabasePredictors of deathHealthcare resource utilizationIntensive care unitPatterns of careStandard of careLogistic regression modelsFit patientsRemission inductionFirst hospitalizationHospital volumeInpatient deathInpatient mortalityOlder patientsSupportive careMedian ageAML patientsCare unit
2019
Temporal patterns and predictors of receiving no active treatment among older patients with acute myeloid leukemia in the United States: A population‐level analysis
Zeidan AM, Podoltsev NA, Wang X, Bewersdorf JP, Shallis RM, Huntington SF, Gore SD, Davidoff AJ, Ma X, Wang R. Temporal patterns and predictors of receiving no active treatment among older patients with acute myeloid leukemia in the United States: A population‐level analysis. Cancer 2019, 125: 4241-4251. PMID: 31483484, PMCID: PMC7733320, DOI: 10.1002/cncr.32439.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaTime of diagnosisOlder patientsActive treatmentMyeloid leukemiaMultivariable logistic regression modelMedian overall survivalPercentage of patientsLow-intensity therapyMajority of patientsNovel therapeutic optionsQuality of careLogistic regression modelsIntensity therapyTherapy receiptOverall survivalWorse survivalClinical factorsInferior survivalEntire cohortTherapeutic optionsPatient populationRetrospective analysisHigher oddsProvider characteristics