Featured Publications
Evolution of Surgical Management of Metastatic Disease of the Pelvis.
Benevenia J, Guinand LA, Ippolito J, Neilson JC, Fabbri N, Lee FY, Yang R, Kurland AM. Evolution of Surgical Management of Metastatic Disease of the Pelvis. Instructional Course Lectures 2022, 71: 185-201. PMID: 35254782.Peer-Reviewed Original ResearchConceptsSurgical managementSignificant pain reliefMetastatic bone diseaseRestoration of ambulationStandardized modalityPain reliefSevere painMetastatic diseasePostoperative periodSurgical treatmentMinimal complicationsSuccessful treatmentSurgical methodsSurgical reconstructionBone diseasePelvic lesionsInterventional methodsPatientsFrail stateMultidisciplinary approachDiseaseWound healingComplicationsLesionsLimited life spanEarly success of the arthroscopic-assisted locked loop suprapectoral biceps tenodesis
Kahan J, Schneble C, Applonie R, Nicholson A, Whittall I, Talley-Bruns R, Jorgensen A, LaVette N, Moran J, Ware J, Lee F, Blaine T. Early success of the arthroscopic-assisted locked loop suprapectoral biceps tenodesis. JSES Reviews Reports And Techniques 2021, 1: 96-101. PMID: 37588143, PMCID: PMC10426584, DOI: 10.1016/j.xrrt.2021.02.003.Peer-Reviewed Original ResearchBiceps tenodesisPostoperative complicationsPopeye deformityAnterior shoulderConcomitant operative proceduresSeries of patientsYears of ageSuprapectoral biceps tenodesisPrior biomechanical studiesTenodesis proceduresSingle surgeonSurgical indicationsMuscle crampingRevision surgeryTenodesis techniquesSurgical techniqueInclusion criteriaLower incidenceOperative procedureTenodesisPatientsPainSimple sutureBiomechanical studyComplications
2023
Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases
Jiang W, Caruana D, Dussik C, Conway D, Latich I, Chapiro J, Lindskog D, Friedlaender G, Lee F. Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases. Journal Of Clinical Medicine 2023, 12: 4613. PMID: 37510728, PMCID: PMC10380351, DOI: 10.3390/jcm12144613.Peer-Reviewed Original ResearchPercutaneous radiofrequency ablationBone mass changesCT scanMedian survivalHounsfield unitsOsteolytic metastasesRadiofrequency ablationBone massCancer-induced bone lossSuperior median survivalAvailable CT scansThree-dimensional volumetric analysisInternal screw fixationPeriacetabular areaPercutaneous stabilizationBone lossInternal fixationSingle institutionOrthopedic interventionsScrew fixationPatientsMonthsVolumetric analysisSurvivalScans
2020
Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus.
Samuel AM, Munger AM, Lee FY, Friedlaender GE, Ibe IK, Lindskog DM. Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus. Orthopedics 2020, 43: e498-e502. PMID: 32882054, DOI: 10.3928/01477447-20200827-05.Peer-Reviewed Original ResearchConceptsRadionuclide bone scanBone scanMRI scansPositive findingsNegative findingsMagnetic resonance imaging (MRI) scansBone scan findingsProgression of lesionsResonance imaging scansDiagnosis of enchondromaAcademic medical centerBivariate logistic regressionAssociation of boneScan findingsAggressive featuresRadiographic findingsEndosteal scallopingBenign enchondromaImaging scansMedical recordsMedical CenterMalignant lesionsCartilaginous lesionsEnchondromaPatientsAvoiding Limb-Length Discrepancy with Reconstruction of a Massive Tibial Defect Using a Bone Allograft and a Minimally Invasive Lengthening System in a Pediatric Patient: A Case Report.
