Featured Publications
Percutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies.
Dussik C, Toombs C, Alder K, Yu K, Berson E, Ibe I, Li F, Lindskog D, Friedlaender G, Latich I, Lee F. Percutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies. Radiology 2023, 307: e221401. PMID: 36916888, DOI: 10.1148/radiol.221401.Peer-Reviewed Original ResearchMeSH KeywordsAgedCatheter AblationFemaleHumansMaleNeoplasmsOsteotomyQuality of LifeRetrospective StudiesTreatment OutcomeConceptsOsteolytic neoplasmAmbulatory functionInternal fixationEastern Cooperative Oncology Group scoreIndex scoreConversion hip arthroplastyRetrospective observational studySurgical site infectionKaplan-Meier analysisLong-term painQuality of lifeLong-term improvementWilcoxon signed-rank testNonambulatory patientsSecondary outcomesPrimary outcomeSite infectionOncologic careECOG scorePercutaneous ablationPeriacetabular metastasisProtrusio acetabuliFunctional improvementSigned-rank testClinical dataComparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck
Jiang W, Friedlaender G, Lindskog D, Latich I, Lee F. Comparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck. CardioVascular And Interventional Radiology 2023, 46: 649-657. PMID: 37052716, DOI: 10.1007/s00270-023-03425-x.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFemur HeadFracture Fixation, IntramedullaryHemiarthroplastyHumansMalePainRetrospective StudiesTreatment OutcomeConceptsOsteolytic lesionsFemoral headSurgical complicationsRevision proceduresLong intramedullary nailingResultsSixty-seven patientsPost-operative complicationsEffective alternative treatmentTraditional surgical approachesAmbulatory scoreCombined painPrimary outcomeMedical complicationsMetastatic lesionsOncologic careRetrospective studyIntramedullary nailingSurgical approachFunction scoresNeck lesionsEarly improvementIM groupHemiarthroplastyComparative efficacyAlternative treatmentEmerging Minimally Invasive Percutaneous Procedures for Periacetabular Osteolytic Metastases
Ibe I, Dussik C, Callan A, Barr J, Lee F. Emerging Minimally Invasive Percutaneous Procedures for Periacetabular Osteolytic Metastases. Journal Of Bone And Joint Surgery 2023, 105: 479-489. PMID: 36701566, DOI: 10.2106/jbjs.22.00694.Peer-Reviewed Original ResearchMeSH KeywordsBone CementsFracture Fixation, InternalHumansMinimally Invasive Surgical ProceduresNeoplasmsPolymethyl MethacrylateTreatment OutcomeConceptsInvasive percutaneous proceduresOsteolytic metastasesInvasive proceduresPercutaneous proceduresCancer ablationOsteolytic skeletal metastasesOpen surgical managementPercutaneous screw fixationSystemic cancer therapyOpen surgical proceduresRestoration of ambulationComplex open surgical proceduresPeriacetabular osteolytic lesionsBalloon osteoplastyAmbulatory functionTotal hip reconstructionBlood lossOsteolytic lesionsSkeletal metastasesSurgical managementInterventional oncologistsInternal fixationSurgical proceduresInvasive techniquesScrew fixationAblation, Osteoplasty, Reinforcement, and Internal Fixation for Percutaneous Endoskeletal Reconstruction of Periacetabular and Other Periarticular Osteolytic Metastases.
