2000
The Use Of Isolated Limb Perfusion To Manage Recurrent Malignant Melanoma
Ma D, Ariyan S. The Use Of Isolated Limb Perfusion To Manage Recurrent Malignant Melanoma. Clinics In Plastic Surgery 2000, 27: 441-450. PMID: 10941564, DOI: 10.1016/s0094-1298(20)32739-5.Peer-Reviewed Original ResearchConceptsRecurrent malignant melanomaMalignant melanomaLimb perfusionTumor necrosis factor alphaRecurrent metastatic diseaseIsolated limb perfusionNecrosis factor alphaList of drugsHyperthermic ILPRecurrent diseaseMetastatic diseaseTumor loadLimb functionClinical trialsSurgical techniqueFactor alphaWound hygieneChemotherapeutic agentsMelanomaPerfusionDiseaseExtremitiesTreatmentHyperthermicTrials
1984
Regional isolated perfusion of high risk melanoma of the extremities with imidazole carboxamide.
Ariyan S, Mitchell M, Kirkwood J. Regional isolated perfusion of high risk melanoma of the extremities with imidazole carboxamide. Journal Of The American College Of Surgeons 1984, 158: 238-42. PMID: 6701736.Peer-Reviewed Original ResearchConceptsRegional isolated perfusionIntransit metastasesIsolated perfusionSerum glutamic-oxalacetic transaminase levelFirst postoperative dayGlutamic oxalacetic transaminase levelHigh-risk melanomaTransaminase levelsPostoperative daySubcutaneous metastasesFourth patientNew lesionsFifth patientRisk melanomaImidazole carboxamidePatientsPerfused extremitySymptoms of toxicityValuable drugMetastasisExtremitiesMelanomaPerfusionMonthsDecarbazine
1982
Intralymphatic and regional surgical adjuvant immunotherapy in high-risk melanoma of the extremities.
Ariyan S, Kirkwood J, Mitchell M, Nordlund J, Lerner A, Papac R. Intralymphatic and regional surgical adjuvant immunotherapy in high-risk melanoma of the extremities. Surgery 1982, 92: 459-63. PMID: 7112396.Peer-Reviewed Original ResearchConceptsBacillus Calmette-GuerinSurgical adjuvant immunotherapyMER-BCGAdjuvant immunotherapyControl groupHigh-risk malignant melanomaDisease-free survivalHigh-risk melanomaIntraoperative infiltrationImmunotherapy groupIntradermal vaccinationIntralymphatic immunotherapyRegional lymphadenectomyConsecutive patientsSurgical excisionCalmette-GuerinMalignant melanomaPatientsImmunotherapyMethanol-extractable residueLymphadenectomyRecurrenceMelanomaExtremitiesSame interval