Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogram
Ayala-Peacock DN, Attia A, Braunstein SE, Ahluwalia MS, Hepel J, Chung C, Contessa J, McTyre E, Peiffer AM, Lucas JT, Isom S, Pajewski NM, Kotecha R, Stavas MJ, Page BR, Kleinberg L, Shen C, Taylor RB, Onyeuku NE, Hyde AT, Gorovets D, Chao ST, Corso C, Ruiz J, Watabe K, Tatter SB, Zadeh G, Chiang VLS, Fiveash JB, Chan MD. Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogram. Journal Of Neuro-Oncology 2017, 135: 403-411. PMID: 28828698, PMCID: PMC5667906, DOI: 10.1007/s11060-017-2588-4.Peer-Reviewed Original ResearchConceptsDistant brain failureWhole brain radiotherapyNew brain metastasesBrain metastasesStereotactic radiosurgeryRisk of DBFEarly whole brain radiotherapyPrognostic modelUpfront whole brain radiotherapyMulti-institutional nomogramNumber of metastasesHigh-risk thresholdSRS monotherapyMargin doseBrain radiotherapyBrain failureContemporary cohortPrognostic indexMelanoma histologyRelative riskAcademic centersMetastasisPatientsValidation datasetAbsolute number
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