Toombs C, Conway D, Munger AM, Alder KD, Latich I, Lee FY. Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Percutaneous Endoskeletal Reconstruction of Periacetabular and Other Periarticular Osteolytic Metastases. Instructional Course Lectures 2021, 70: 503-514. PMID: 33438931.Peer-Reviewed Original ResearchMeSH KeywordsBone CementsBone NeoplasmsCementoplastyFracture Fixation, InternalHumansOsteolysisTreatment OutcomeConceptsInternal fixationLocal cancer controlBalloon osteoplastySurgical stabilizationCancer controlConventional open surgical proceduresLocal cancer progressionProgressive bone destructionFirst-line treatmentPercutaneous treatment optionsAmbulatory surgery settingProgressive bone lossSurgical reconstructive proceduresEarly clinical resultsImage-guided ablationNew effective therapiesOpen surgical proceduresInvasive surgical interventionOptimal internal fixationOsteolytic metastatic diseasePolymethyl methacrylate cementUncontrolled painMetastatic diseaseBone destructionOsteolytic metastases
2020
Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones
Lee FY, Latich I, Toombs C, Mungur A, Conway D, Alder K, Ibe I, Lindskog D, Friedlaender G. Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones. Journal Of Vascular And Interventional Radiology 2020, 31: 649-658.e1. PMID: 32139256, DOI: 10.1016/j.jvir.2019.11.029.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAdultAgedAged, 80 and overBone CementsBone NeoplasmsBone RemodelingBone ScrewsCalcaneusCementoplastyFemaleFemoral NeoplasmsFemurFracture Fixation, InternalHumansMaleMiddle AgedOsteolysisPelvic BonesPostoperative ComplicationsProspective StudiesRecovery of FunctionTibiaTime FactorsTreatment OutcomeWeight-BearingConceptsOsteolytic lesionsInternal fixationVisual analog scale pain scoreMusculoskeletal Tumor Society scoreProspective clinical cohort studyFunctional ambulation scoreOsteolytic skeletal lesionsPainful osteolytic lesionsScale pain scoresClinical cohort studyInvasive percutaneous approachWeight-bearing boneInternal fixation screwsBalloon osteoplastyPain scoresCohort studyProphylactic stabilizationSevere painSociety ScoreConsecutive patientsSurgical treatmentEarly outcomesTreatment optionsPercutaneous approachFunctional improvement
2019
Bone Quality and Fracture-Healing in Type-1 and Type-2 Diabetes Mellitus.
Henderson S, Ibe I, Cahill S, Chung YH, Lee FY. Bone Quality and Fracture-Healing in Type-1 and Type-2 Diabetes Mellitus. Journal Of Bone And Joint Surgery 2019, 101: 1399-1410. PMID: 31393433, DOI: 10.2106/jbjs.18.01297.Peer-Reviewed Original ResearchConceptsType 2 diabetesPerioperative complicationsDiabetic patientsGlycemic controlBone healthType 1Type 2 diabetes mellitusNormal bone mineral densityPerioperative glycemic controlNon-diabetic patientsEarly bone lossSurgical site infectionAppropriate glycemic controlUnion of fractureRisk of fractureBone mineral densityType 1 diabetesAntiresorptive therapyOperative interventionDiabetes mellitusSclerostin antibodySite infectionMedical managementParathyroid hormonePostoperative managementFemoral and Tibial Reconstruction for Skeletal Metastases and Pathologic Fractures.
Henderson SE, Yu K, Alder KD, Ibe IK, Lee FY, Lindskog DM. Femoral and Tibial Reconstruction for Skeletal Metastases and Pathologic Fractures. Instructional Course Lectures 2019, 68: 607-612. PMID: 32032089.Peer-Reviewed Original ResearchConceptsPathologic fractureSkeletal metastasesTibial reconstructionCommon reconstructive optionsRisk of complicationsSoft tissue involvementHistory of radiationImproved patient outcomesSubsequent revision proceduresLarge skeletal defectsGoal of reconstructionSystemic therapyGoal of managementPatient outcomesSurgical reconstructionReconstructive optionsRevision proceduresEndoprosthesis implantationIntramedullary nailImplant failureLarge bone defectsMetastasisBone defectsSkeletal defectsFractures
2007
Coronal and Sagittal Plane Correction in Adolescent Idiopathic Scoliosis
