2024
Self-Assembled Fibroblast Growth Factor Nanoparticles as a Therapeutic for Oxidant-Induced Neuronal and Skin Cell Injury
Kumar S, Chu A, Theis T, Rastogi S, Costea D, Banerjee R, Das B, Yarmush M, Hsia H, Cohen R, Schachner M, Berthiaume F. Self-Assembled Fibroblast Growth Factor Nanoparticles as a Therapeutic for Oxidant-Induced Neuronal and Skin Cell Injury. ACS Applied Bio Materials 2024, 7: 5158-5170. PMID: 39038169, DOI: 10.1021/acsabm.4c00135.Peer-Reviewed Original ResearchSpinal cord injuryFGF-2Cell injuryTraumatic brain injurySkin wound healingResponses in vivoInflammatory response in vivoWound healingPressure woundsOxidant-mediated injuryFibroblast growth factor-2Growth factor 2Delayed injuryLocal inflammationNanoparticle sizeChronic skin woundsSecondary complicationsCultured neuronal cellsEndothelial cellsGrowth factorPromote neurite outgrowthCord injuryNeurological sensationsRecombinant fusion proteinNanoparticles
2015
SDF‐1 liposomes promote sustained cell proliferation in mouse diabetic wounds
Olekson MA, Faulknor R, Bandekar A, Sempkowski M, Hsia HC, Berthiaume F. SDF‐1 liposomes promote sustained cell proliferation in mouse diabetic wounds. Wound Repair And Regeneration 2015, 23: 711-723. PMID: 26110250, DOI: 10.1111/wrr.12334.Peer-Reviewed Original ResearchConceptsStromal cell-derived factor-1Acellular dermisCell-derived factor-1Cell proliferationRestoration of skinChronic skin woundsImproved wound closurePersistent cell proliferationCommon complicationGranulation tissue thicknessIschemic tissueProper revascularizationDay 28Day 21Diabetic woundsSuch woundsWound closureSkin woundsDermisFactor 1Tissue thicknessWoundsProliferation