Genomics, Genetics, & Epigenetics

GGE studies include:

• The discovery of mutations in genes and DNA that cause cancer
• Analysis of genomic changes and their functional consequences on gene expression
• Characterization of mechanisms that control protein production from genes
• Epigenetics
• Protein structure
• Analysis of large-scale genomic data

The goals of the GGE Program are to:

1. Identify and characterize the function of genetic alterations and epigenetic changes that contribute to cancer development and progression.
2. Develop new analytical tools, data resources, and novel laboratory models that enable better characterization and understanding of the cancer genome.
3. Translate genomic observations into clinically useful diagnostic and prognostic tests, and develop new therapies that exploit genetic and epigenetic alterations in cancer.