Lowenstein JE, Matsumoto H, Vitale MG, Weidenbaum M, Gomez JA, Lee FY, Hyman JE, Roye DP. Coronal and Sagittal Plane Correction in Adolescent Idiopathic Scoliosis. Spine 2007, 32: 448-452. PMID: 17304136, DOI: 10.1097/01.brs.0000255030.78293.fd.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisMain thoracic curveScrew groupSagittal balanceScrew constructsThoracic curveIdiopathic scoliosisRetrospective cohort studyPosterior spinal fusionCoronal plane deformitySagittal plane correctionBetter correctionMean thoracic kyphosisRecent clinical researchSignificant differencesPedicle screw constructsCohort studyPostoperative radiographsConstruct groupMajor curvePlane deformitySpinal fusionThoracic kyphosisHybrid groupHook constructs
2006
Treatment of Congenital Pseudarthrosis of the Tibia with Recombinant Human Bone Morphogenetic Protein-7 (rhBMP-7)
Lee F, Sinicropi S, Lee F, Vitale M, Roye D, Choi I. Treatment of Congenital Pseudarthrosis of the Tibia with Recombinant Human Bone Morphogenetic Protein-7 (rhBMP-7). Journal Of Bone And Joint Surgery 2006, 88: 627-633. PMID: 16510831, DOI: 10.2106/jbjs.d.02201.Peer-Reviewed Original ResearchTREATMENT OF CONGENITAL PSEUDARTHROSIS OF THE TIBIA WITH RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-7 (RHBMP-7)
LEE FY, SINICROPI SM, LEE FS, VITALE MG, ROYE DP, CHOI IH. TREATMENT OF CONGENITAL PSEUDARTHROSIS OF THE TIBIA WITH RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-7 (RHBMP-7). Journal Of Bone And Joint Surgery 2006, 88: 627-633. DOI: 10.2106/00004623-200603000-00023.Peer-Reviewed Original Research
2005
Correction of Adolescent Idiopathic Scoliosis Using Thoracic Pedicle Screw Fixation Versus Hook Constructs
Storer SK, Vitale MG, Hyman JE, Lee FY, Choe JC, Roye DP. Correction of Adolescent Idiopathic Scoliosis Using Thoracic Pedicle Screw Fixation Versus Hook Constructs. Journal Of Pediatric Orthopaedics 2005, 25: 415-419. PMID: 15958886, DOI: 10.1097/01.mph.0000165134.38120.87.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisThoracic pedicle screw fixationPedicle screw fixationHook constructsHook groupPatient groupScrew fixationIdiopathic scoliosisScrew groupMean preoperative Cobb angleScrew constructsPreoperative Cobb angleApical vertebral translationSignificant differencesQuality of lifeThoracic pedicle screwsThoracic pedicle screw constructsPedicle screw constructsOperative timeRetrospective studyPostoperative radiographsConsecutive casesCoronal balanceSurgical correctionSurgical time
2004
Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP).
Delloye C, Suratwala SJ, Cornu O, Lee FY. Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP). Acta Orthopaedica Belgica 2004, 70: 591-7. PMID: 15669462.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBone Morphogenetic ProteinsBone NeoplasmsBone TransplantationFemaleFollow-Up StudiesFractures, UnunitedHumansMaleMiddle AgedOsteosarcomaRadiographyRetrospective StudiesRisk AssessmentSampling StudiesSarcoma, EwingSensitivity and SpecificityTransplantation, HomologousTreatment OutcomeConceptsAllograft-host junctionAllograft nonunionRecombinant human bone morphogenetic proteinAllograft fractureIntercalary allograftsFracture nonunionHuman bone morphogenetic proteinAdditional radiation therapyMalignant bone tumorsRhBMP-7Allograft bone transplantationBone morphogenetic proteinAdjuvant chemotherapySterile drainageRadiological evidenceCorticocancellous allograftFemoral allograftsTibial nonunionWide resectionOsteoarticular allograftsTumor recurrenceMain complicationsNonunion siteBone tumorsRadiation therapySynovial Chondromatosis of the Foot
Lee F, Hornicek FJ, Dick HM, Mankin HJ. Synovial Chondromatosis of the Foot. Clinical Orthopaedics And Related Research® 2004, 423: 186-190. PMID: 15232447, DOI: 10.1097/01.blo.0000127133.89704.86.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnkle JointChondromatosis, SynovialDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTreatment OutcomeEffect of bracing on the quality of life of adolescents with idiopathic scoliosis