Alder KD, Morris MT, Hao Z, Li L, Yu KE, Lee FY. Avoiding Limb-Length Discrepancy with Reconstruction of a Massive Tibial Defect Using a Bone Allograft and a Minimally Invasive Lengthening System in a Pediatric Patient: A Case Report. JBJS Case Connector 2020, 10: e0456. PMID: 32649132, DOI: 10.2106/jbjs.cc.19.00456.Peer-Reviewed Original Research
2019
Rotational Tibio-Pelvic Constrained Hip Arthroplasty: A Surgical Technique: A Case Report.
Cahill SV, Yu KE, Dussik CM, Lee FY. Rotational Tibio-Pelvic Constrained Hip Arthroplasty: A Surgical Technique: A Case Report. JBJS Case Connector 2019, 9: e0404. PMID: 31703012, DOI: 10.2106/jbjs.cc.18.00404.Peer-Reviewed Original ResearchConceptsSoft tissue infectionsVan Nes rotationplastyExtensive debridementChronic boneHip disarticulationTissue infectionsFemur resectionDebridement proceduresRecurrent infectionsCase reportRight thighEpithelioid sarcomaSurgical techniqueHip arthroplastyIncurable infectionProsthetic hipInfectionRotationplastyResectionMultiple revisionsProsthetic devicesDebridementPatientsSarcomaArthroplastyDefining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence
Munger AM, Geddes BJ, Lee FY. Defining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence. Journal Of Spine Surgery 2019, 5: 171-173. PMID: 31032452, PMCID: PMC6465459, DOI: 10.21037/jss.2019.03.04.Peer-Reviewed Original ResearchPharmacologic and Radiation Therapies for Cancer-Induced Bone Loss.
Henderson SE, Dussik C, Brand J, Ibe IK, Lee FY. Pharmacologic and Radiation Therapies for Cancer-Induced Bone Loss. Instructional Course Lectures 2019, 68: 557-566. PMID: 32032067.Peer-Reviewed Original ResearchMetastatic Cancers to Bone: An Overview and Cancer-Induced Bone Loss.
Ibe IK, Sahlstrom A, White A, Henderson SE, Lee FY. Metastatic Cancers to Bone: An Overview and Cancer-Induced Bone Loss. Instructional Course Lectures 2019, 68: 547-556. PMID: 32032068.Peer-Reviewed Original ResearchConceptsCancer-induced bone lossBone lossBone metastasesMetastatic bone diseaseCancer cellsDegree of osteolysisNormal bone homeostasisBenefit of patientsOsteolytic metastasesSkeletal metastasesPatient functionSurgical stabilizationWorse prognosisLocal bone massBone massMetastatic cancerBone diseaseRadiation therapyTherapeutic modalitiesBone homeostasisImmune systemOverall outcomeMetastasisBone remodelingPatients
2018
Immuno-oncologic Approach to Musculoskeletal Tumors
Ibe I, Sahlstrom A, Nguyen M, Lindskog D, Friedlaender G, Lee F. Immuno-oncologic Approach to Musculoskeletal Tumors. Techniques In Orthopaedics 2018, 33: 140-147. DOI: 10.1097/bto.0000000000000305.Peer-Reviewed Original ResearchImmune systemImmuno-oncologic therapiesSoft tissue sarcomasHost immune surveillanceActive immune responseTreatment of boneImmune therapyTumor burdenTissue sarcomasTreatment of cancerTreatment optionsMusculoskeletal tumorsComprehensive careImproved outcomesImmune surveillanceImmune responseOrthopedic oncologyMalignant cellsImmunotherapyCancer cellsPrecision medicineDistant sitesPatientsUnderlying mechanismTherapy
2010
Surmounting Chemotherapy and Radioresistance in Chondrosarcoma: Molecular Mechanisms and Therapeutic Targets
Onishi AC, Hincker AM, Lee FY. Surmounting Chemotherapy and Radioresistance in Chondrosarcoma: Molecular Mechanisms and Therapeutic Targets. Sarcoma 2010, 2011: 381564. PMID: 21234363, PMCID: PMC3018623, DOI: 10.1155/2011/381564.Peer-Reviewed Original ResearchNature of chemotherapyNew molecular targetsDirected therapyPrimary malignancySurgical resectionRadiation regimensCurative treatmentMolecular mechanismsSuccessful treatmentTherapeutic targetChemotherapyChondrosarcomaMolecular targetsTumorsTherapy researchTreatmentCurrent hypothesesResectionRegimensPatientsMalignancyTherapyDiagnosis
2006
The effect of limb length discrepancy on health-related quality of life: is the ‘2 cm rule’ appropriate?
