2017
First Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery
Fischer S, Lee T, Krezdorn N, Alhefzi M, Kueckelhaus M, Bueno E, Pomahac B. First Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery. Plastic & Reconstructive Surgery 2017, 139: 1175e-1183e. PMID: 28445377, DOI: 10.1097/prs.0000000000003288.Peer-Reviewed Original ResearchConceptsFacial arteryFacial allograftImmunosuppressive therapyRejection episodesAirway volumeVenous outflowCLINICAL QUESTION/LEVELDual immunosuppressive therapyFacial allotransplantationTwo-thirdsMaintenance therapyMycophenolate mofetilSteroid pulseArtery anastomosisSurgical durationFacial functionTracheostomy tubeContralateral sideVascular anastomosisSubmental arteryTransplantationArteryAllograftsVascularization patternFacial form
2015
Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation
Kueckelhaus M, Turk M, Kumamaru K, Wo L, Bueno E, Lian C, Alhefzi M, Aycart M, Fischer S, De Girolami U, Murphy G, Rybicki F, Pomahac B. Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation. American Journal Of Transplantation 2015, 16: 968-978. PMID: 26639618, DOI: 10.1111/ajt.13544.Peer-Reviewed Original ResearchConceptsLong-term outcomesFacial allograftFacial allotransplantationSuperior long-term outcomesShort-term resultsRisk-benefit assessmentSoft tissue volumeSignificant volume lossTransplant recipientsVolume lossDiagnostic evaluationDonor selectionMuscle biopsyHistological evaluationComputed tomographyBone atrophyAllograftsFuture clinical routineNormal anatomyRecipient tissuesAllotransplantationClinical routineMorphometric changesSoft tissueMuscle fibersFacial transplantation
Wo L, Bueno E, Pomahac B. Facial transplantation. Current Opinion In Organ Transplantation 2015, Publish Ahead of Print: &na;. PMID: 26536422, DOI: 10.1097/mot.0000000000000253.Peer-Reviewed Original ResearchConceptsPositive HIV statusHIV statusFace transplantComposite allotransplantationUpper extremity transplantsDonor-specific antigensHistory of malignancyLatent viral infectionFacial transplantationChronic rejectionSimultaneous transplantationAbsolute contraindicationCase reportCurrent guidelinesFacial injuriesViral infectionTransplantTransplantationMedical teamAllotransplantationFirst face transplantFace transplantationFacial allotransplantationPatientsPsychological healthUtility of Sentinel Flaps in Assessing Facial Allograft Rejection
Kueckelhaus M, Fischer S, Lian C, Bueno E, Marty F, Tullius S, Pribaz J, Murphy G, Pomahac B. Utility of Sentinel Flaps in Assessing Facial Allograft Rejection. Plastic & Reconstructive Surgery 2015, 135: 250-258. PMID: 25255116, DOI: 10.1097/prs.0000000000000797.Peer-Reviewed Original ResearchConceptsFacial allograftRejection monitoringFasciocutaneous radial forearm flapCLINICAL QUESTION/LEVELSevere rejection episodesFurther surgical proceduresFacial allotransplantationFree fasciocutaneous radial forearm flapRadial forearm flapAxial blood supplyFunctional flapNonfacial sitesRejection episodesLimited skin areaSevere rejectionAllograft rejectionClinical findingsFacial dermatitisFrequent biopsiesBiopsy pairsBiopsy specimensHistologic evaluationSkin biopsiesBlood supplySurgical procedures
2013
Current Principles of Facial Allotransplantation
Pomahac B, Bueno E, Sisk G, Pribaz J. Current Principles of Facial Allotransplantation. Plastic & Reconstructive Surgery 2013, 131: 1069-1076. PMID: 23629089, PMCID: PMC4374342, DOI: 10.1097/prs.0b013e3182865cd3.Peer-Reviewed Original ResearchConceptsTransplant recipientsSurgical principlesFace transplant recipientsFacial allotransplantationFull screening procedureReturn of motorFace transplant candidatesFundamental surgical principlesTransplant candidatesTransplantation teamWomen's HospitalSevere casesSensory functionPatientsUnique caseAllotransplantationClinical volumeFacial disfigurementRecipientsHospitalScreening procedureFacial restorationCurrent principlesBrigham
2011
Restoration of Facial Form and Function After Severe Disfigurement from Burn Injury by a Composite Facial Allograft
Pomahac B, Pribaz J, Eriksson E, Annino D, Caterson S, Sampson C, Chun Y, Orgill D, Nowinski D, Tullius S. Restoration of Facial Form and Function After Severe Disfigurement from Burn Injury by a Composite Facial Allograft. American Journal Of Transplantation 2011, 11: 386-393. PMID: 21214855, DOI: 10.1111/j.1600-6143.2010.03368.x.Peer-Reviewed Original ResearchConceptsSevere disfigurementMedical historyBurn injuryFacial allograftAcute rejection episodesInitial clinical outcomesElectrical burn injuryFacial allotransplantationSevere facial disfigurementDonor's medical historyAntirejection treatmentRejection episodesPostoperative monthSurgical complicationsClinical outcomesNasal breathingTreatment optionsBolus treatmentPathological analysisMinimal doseNormal social lifeEsthetic resultsSignificant restorationFacial formFacial redness