2024
Evaluation of the study of control arms in randomized clinical trials of cancer.
Jain S, Zauderer M, Sethi T, Schoen M, Rubinstein S, Nguyen R, Nagpal S, Mohan S, Madireddy S, Lythgoe M, Liang W, Kulkarni A, Kothari S, Hilal T, Hadfield M, Goyal G, Ganta T, Dholaria B, Brown A, Warner J. Evaluation of the study of control arms in randomized clinical trials of cancer. Journal Of Clinical Oncology 2024, 42: 11023-11023. DOI: 10.1200/jco.2024.42.16_suppl.11023.Peer-Reviewed Original ResearchRandomized clinical trialsSystemic anti-cancer therapyCancer randomized clinical trialsControl armSuccess rateClinical trials of cancerFisher's exact testAnti-cancer therapyTrial success ratesStudy publication yearExact testPatient convenienceRegimensClinical trialsHighest success rateExperimental armCancer typesCancerContext of treatmentPublication yearTrialsDoseNon-cancerEfficacyDyads
2020
Breakthrough concepts in immune-oncology: Cancer vaccines at the bedside
Roy S, Sethi TK, Taylor D, Kim YJ, Johnson DB. Breakthrough concepts in immune-oncology: Cancer vaccines at the bedside. Journal Of Leukocyte Biology 2020, 108: 1455-1489. PMID: 32557857, DOI: 10.1002/jlb.5bt0420-585rr.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMode of deliveryCancer vaccinesImmune checkpoint blockade agentsCheckpoint blockade agentsDifferent cancer vaccinesNeoantigen-based vaccinesRecent preclinical advancesCancer vaccine trialsCancer vaccine fieldLittle clinical activityPromising preclinical resultsMultiple cancer typesCheckpoint blockadeImmunotherapeutic trialsPreclinical advancesTherapeutic vaccinesVaccine trialsClinical activityPreclinical resultsClinical strategiesTherapeutic outcomesVaccine fieldClinical effortsVaccineCancer types