Vitale MA, Choe JC, Sesko AM, Hyman JE, Lee FY, Roye DP, Vitale MG. The effect of limb length discrepancy on health-related quality of life: is the ‘2 cm rule’ appropriate? Journal Of Pediatric Orthopaedics B 2006, 15: 1-5. PMID: 16280711, DOI: 10.1097/01202412-200601000-00001.Peer-Reviewed Original Research
2005
Operative Lengthening of the Humerus
Lee FY, Schoeb JS, Yu J, Christiansen BD, Dick HM. Operative Lengthening of the Humerus. Journal Of Pediatric Orthopaedics 2005, 25: 613-616. PMID: 16199941, DOI: 10.1097/01.bpo.0000164868.97060.bb.Peer-Reviewed Original ResearchConceptsTemporary radial nerve palsyPosttraumatic growth disturbancesRadial nerve palsyUnicameral bone cystsElbow flexion contractureTime of lengtheningComplex neurovascular structuresImproved sports performanceHumeral lengtheningHumerus lengtheningOperative lengtheningNerve palsyMinor complicationsBone cystHumerus fracturesFlexion contractureMean ageCongenital anomaliesPin tractNeurovascular structuresPatientsAverage lengtheningComplicationsGrowth disturbanceDistraction osteogenesisPatient-Based Outcomes Following Clubfoot Surgery
Vitale MG, Choe JC, Vitale MA, Lee FY, Hyman JE, Roye DP. Patient-Based Outcomes Following Clubfoot Surgery. Journal Of Pediatric Orthopaedics 2005, 25: 533-538. PMID: 15958910, DOI: 10.1097/01.bpo.0000157999.38424.ba.Peer-Reviewed Original ResearchConceptsPatient-based measuresClubfoot surgeryChild Health QuestionnaireDisease-specific instrumentLong-term outcomesPatient-based outcomesDisease-specific measuresCohort of adolescentsQuality of lifePrimary endpointSurgical repairPractice patternsHealth QuestionnaireAppropriate treatmentAuthors' institutionRadiographic measuresHealth outcomesTreatment resultsHealthy feetYoung athletesPatientsSurgeryOutcomesOngoing controversySimilar resultsThe molecular pathophysiology of subacromial bursitis in rotator cuff disease
Blaine TA, Kim YS, Voloshin I, Chen D, Murakami K, Chang SS, Winchester R, Lee FY, O’Keefe R, Bigliani LU. The molecular pathophysiology of subacromial bursitis in rotator cuff disease. Journal Of Shoulder And Elbow Surgery 2005, 14: s84-s89. PMID: 15726092, DOI: 10.1016/j.jse.2004.09.022.Peer-Reviewed Original ResearchConceptsRotator cuff diseaseCuff diseaseSubacromial bursitisSubacromial bursaInstitutional review board-approved protocolAnti-inflammatory agentsExpression of metalloproteasesPresence of cytokinesSubacromial bursectomyShoulder surgerySubacromial impingementBiochemical pathophysiologyPatientsCytokine genesBursitisDiseaseMolecular pathophysiologyCyclooxygenaseGene expressionPattern of expressionInflammationPathophysiologyCytokinesMicroarray analysisFurther investigation
2004
Synovial Chondromatosis of the Foot
Lee F, Hornicek FJ, Dick HM, Mankin HJ. Synovial Chondromatosis of the Foot. Clinical Orthopaedics And Related Research® 2004, 423: 186-190. PMID: 15232447, DOI: 10.1097/01.blo.0000127133.89704.86.Peer-Reviewed Original ResearchEffect of bracing on the quality of life of adolescents with idiopathic scoliosis