Ugwonali OF, Lomas G, Choe JC, Hyman JE, Lee FY, Vitale MG, Roye DP. Effect of bracing on the quality of life of adolescents with idiopathic scoliosis. The Spine Journal 2004, 4: 254-260. PMID: 15125845, DOI: 10.1016/j.spinee.2003.12.001.Peer-Reviewed Original ResearchConceptsPediatric Outcomes Data Collection InstrumentChild Health QuestionnaireAdolescent idiopathic scoliosisQoL of adolescentsObserved patientsOrthopaedic Surgeons Pediatric Outcomes Data Collection InstrumentIdiopathic scoliosisTreatment of AISHealth-related qualityPresbyterian Medical CenterQuality of lifeAge-adjusted normsQuestionnaire-based studyAIS patientsHealth QuestionnaireStudy populationMedical CenterPatientsParents of adolescentsIndependent sample t-testQoLChildren's QoLMultivariate analysisAmerican AcademyTreatment type
2003
In Situ Pinning of Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Operating Table
Lee FY, Chapman CB. In Situ Pinning of Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Operating Table. Journal Of Pediatric Orthopaedics 2003, 23: 27. PMID: 12499938, DOI: 10.1097/01241398-200301000-00005.Peer-Reviewed Original ResearchConceptsCapital femoral epiphysisFracture tableFemoral epiphysisSitu pinningFrog-leg lateral radiographsStable Slipped Capital Femoral EpiphysisTime of diagnosisSlipped Capital Femoral EpiphysisPin entry pointRadiolucent operating tableObese patientsPercutaneous pinningAvascular necrosisLateral radiographsStable SCFEPatientsRadiolucent tableOperating tableHipSCFEEpiphysis
2001
Coronal Split Fracture of the Proximal Tibia Epiphysis Through a Partially Closed Physis: A New Fracture Pattern
Patari S, Lee F, Behrens F. Coronal Split Fracture of the Proximal Tibia Epiphysis Through a Partially Closed Physis: A New Fracture Pattern. Journal Of Pediatric Orthopaedics 2001, 21: 451. PMID: 11433155, DOI: 10.1097/01241398-200107000-00007.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAdolescentBicyclingBiomechanical PhenomenaEpiphysesExternal FixatorsFollow-Up StudiesFracture Fixation, InternalFracture HealingFractures, ComminutedGaitHumansMaleRange of Motion, ArticularRisk FactorsTibial FracturesTomography, X-Ray ComputedTreatment OutcomeWeight-BearingConceptsCoronal split fractureProximal tibial epiphysisTibial epiphysisSplit fractureDefinitive operative fixationProximal tibia epiphysisNew fracture patternClinical unionUncommon injuryOperative fixationEpiphyseal fracturesPlain radiographyTibial plateauTibia epiphysisEpiphysisFracture patternsFracturesPatientsThree-dimensional reconstructionInjuryPhysis
1999
Chondrosarcoma of bone: an assessment of outcome.
Lee FY, Mankin HJ, Fondren G, Gebhardt MC, Springfield DS, Rosenberg AE, Jennings LC. Chondrosarcoma of bone: an assessment of outcome. Journal Of Bone And Joint Surgery 1999, 81: 326-38. PMID: 10199270, DOI: 10.2106/00004623-199903000-00004.Peer-Reviewed Original ResearchConceptsGrade 3 lesionsIntralesional resectionLocal recurrenceHistological gradePostoperative adjuvant radiationLimb-sparing proceduresPredictor of metastasisGroup of patientsHigh-grade lesionsLow-grade tumorsPredictors of outcomeHigh-grade tumorsAssessment of outcomesAdjuvant radiationPathological fracturesRecurrent diseasePulmonary metastasesDistant metastasisAdjunctive chemotherapyMarginal resectionMean ageMean durationPelvic locationPrevalent siteGrade 3
1998
Reconstruction Of The Shoulder Joint Using An Acetabular Allograft
Lee FY, Hornicek FJ, Hazan EJ, Kloen P, Wolfe MA, Mankin HJ. Reconstruction Of The Shoulder Joint Using An Acetabular Allograft. Clinical Orthopaedics And Related Research® 1998, 357: 120-121. PMID: 9917707, DOI: 10.1097/00003086-199812000-00015.Peer-Reviewed Original ResearchConceptsShoulder jointAcetabular allograftWide resectionMusculoskeletal Tumor Society systemStable shoulder jointAggressive lesionsOsteoarticular allograftsAggressive tumorsCosmetic resultsFunctional resultsSurgical reconstructionAllograftsSecure reattachmentPatientsSoft tissueResectionCenter of motionSelect groupScapulaTumorsGlenoid regionJointsLesions