2016
Proposing prognostic thresholds for lymph node yield in clinically lymph node‐negative and lymph node‐positive cancers of the oral cavity
Kuo P, Mehra S, Sosa JA, Roman SA, Husain ZA, Burtness BA, Tate JP, Yarbrough WG, Judson BL. Proposing prognostic thresholds for lymph node yield in clinically lymph node‐negative and lymph node‐positive cancers of the oral cavity. Cancer 2016, 122: 3624-3631. PMID: 27479645, DOI: 10.1002/cncr.30227.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseOral cavity cancerMortality hazard ratioLymph nodesHazard ratioNeck dissectionLymph node-negative cancersLymph node-positive cancersNode-positive cancersNode-positive cohortPositive lymph nodesTherapeutic neck dissectionEnd Results (SEER) databaseLymph node yieldHigh-volume centersExtensive neck dissectionMultiple cancer sitesNode-negative cancersOverall survivalHigher lymphPrognostic factorsTreatment guidelinesNode yieldResults databaseSurgical management
2015
Predictors of Survival in Sinonasal Adenocarcinoma
Chen MM, Roman SA, Sosa JA, Judson BL. Predictors of Survival in Sinonasal Adenocarcinoma. Journal Of Neurological Surgery Part B Skull Base 2015, 76: 208-213. PMID: 26225303, PMCID: PMC4433397, DOI: 10.1055/s-0034-1543995.Peer-Reviewed Original ResearchDisease-specific survivalSinonasal adenocarcinomaAdjuvant radiationEnd Results (SEER) databasePredictors of survivalIntestinal-type histologyParanasal sinus involvementMain outcome measuresNonintestinal typeAdult patientsDSS ratesPostoperative radiationFavorable prognosisRetrospective reviewSinus involvementSurveillance EpidemiologyResults databaseType histologyBlack raceOutcome measuresAdenocarcinomaSurgeryPatientsHigh gradePrognosis
2014
Hypopharyngeal cancer incidence, treatment, and survival: Temporal trends in the United States
Kuo P, Chen MM, Decker RH, Yarbrough WG, Judson BL. Hypopharyngeal cancer incidence, treatment, and survival: Temporal trends in the United States. The Laryngoscope 2014, 124: 2064-2069. PMID: 25295351, DOI: 10.1002/lary.24651.Peer-Reviewed Original ResearchConceptsAverage annual percent changeHypopharyngeal cancerPatient demographicsTreatment modalitiesDisease severityEnd Results (SEER) databaseRetrospective cohort studyKaplan-Meier analysisAnnual percent changeAdult patientsCohort studyOverall survivalWorse survivalImproved survivalResults databaseT stageTumor characteristicsCox regressionCancer incidenceMultivariate analysisPercent changeLaryngopharyngectomyCancerIncidenceTemporal trendsPredictors of survival in carcinoma ex pleomorphic adenoma
Chen MM, Roman SA, Sosa JA, Judson BL. Predictors of survival in carcinoma ex pleomorphic adenoma. Head & Neck 2014, 36: 1324-1328. PMID: 23956034, DOI: 10.1002/hed.23453.Peer-Reviewed Original ResearchConceptsDisease-specific survivalCervical lymph node metastasisLymph node metastasisCa ex-PAPleomorphic adenomaLymph nodesNode metastasisMultiple cervical lymph node metastasesMultiple metastatic lymph nodesPositive lymph nodesEnd Results (SEER) databaseMetastatic lymph nodesPredictors of survivalHigh-grade carcinomaCarcinoma ex pleomorphic adenomaEx pleomorphic adenomaFirst population-level analysisBenign pleomorphic adenomaExtraparenchymal extensionCervical metastasisIndependent predictorsDistant metastasisPrognostic featuresResults databasePoor prognosisPrognostic factors for squamous cell cancer of the parotid gland: An analysis of 2104 patients
Chen MM, Roman SA, Sosa JA, Judson BL. Prognostic factors for squamous cell cancer of the parotid gland: An analysis of 2104 patients. Head & Neck 2014, 37: 1-7. PMID: 24339135, DOI: 10.1002/hed.23566.Peer-Reviewed Original ResearchConceptsSquamous cell cancerCell cancerRadiation therapyCutaneous squamous cell cancerCommon parotid malignancyAdjuvant radiation therapyDisease-specific mortalityDisease-specific survivalEnd Results (SEER) databaseYears of ageExtraparenchymal extensionCervical metastasisParotid malignanciesAdult patientsPrimary malignancyImproved survivalPrognostic factorsDistant metastasisResults databasePoor prognosisTumor sizeTreatment outcomesParotid glandPatientsSurgery
2013
Histologic grade as prognostic indicator for mucoepidermoid carcinoma: A population‐level analysis of 2400 patients
Chen MM, Roman SA, Sosa JA, Judson BL. Histologic grade as prognostic indicator for mucoepidermoid carcinoma: A population‐level analysis of 2400 patients. Head & Neck 2013, 36: 158-163. PMID: 23765800, DOI: 10.1002/hed.23256.Peer-Reviewed Original ResearchConceptsHigh-grade mucoepidermoid carcinomaDisease-specific survivalMucoepidermoid carcinomaNodal metastasisFive-year DSS ratesIntermediate-grade mucoepidermoid carcinomaEnd Results (SEER) databaseNegative prognostic factorParotid mucoepidermoid carcinomaHigh gradeFirst population-level studyExtraparenchymal extensionDSS ratesPatient ageUncommon malignancyPrognostic factorsDistant metastasisResults databaseTumor sizeHistologic gradePrognostic indicatorLevel IParotid glandMetastasisLarger studyRole of adjuvant radiation in patients with squamous cell carcinomas of the oral cavity.
Maron S, Gould Rothberg BE, Otremba M, Judson B, Morgensztern D. Role of adjuvant radiation in patients with squamous cell carcinomas of the oral cavity. Journal Of Clinical Oncology 2013, 31: 6042-6042. DOI: 10.1200/jco.2013.31.15_suppl.6042.Peer-Reviewed Original ResearchStage III squamous cell carcinomaSquamous cell carcinomaAdjuvant radiotherapyOral cavityCell carcinomaAddition of radiotherapyEnd Results (SEER) databaseLog-rank testingKaplan-Meier methodMultiple primary cancersOverall survival rateBenefits of radiotherapyCox proportional hazardsExtracapsular lymphStage T3N0T3N0 diseaseAdjuvant radiationImproved survivalSurveillance EpidemiologyInitial treatmentPrimary cancerResults databaseT3 diseaseEntire cohortProspective studyOutcomes for stage IVA squamous cell carcinoma of the oral cavity according to staging subtypes.
Marrone K, Otremba M, Groisberg R, Deshpande H, Crawford F, Acevedo-Gadea C, Gould Rothberg BE, Judson B, Morgensztern D. Outcomes for stage IVA squamous cell carcinoma of the oral cavity according to staging subtypes. Journal Of Clinical Oncology 2013, 31: 6076-6076. DOI: 10.1200/jco.2013.31.15_suppl.6076.Peer-Reviewed Original ResearchSquamous cell carcinomaStage IVAOverall survivalCell carcinomaOral cavityStage IVA squamous cell carcinomaIVA squamous cell carcinomaPatients meeting inclusion criteriaProportional hazards regression modelsLymph node categoryEnd Results (SEER) databaseLymph node statusKaplan-Meier methodLog-rank testHazards regression modelsMost clinical trialsCombination of tumorSubtypes of patientsMeeting inclusion criteriaSignificant differencesMost patientsIndependent predictorsNode statusResults databaseStage subgroups