2019
Radiation therapy treatment facility and overall survival in the adjuvant setting for locally advanced head and neck squamous cell carcinoma
Lee NCJ, Kelly JR, An Y, Park HS, Judson BL, Burtness BA, Husain ZA. Radiation therapy treatment facility and overall survival in the adjuvant setting for locally advanced head and neck squamous cell carcinoma. Cancer 2019, 125: 2018-2026. PMID: 30748002, PMCID: PMC6541535, DOI: 10.1002/cncr.32001.Peer-Reviewed Original ResearchConceptsHigh-volume surgical facilitiesPostoperative radiation therapyNeck squamous cell carcinomaSquamous cell carcinomaOverall survivalSurvival benefitCell carcinomaSurgical facilitiesPropensity score-matched cohortAnnual case volumeDefinitive surgeryAdvanced headOS improvementImproved outcomesRadiation therapyCase volumeOral cavityPatientsReduced hazardMultivariate analysisSurgeryInvasive HNSCCCarcinomaSurvivalTreatment
2018
Changing prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014
Cheraghlou S, Schettino A, Zogg CK, Judson BL. Changing prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014. The Laryngoscope 2018, 128: 2762-2769. PMID: 30194691, DOI: 10.1002/lary.27315.Peer-Reviewed Original ResearchConceptsOral cavity cancerLate-stage diseaseAdjuvant therapyOral cancerEnd Results 9 registriesCox survival regressionHigher nodal yieldsNational Cancer DatabaseEarly-stage diseaseKaplan-Meier analysisRetrospective database analysisAnalysis of survivalAdjuvant chemoradiotherapyNodal yieldAdult patientsNeck dissectionRetrospective studyCancer DatabasePrognosisPatientsCancerDiseaseDatabase analysisSurvival regressionChemoradiotherapyPatterns of failure in high-metastatic node number human papillomavirus-positive oropharyngeal carcinoma
Lee NCJ, Kelly JR, Park HS, An Y, Judson BL, Burtness BA, Husain ZA. Patterns of failure in high-metastatic node number human papillomavirus-positive oropharyngeal carcinoma. Oral Oncology 2018, 85: 35-39. PMID: 30220317, DOI: 10.1016/j.oraloncology.2018.08.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBrachytherapyCarcinoma, Squamous CellCombined Modality TherapyFemaleFollow-Up StudiesHumansLymphatic MetastasisMaleMiddle AgedNeck DissectionNeoplasm MetastasisNeoplasm Recurrence, LocalOropharyngeal NeoplasmsPapillomavirus InfectionsProgression-Free SurvivalProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesSalvage TherapyConceptsProgression-free survivalInvolved lymph nodesDistant metastasisPatterns of failureLocoregional recurrenceLymph nodesHuman papillomavirus-positive oropharyngeal carcinomaMultivariate analysisEdition American Joint CommitteeRate of DMWorse progression-free survivalHigh DM rateDedicated clinical trialsAmerican Joint CommitteeCancer (AJCC) staging systemProportional hazards regressionExternal beam radiationOropharynx cancerFree survivalNeck dissectionOropharyngeal carcinomaOverall survivalDisease recurrenceIntraoperative brachytherapyOPC patientsTreatment delays in laryngeal squamous cell carcinoma: A national cancer database analysis
Morse E, Fujiwara RJT, Judson B, Mehra S. Treatment delays in laryngeal squamous cell carcinoma: A national cancer database analysis. The Laryngoscope 2018, 128: 2751-2758. PMID: 29756382, DOI: 10.1002/lary.27247.Peer-Reviewed Original ResearchConceptsLaryngeal squamous cell carcinomaOverall survivalSquamous cell carcinomaTreatment initiationNonsurgical patientsSurgical patientsTotal treatment packageMedian durationRadiation treatmentTreatment delayCell carcinomaTreatment endNational Cancer Database AnalysisEnd intervalCox proportional hazards regressionNational Cancer DatabaseProportional hazards regressionMultivariable logistic regressionDuration of diagnosisHigh-volume facilitiesTreatment packageRadiotherapy durationAdjuvant treatmentHazards regressionInsurance status
