2023
The effects of age on the severity of problem drinking: Mediating effects of positive alcohol expectancy and neural correlates
Chaudhary S, Chen Y, Zhornitsky S, Le T, Zhang S, Chao H, Dominguez J, Li C. The effects of age on the severity of problem drinking: Mediating effects of positive alcohol expectancy and neural correlates. Addiction Biology 2023, 28: e13278. PMID: 37252876, DOI: 10.1111/adb.13278.Peer-Reviewed Original ResearchConceptsPositive alcohol expectanciesAlcohol Use Disorders Identification TestAlcohol expectanciesAlcohol use disorderNeural correlatesCue responsesPath analysisProblem drinkingAlcohol misuseEffect of ageAUDIT scoresRostral anterior cingulate cortexWhole-brain regressionAlcohol cue exposureMiddle occipital cortexModerate alcohol use disorderAlcohol Expectancy QuestionnaireAnterior cingulate cortexAlcohol use severityBilateral rostral anterior cingulate cortexPsychological mechanismsBilateral parahippocampal gyrusCue exposureNeural processesSeverity of problems
2009
Activation of the pre-supplementary motor area but not inferior prefrontal cortex in association with short stop signal reaction time – an intra-subject analysis
Chao H, Luo X, Chang J, Li CS. Activation of the pre-supplementary motor area but not inferior prefrontal cortex in association with short stop signal reaction time – an intra-subject analysis. BMC Neuroscience 2009, 10: 75. PMID: 19602259, PMCID: PMC2719646, DOI: 10.1186/1471-2202-10-75.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeRight inferior prefrontal cortexStop-signal taskPre-supplementary motor areaShorter stop-signal reaction timesInferior prefrontal cortexSignal reaction timePrefrontal cortexResponse inhibitionMotor areaMiddle/posterior cingulate cortexMotor response inhibitionInferior frontal cortexRegional brain activationStop-signal inhibitionLonger stop-signal reaction timesInhibitory motor controlPosterior cingulate cortexMedial prefrontal cortexReaction timeGreater activityAttentional monitoringNeural processesSignal taskBrain activation
2008
Neural Correlates of Speeded as Compared with Delayed Responses in a Stop Signal Task: An Indirect Analog of Risk Taking and Association with an Anxiety Trait
Li CS, Chao H, Lee TW. Neural Correlates of Speeded as Compared with Delayed Responses in a Stop Signal Task: An Indirect Analog of Risk Taking and Association with an Anxiety Trait. Cerebral Cortex 2008, 19: 839-848. PMID: 18678764, PMCID: PMC2722793, DOI: 10.1093/cercor/bhn132.Peer-Reviewed Original ResearchConceptsStop-signal taskSignal taskReaction timeTrial reaction timeStop-signal performanceFunctional magnetic resonanceMiddle frontal gyrusAdvantage of variabilityBilateral visual cortexPosterior cingulate cortexCognitive controlNeural correlatesNeural processesAmygdala activityTrait anxietyFrontal gyrusAnxiety traitsBehavioral paradigmsIndirect analogueCingulate cortexNeural analogRisk takingVisual cortexStop signalCurrent study