2016
Signal Transduction and Regulation: Insights into Evolution
Yi S, Chen S, Zhang L, Sahni N. Signal Transduction and Regulation: Insights into Evolution. BioMed Research International 2016, 2016: 8604245. PMID: 27525280, PMCID: PMC4971294, DOI: 10.1155/2016/8604245.Peer-Reviewed Original Research
2013
New Gene Evolution: Little Did We Know
Long M, VanKuren NW, Chen S, Vibranovski MD. New Gene Evolution: Little Did We Know. Annual Review Of Genetics 2013, 47: 307-333. PMID: 24050177, PMCID: PMC4281893, DOI: 10.1146/annurev-genet-111212-133301.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainDrosophila melanogasterEvolution, MolecularForecastingGene DosageGene DuplicationGene Expression RegulationGene Regulatory NetworksGene Transfer, HorizontalGenesGenes, InsectGenes, PlantGenetic StructuresHumansMammalsModels, GeneticPhenotypePhylogenyRecombination, GeneticRNA, UntranslatedSelection, GeneticSex CharacteristicsTranscription, GeneticConceptsNew gene originationNew genesGene originationGenetic systemNew gene evolutionNew gene structuresGene evolutionPhenotypic evolutionGene structureDifferent organismsBiological diversityPhenotypic functionsGenesGenomeOriginationEvolutionDecades of effortOrganismsDiversityComprehensive pictureCritical componentNew genes as drivers of phenotypic evolution
Chen S, Krinsky BH, Long M. New genes as drivers of phenotypic evolution. Nature Reviews Genetics 2013, 14: 645-660. PMID: 23949544, PMCID: PMC4236023, DOI: 10.1038/nrg3521.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBehavior, AnimalBiodiversityBiological EvolutionBrainEvolution, MolecularGene Expression RegulationGenesHumansPhenotypePlantsReproductionSex CharacteristicsSpecies SpecificityConceptsNew genesPhenotypic evolutionLineage-specific essential genesBiological processesUnexpected genetic diversityEvolution of phenotypesFundamental biological processesGene evolutionGenetic circuitryDrosophila sppEssential genesField of geneticsGenetic diversityGenetic systemBiological diversityMolecular explanationGenesIndispensable roleKey PointsThe studySpeciesDiversityEssential componentEvolutionMammalsCentral importance
2012
Reshaping of global gene expression networks and sex‐biased gene expression by integration of a young gene
Chen S, Ni X, Krinsky BH, Zhang YE, Vibranovski MD, White KP, Long M. Reshaping of global gene expression networks and sex‐biased gene expression by integration of a young gene. The EMBO Journal 2012, 31: 2798-2809. PMID: 22543869, PMCID: PMC3380208, DOI: 10.1038/emboj.2012.108.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDrosophilaEvolution, MolecularFertilityGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksConceptsSex-biased gene expressionNew genesGene expressionPre-existing genesCo-evolved interactionsGenomic binding profileNew gene networksComparative expression profilingOrgan expression patternsGene expression networksEssential biological processesDiverse taxaYoung genesExpression networksGene networksRelated speciesGenetic networksDownstream genesGenomic levelExpression profilingExpression patternsBiological processesGenesMale fecundityCAF40
2011
Highly Tissue Specific Expression of Sphinx Supports Its Male Courtship Related Role in Drosophila melanogaster
Chen Y, Dai H, Chen S, Zhang L, Long M. Highly Tissue Specific Expression of Sphinx Supports Its Male Courtship Related Role in Drosophila melanogaster. PLOS ONE 2011, 6: e18853. PMID: 21541324, PMCID: PMC3082539, DOI: 10.1371/journal.pone.0018853.Peer-Reviewed Original ResearchMeSH KeywordsAnimal StructuresAnimalsBase PairingBase SequenceBrainConserved SequenceCourtshipDrosophila melanogasterFemaleGene Expression ProfilingGene Expression RegulationGenome, InsectGreen Fluorescent ProteinsMaleMolecular Sequence DataMutationOrgan SpecificityPeripheral Nervous SystemPromoter Regions, GeneticRNA, UntranslatedSexual Behavior, AnimalTransformation, GeneticConceptsDrosophila melanogasterBp regionCourtship behaviorNon-coding RNA genesWhole genome expression profilingBp upstream regionTissue-specific expressionGenome expression profilingMale courtship behaviorMale accessory glandsMelanogaster subgroupDrosophila speciesD. virilisRNA genesGene categoriesProtein functionKnockout mutationsWing hairsMale courtshipTarget genesExpression profilingGFP signalNegative regulatorEnhancer elementsExpression signals