2015
Refusal of postoperative radiotherapy and its association with survival in head and neck cancer
Schwam ZG, Husain Z, Judson BL. Refusal of postoperative radiotherapy and its association with survival in head and neck cancer. Radiotherapy And Oncology 2015, 117: 343-350. PMID: 26508285, DOI: 10.1016/j.radonc.2015.10.013.Peer-Reviewed Original ResearchConceptsNeck cancer patientsPostoperative radiotherapyPredictive factorsCancer patientsOverall survivalNegative nodesThree-year overall survivalCox proportional hazards analysisNational Cancer DatabaseProportional hazards analysisLong-term outcomesMultivariable logistic regressionSlow disease progressionCharlson scorePathologic variablesImproved survivalKaplan-MeierNeck cancerCancer DatabaseDisease progressionRetrospective analysisMultivariate analysisPatientsLogistic regressionSelect headComplications and mortality following surgery for oral cavity cancer: Analysis of 408 cases
Schwam ZG, Sosa JA, Roman S, Judson BL. Complications and mortality following surgery for oral cavity cancer: Analysis of 408 cases. The Laryngoscope 2015, 125: 1869-1873. PMID: 26063059, DOI: 10.1002/lary.25328.Peer-Reviewed Original ResearchConceptsOral cavity cancerPostdischarge complicationsPostoperative complicationsNeck dissectionNational Surgical Quality Improvement Program Participant Use Data FilesSurgeons National Surgical Quality Improvement Program Participant Use Data FilesSurgical siteDay 14Oral cavity cancer surgeryParticipant Use Data FilePostdischarge surgical-site infectionsCommon adverse eventsRetrospective cohort studySurgical site complicationsHigh-risk patientsModifiable risk factorsSurgical site infectionDisease-specific complicationsMultivariate regression analysisRespiratory complicationsAdverse eventsCohort studyCurrent smokersSite complicationsCancer surgery
2012
The Prognostic Importance of Midline Involvement in Oral Tongue Cancer
Lloyd S, Yu JB, Wilson LD, Judson BL, Decker RH. The Prognostic Importance of Midline Involvement in Oral Tongue Cancer. American Journal Of Clinical Oncology 2012, 35: 468-473. PMID: 21701377, PMCID: PMC3755371, DOI: 10.1097/coc.0b013e3182195619.Peer-Reviewed Original ResearchConceptsContralateral lymph node metastasisLymph node metastasisOral tongue squamous cell carcinomaTongue squamous cell carcinomaT2-3 diseaseSquamous cell carcinomaNode metastasisClinicopathologic factorsCell carcinomaMidline involvementEnd Results (SEER) dataLymph node statusOral tongue cancerDifferent prognostic classesLateral tumorsT4 tumorsT1 tumorsT3 tumorsT4 lesionsHistologic subtypeT3 lesionsNode statusPrognostic importanceT classificationTongue cancerPromoting Safe Swallowing When Puree is Swallowed Without Aspiration but Thin Liquid is Aspirated: Nectar is Enough
Leder SB, Judson BL, Sliwinski E, Madson L. Promoting Safe Swallowing When Puree is Swallowed Without Aspiration but Thin Liquid is Aspirated: Nectar is Enough. Dysphagia 2012, 28: 58-62. PMID: 22736260, DOI: 10.1007/s00455-012-9412-2.Peer-Reviewed Original ResearchConceptsSwallow testingSuccessful swallowingDysphagic patientsSafe swallowingThin liquidsTertiary care teaching hospitalThin liquid consistencyReferral-based sampleCommon compensatory strategyConsecutive inpatientsNeurological statusAspiration eventsOral alimentationStudy criteriaPatient preferencesPharyngeal dysphagiaSpecific subsetTeaching hospitalInclusion criteriaSwallow safetyPharyngeal swallowCare providersModified DietPatientsPuree consistency