334 Whole Exome Sequencing of End Stage Renal Disease Associated Papillary Renal Cell Carcinoma (PRCCs)
Farooq T, Saeed F, Zhang D, Huang W, Yin C, Zhong M. 334 Whole Exome Sequencing of End Stage Renal Disease Associated Papillary Renal Cell Carcinoma (PRCCs). American Journal Of Clinical Pathology 2018, 149: s144-s144. DOI: 10.1093/ajcp/aqx127.333.Peer-Reviewed Original ResearchEnd-stage renal diseasePapillary renal cell carcinomaRenal cell carcinomaSporadic papillary renal cell carcinomasWhole-exome sequencingCell carcinomaExome sequencingSurgical pathology databaseSporadic renal cell carcinomaSpecific genetic alterationsParaffin-embedded tissuesGenomic DNARenal diseasePathology databaseCarcinomaProfile levelsGene mutationsGenetic mutationsGenetic alterationsFrequent mutationsMolecular changesSingle nucleotide variantsTargeted sequencingHuge overlapRNA kit344 Detection of ERG Rearrangement in Formalin-Fixed Paraffin-Embedded Tissue of Prostatic Adenocarcinoma by Targeted RNA-seq
Saeed F, Zhuge J, Huang W, Yang X, Volyanskyy K, Dimitrova N, Fallon J, Zhong M. 344 Detection of ERG Rearrangement in Formalin-Fixed Paraffin-Embedded Tissue of Prostatic Adenocarcinoma by Targeted RNA-seq. American Journal Of Clinical Pathology 2018, 149: s148-s148. DOI: 10.1093/ajcp/aqx127.343.Peer-Reviewed Original ResearchERG translocationProstate cancerProstatic adenocarcinomaTissue microarrayERG rearrangementErythroblast transformation-specific (ETS) transcription factorFusionPlex Solid Tumor KitAnchored multiplex PCRProstate cancer pathogenesisTMPRSS2-ERG fusion geneTMPRSS2-ERG fusionParaffin-embedded tissuesFrequent gene rearrangementsERG stainingIHC stainsNegative tissuesCancer pathogenesisGene rearrangementsRNA-seqTMA slidesAdenocarcinomaChromosomal translocationsFrequent eventCancerFusion gene