2021
Clinical Management of Anemia in Patients with Myelodysplastic Syndromes: An Update on Emerging Therapeutic Options
Lewis R, Bewersdorf JP, Zeidan AM. Clinical Management of Anemia in Patients with Myelodysplastic Syndromes: An Update on Emerging Therapeutic Options. Cancer Management And Research 2021, 13: 645-657. PMID: 33531837, PMCID: PMC7846829, DOI: 10.2147/cmar.s240600.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLower-risk myelodysplastic syndromesErythropoiesis-stimulating agentsTherapeutic optionsSymptomatic anemiaMyelodysplastic syndromeRed blood cell transfusionFurther therapeutic optionsBlood cell transfusionAvailable therapeutic optionsMajority of patientsManagement of anemiaPrimary clinical goalQuality of lifeResultant cytopeniasCell transfusionFrequent transfusionsImmunosuppressive therapyClinical improvementMost patientsSelect patientsTransfusion burdenClinical managementIron overloadNovel agentsAdditional therapeutics
2019
Use of immunosuppressive therapy for management of myelodysplastic syndromes: a systematic review and meta-analysis
Stahl M, Bewersdorf J, Giri S, Wang R, Zeidan AM. Use of immunosuppressive therapy for management of myelodysplastic syndromes: a systematic review and meta-analysis. Haematologica 2019, 105: 102-111. PMID: 31004015, PMCID: PMC6939518, DOI: 10.3324/haematol.2019.219345.Peer-Reviewed Original ResearchConceptsImmunosuppressive therapyProspective cohort studyMyelodysplastic syndromeClinical trialsResponse rateCohort studySystematic reviewLower-risk myelodysplastic syndromesLow-risk MDS patientsDifferent immunosuppressive regimensTransfusion independence rateAnti-thymocyte globulinComplete remission rateRelevant conference proceedingsOverall response rateTreatment of patientsAcute myeloid leukemiaHigh-quality studiesHigh response rateRandom-effects modelWeb of ScienceImmunosuppressive regimensPatient yearsRemission rateAdverse events