Ugwonali OF, Lomas G, Choe JC, Hyman JE, Lee FY, Vitale MG, Roye DP. Effect of bracing on the quality of life of adolescents with idiopathic scoliosis. The Spine Journal 2004, 4: 254-260. PMID: 15125845, DOI: 10.1016/j.spinee.2003.12.001.Peer-Reviewed Original ResearchConceptsPediatric Outcomes Data Collection InstrumentChild Health QuestionnaireAdolescent idiopathic scoliosisQoL of adolescentsObserved patientsOrthopaedic Surgeons Pediatric Outcomes Data Collection InstrumentIdiopathic scoliosisTreatment of AISHealth-related qualityPresbyterian Medical CenterQuality of lifeAge-adjusted normsQuestionnaire-based studyAIS patientsHealth QuestionnaireStudy populationMedical CenterPatientsParents of adolescentsIndependent sample t-testQoLChildren's QoLMultivariate analysisAmerican AcademyTreatment type
2003
In Situ Pinning of Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Operating Table
Lee FY, Chapman CB. In Situ Pinning of Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Operating Table. Journal Of Pediatric Orthopaedics 2003, 23: 27. PMID: 12499938, DOI: 10.1097/01241398-200301000-00005.Peer-Reviewed Original ResearchConceptsCapital femoral epiphysisFracture tableFemoral epiphysisSitu pinningFrog-leg lateral radiographsStable Slipped Capital Femoral EpiphysisTime of diagnosisSlipped Capital Femoral EpiphysisPin entry pointRadiolucent operating tableObese patientsPercutaneous pinningAvascular necrosisLateral radiographsStable SCFEPatientsRadiolucent tableOperating tableHipSCFEEpiphysisIn Situ Pinning of Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Operating Table
Lee F, Chapman C. In Situ Pinning of Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Operating Table. Journal Of Pediatric Orthopaedics 2003, 23: 27-29. DOI: 10.1097/00004694-200301000-00005.Peer-Reviewed Original ResearchCapital femoral epiphysisFracture tableFemoral epiphysisSitu pinningFrog-leg lateral radiographsTime of diagnosisStable Slipped Capital Femoral EpiphysisSlipped Capital Femoral EpiphysisPin entry pointRadiolucent operating tableObese patientsPercutaneous pinningAvascular necrosisLateral radiographsPatientsRadiolucent tableStable SCFEOperating tableHipSCFE
2001
Coronal Split Fracture of the Proximal Tibia Epiphysis Through a Partially Closed Physis: A New Fracture Pattern
Patari S, Lee F, Behrens F. Coronal Split Fracture of the Proximal Tibia Epiphysis Through a Partially Closed Physis: A New Fracture Pattern. Journal Of Pediatric Orthopaedics 2001, 21: 451. PMID: 11433155, DOI: 10.1097/01241398-200107000-00007.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAdolescentBicyclingBiomechanical PhenomenaEpiphysesExternal FixatorsFollow-Up StudiesFracture Fixation, InternalFracture HealingFractures, ComminutedGaitHumansMaleRange of Motion, ArticularRisk FactorsTibial FracturesTomography, X-Ray ComputedTreatment OutcomeWeight-BearingConceptsCoronal split fractureProximal tibial epiphysisTibial epiphysisSplit fractureDefinitive operative fixationProximal tibia epiphysisNew fracture patternClinical unionUncommon injuryOperative fixationEpiphyseal fracturesPlain radiographyTibial plateauTibia epiphysisEpiphysisFracture patternsFracturesPatientsThree-dimensional reconstructionInjuryPhysis