2020
A structured model for immune exposures
Vita R, Overton JA, Dunn P, Cheung KH, Kleinstein SH, Sette A, Peters B. A structured model for immune exposures. Database 2020, 2020: baaa016. PMID: 32283555, PMCID: PMC7153954, DOI: 10.1093/database/baaa016.Peer-Reviewed Original ResearchMeSH KeywordsAntibodiesAntigensBiological OntologiesComputational BiologyData CurationDatabases, FactualEpitopesHumansImmune SystemImmune System DiseasesConceptsImmune exposure
2015
Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases
Gorenshteyn D, Zaslavsky E, Fribourg M, Park CY, Wong AK, Tadych A, Hartmann BM, Albrecht RA, García-Sastre A, Kleinstein SH, Troyanskaya OG, Sealfon SC. Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases. Immunity 2015, 43: 605-614. PMID: 26362267, PMCID: PMC4753773, DOI: 10.1016/j.immuni.2015.08.014.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBayes TheoremComputational BiologyGene Regulatory NetworksHost-Pathogen InteractionsHumansImmune SystemImmune System DiseasesInternetProtein Interaction MappingProtein Interaction MapsReproducibility of ResultsSignal TransductionSupport Vector MachineTranscriptomeVirus DiseasesConceptsPublic high-throughput dataGenome-scale experimentsDisease-associated genesHigh-throughput datasetsHigh-throughput dataData-driven hypothesesGenetic studiesImmune pathwaysGenesImmunological diseasesFunctional relationshipBiomedical research effortsImportant interactionsMolecular entitiesImmune systemHuman immune systemProteinExponential growthPathwayData resourcesBayesian integrationRelevant insightsGrowthCompendiumIdentification