2017
Pursuit of Noncovalent Interactions for Strategic Site-Selective Catalysis
Toste FD, Sigman MS, Miller SJ. Pursuit of Noncovalent Interactions for Strategic Site-Selective Catalysis. Accounts Of Chemical Research 2017, 50: 609-615. PMID: 28945415, PMCID: PMC5643260, DOI: 10.1021/acs.accounts.6b00613.Peer-Reviewed Original Research
2015
Phosphothreonine as a Catalytic Residue in Peptide‐Mediated Asymmetric Transfer Hydrogenations of 8‐Aminoquinolines
Shugrue CR, Miller SJ. Phosphothreonine as a Catalytic Residue in Peptide‐Mediated Asymmetric Transfer Hydrogenations of 8‐Aminoquinolines. Angewandte Chemie International Edition 2015, 54: 11173-11176. PMID: 26246129, PMCID: PMC4628550, DOI: 10.1002/anie.201505898.Peer-Reviewed Original ResearchConceptsTransfer hydrogenationChiral phosphoric acid catalystHydrogen bonding interactionsPhosphoric acid catalystAsymmetric transfer hydrogenationEnantioselective transfer hydrogenationAsymmetric catalystsAcid catalystStrong complexationNMR studiesSubstrate classesCatalystHydrogenationNew classCatalytic residuesPeptidesComplexationEnantioselectivityQuinolinePhosphopeptidesSubstrateResidues