2006
The value of onsite adequacy assessment of thyroid fine‐needle aspirations is a function of operator experience
Ghofrani M, Beckman D, Rimm DL. The value of onsite adequacy assessment of thyroid fine‐needle aspirations is a function of operator experience. Cancer 2006, 108: 110-113. PMID: 16400635, DOI: 10.1002/cncr.21715.Peer-Reviewed Original ResearchConceptsFine-needle aspirationThyroid fine-needle aspirationPalpation-guided fine-needle aspirationNondiagnostic rateOnsite evaluationUS guidancePerformance of FNAImmediate adequacy assessmentCurrent studyLower nondiagnostic rateFinal diagnosisChi-square analysisCytologic diagnosisNondiagnostic specimensNondiagnostic aspiratesPalpationSignificant decreaseDiagnosisImmediate evaluationExperienced radiologistsRadiologistsOperator experienceExperienced operatorsAdequate materialLess experience
2002
p53 Mutations as Tumor Markers in Fine Needle Aspirates of Palpable Breast Masses
Dillon DA, Hipolito E, Zheng K, Rimm DL, Costa JC. p53 Mutations as Tumor Markers in Fine Needle Aspirates of Palpable Breast Masses. Acta Cytologica 2002, 46: 841-847. PMID: 12365217, DOI: 10.1159/000327057.Peer-Reviewed Original ResearchMeSH KeywordsAbscessAdenocarcinomaAdultAgedAged, 80 and overAmino Acid SubstitutionBiomarkers, TumorBiopsy, NeedleBreast NeoplasmsCarcinoma, Ductal, BreastCodon, TerminatorCystsDNA Mutational AnalysisDNA, NeoplasmExonsFemaleFrameshift MutationGenes, p53GenotypeHumansMiddle AgedMutationPolymorphism, Single-Stranded ConformationalRetrospective StudiesConceptsFine needle aspiratesP53 exons 5Breast massesPolymerase chain reactionNeedle aspiratesP53 mutationsSingle-strand conformational polymorphism analysisSubsequent excisional biopsyPalpable breast massesPotential diagnostic utilityDefinitive cytologic diagnosisTumor cell markersExon 5Molecular diagnostic markersExcisional biopsyBenign cytologyBreast carcinomaSuspicious cytologyRetrospective analysisCytologic diagnosisTumor markersDiagnostic criteriaBiopsy tissueMorphologic diagnosisDiagnostic utility
2001
Use of magnetic enrichment for detection of carcinoma cells in fluid specimens
Kielhorn E, Schofield K, Rimm DL. Use of magnetic enrichment for detection of carcinoma cells in fluid specimens. Cancer 2001, 94: 205-211. PMID: 11815978, DOI: 10.1002/cncr.10193.Peer-Reviewed Original ResearchConceptsFluid specimensEpithelial cellsCarcinoma cellsCell enrichmentDetection of malignancyDetermination of malignancyRare epithelial cellsE-cadherin stainingPleural effusionAccurate stagingMetastatic carcinomaCytologic evaluationCytologic diagnosisMedical conditionsAtypical casesMalignant casesMalignant cellsInsufficient cellsNegative casesImmunomagnetic enrichmentAscites fluidMalignancyImmunomagnetic selectionCommon event
2000
The utility of Ki-ras mutation analysis in the cytologic diagnosis of pancreatobiliary neoplasma.
Dillon DA, Johnson CC, Topazian MD, Tallini G, Rimm DL, Costa JC. The utility of Ki-ras mutation analysis in the cytologic diagnosis of pancreatobiliary neoplasma. The Cancer Journal 2000, 6: 294-301. PMID: 11079168.Peer-Reviewed Original ResearchConceptsFine needle aspiratesBile duct brushingsCytologic diagnosisPositive predictive valueCommon bile duct brushingsDuct brushingsPancreatobiliary carcinomaPredictive valueMutation patternsBiliary tract carcinomaPrevious retrospective studyAvailable clinical informationConsecutive clinical specimensDefinitive cytologic diagnosisPolymerase chain reaction/single-strand conformation polymorphism analysisRoutine cytologic diagnosisPositive cytologyRetrospective studySuspicious morphologyCytologic evaluationSuspicious cytologyPancreatobiliary tractClinical informationMorphologic diagnosisNeoplastic cells
1997
Atypical squamous cells of undetermined significance: Correlative histologic and follow‐up studies from an academic medical center
Williams M, Rimm D, Pedigo M, Frable W. Atypical squamous cells of undetermined significance: Correlative histologic and follow‐up studies from an academic medical center. Diagnostic Cytopathology 1997, 16: 1-7. PMID: 9034728, DOI: 10.1002/(sici)1097-0339(199701)16:1<1::aid-dc2>3.0.co;2-m.Peer-Reviewed Original ResearchConceptsSquamous intraepithelial lesionsCervical intraepithelial neoplasiaCIN IICIN IIIIntraepithelial neoplasiaCytologic diagnosisHigh-grade cervical intraepithelial neoplasiaLow-grade cervical intraepithelial neoplasiaCervical intraepithelial neoplasia (CIN) IMild nuclear hyperchromasiaSubsequent colposcopic biopsyAtypical squamous cellsDiagnosis of ASCUSGroup of patientsIntraepithelial neoplasia IHigh-risk groupSubsequent cervical biopsyCases of carcinomaManagement of casesAcademic medical centerVirus cytopathic effectVaginal cytologic findingsEndocervical curettageColposcopic biopsyIntraepithelial lesions
1996
Atypical reparative change on cervical/vaginal smears may be associated with dysplasia
Rimm D, Gmitro S, Frable W. Atypical reparative change on cervical/vaginal smears may be associated with dysplasia. Diagnostic Cytopathology 1996, 14: 374-379. PMID: 8725141, DOI: 10.1002/(sici)1097-0339(199605)14:4<374::aid-dc17>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsHigh-grade squamous intraepithelial lesionsLow-grade squamous intraepithelial lesionsAtypical reparative changesDiagnosis of ASCUSSquamous intraepithelial lesionsReparative changesIntraepithelial lesionsAtypical repairVaginal smearsSignificant histologic abnormalitiesUniversity Pathology DepartmentAtypical squamous cellsPercentage of casesChronic cervicitisSquamous cellsSquamous metaplasiaHistologic abnormalitiesHistologic findingsClinical managementHistologic changesCytologic diagnosisBethesda SystemClinical concernPathology departmentMedical College