Analysis of gene–environment interactions in postnatal development of the mammalian intestine
Rakoff-Nahoum S, Kong Y, Kleinstein SH, Subramanian S, Ahern PP, Gordon JI, Medzhitov R. Analysis of gene–environment interactions in postnatal development of the mammalian intestine. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: 1929-1936. PMID: 25691701, PMCID: PMC4343130, DOI: 10.1073/pnas.1424886112.Peer-Reviewed Original ResearchConceptsTLR/IL-1RToll-like receptorsPostnatal developmentIntestinal gene expressionMyeloid differentiation factor 88Domain-containing adapter-inducing interferonDifferentiation factor 88Adapter-inducing interferonMast cell homeostasisIntestinal ontogenyReceptor family membersFactor 88WT miceGene expression programsSmooth muscle developmentGene-environment interactionsIL-1RIntestinal physiologyImmune systemKnockout littermatesPostnatal transitionMicrobial colonizationIntestinal contentsGene expressionPubertal maturation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply