2024
Synthesis of αâQuaternary Amides via Cp*Co(III)-Catalyzed Sequential CâH Bond Addition to 1,3-Dienes and Isocyanates
Yeo J, Tassone J, Ellman J. Synthesis of αâQuaternary Amides via Cp*Co(III)-Catalyzed Sequential CâH Bond Addition to 1,3-Dienes and Isocyanates. Organic Letters 2024, 26: 9769-9774. PMID: 39481088, PMCID: PMC11578270, DOI: 10.1021/acs.orglett.4c03740.Peer-Reviewed Original ResearchSynthesis of Monodehydro-Diketopiperazines Enabled by Cp*Rh(III)-Catalyzed Amine-Directed NâH Functionalization
Molas J, Poag E, Ellman J. Synthesis of Monodehydro-Diketopiperazines Enabled by Cp*Rh(III)-Catalyzed Amine-Directed NâH Functionalization. Organic Letters 2024, 26: 8527-8531. PMID: 39332014, PMCID: PMC11512471, DOI: 10.1021/acs.orglett.4c03105.Peer-Reviewed Original ResearchRh(II)-Catalyzed Enantioselective SâAlkylation of Sulfenamides with AcceptorâAcceptor Diazo Compounds Enables the Synthesis of Sulfoximines Displaying Diverse Functionality
Patel S, Greenwood N, Mercado B, Ellman J. Rh(II)-Catalyzed Enantioselective SâAlkylation of Sulfenamides with AcceptorâAcceptor Diazo Compounds Enables the Synthesis of Sulfoximines Displaying Diverse Functionality. Organic Letters 2024, 26: 6295-6300. PMID: 39004842, PMCID: PMC11292377, DOI: 10.1021/acs.orglett.4c02402.Peer-Reviewed Original Research
2023
Synthesis of NâAcylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by OneâPot SulfurâArylation and Dealkylation
Greenwood N, Cerny N, Deziel A, Ellman J. Synthesis of NâAcylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by OneâPot SulfurâArylation and Dealkylation. Angewandte Chemie International Edition 2023, 63: e202315701. PMID: 38015869, PMCID: PMC10813656, DOI: 10.1002/anie.202315701.Peer-Reviewed Original ResearchS bond formationOne-pot approachBoronic acidsBond formationComplex bioactive compoundsComplex precursorSulfur functionalizationDiverse electrophilesSulfur groupsReaction conditionsDrug apixabanDrug precursorsS-substituentsThermal eliminationReaction inputConcerted eliminationMechanistic studiesBioactive compoundsSynthesisIodideBroad scopePrecursorsFunctionalizationCatalystAcidSynthesis of NâAcylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by OneâPot SulfurâArylation and Dealkylation
Greenwood N, Cerny N, Deziel A, Ellman J. Synthesis of NâAcylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by OneâPot SulfurâArylation and Dealkylation. Angewandte Chemie 2023, 136 DOI: 10.1002/ange.202315701.Peer-Reviewed Original ResearchOne-pot approachBoronic acidsBond formationComplex bioactive compoundsComplex precursorSulfur functionalizationDiverse electrophilesSulfur groupsReaction conditionsDrug apixabanDrug precursorsS-substituentsThermal eliminationReaction inputConcerted eliminationMechanistic studiesBioactive compoundsSynthesisIodideBroad scopePrecursorsFunctionalizationCatalystAcidStyrene
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