2018
A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis
Mak W, Xia J, Cheng EC, Lowther K, Lin H. A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis. Cell & Bioscience 2018, 8: 54. PMID: 30364263, PMCID: PMC6194604, DOI: 10.1186/s13578-018-0251-1.Peer-Reviewed Original ResearchAbnormal preimplantation developmentPreimplantation developmentPumilio 1Genome-wide transcriptome analysisMaternal effect genesPost-transcriptional regulatorsMammalian oocyte maturationMaternal phaseCDK1 mRNAEmbryo transitionMammalian embryogenesisEffect genesTranscriptome analysisMaternal mRNAsMammalian systemsMRNA targetsPUM1CDK1 proteinConcomitant perturbationMeiotic maturationEmbryogenesisOocyte maturationMeiosisImportant functionsProtein
2002
The stem-cell niche theory: lessons from flies
Lin H. The stem-cell niche theory: lessons from flies. Nature Reviews Genetics 2002, 3: 931-940. PMID: 12459723, DOI: 10.1038/nrg952.Peer-Reviewed Original ResearchConceptsStem cell nicheSomatic stem cellsStem cellsTesticular stem cell nicheGermline stem cellsTerminal filament cellsSelf-renewing divisionsOogenic functionEpidermal growth factor receptorUnpaired ligandAdherens junctionsMammalian systemsTesticular nicheOvarian nicheGrowth factor receptorHub cellsPathway functionNiche theoryFilament cellsGermlineCell adhesionNicheFactor receptorPathwayFlies