2023
A generalizable new figure of merit for dose optimization in dual energy cone beam CT scanning protocols
Li C, Zhou L, Deng J, Wu H, Wang R, Wang F, Yao K, Chen C, Niu T, Zhang Y. A generalizable new figure of merit for dose optimization in dual energy cone beam CT scanning protocols. Physics In Medicine And Biology 2023, 68: 185021. PMID: 37619587, DOI: 10.1088/1361-6560/acf3cd.Peer-Reviewed Original Research
2020
A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation
Liang Y, Muhammad W, Hart GR, Nartowt BJ, Chen ZJ, Yu JB, Roberts KB, Duncan JS, Deng J. A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation. Scientific Reports 2020, 10: 9808. PMID: 32555530, PMCID: PMC7300009, DOI: 10.1038/s41598-020-66844-7.Peer-Reviewed Original ResearchConceptsPhoton transportBoundary crossing algorithmMonte Carlo particle transport codeMonte Carlo methodTransport simulationsAcceptance-rejection samplingRadiotherapy dose calculationsPhoto-electric effectParticle transport codeEGSnrc simulationsCarlo methodBremsstrahlung eventsInelastic scatteringPair productionRayleigh scatteringThread divergenceMC simulationsTransport codeMC codeHistory schemeParticle transportCrossing algorithmInverseElectron transportSimulation accuracy
2018
Imaging Dose, Cancer Risk and Cost Analysis in Image-guided Radiotherapy of Cancers
Zhou L, Bai S, Zhang Y, Ming X, Zhang Y, Deng J. Imaging Dose, Cancer Risk and Cost Analysis in Image-guided Radiotherapy of Cancers. Scientific Reports 2018, 8: 10076. PMID: 29973695, PMCID: PMC6031630, DOI: 10.1038/s41598-018-28431-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBone Marrow CellsBrainChildChild, PreschoolCone-Beam Computed TomographyCost-Benefit AnalysisFemaleHumansInfantLungMaleMiddle AgedMonte Carlo MethodNeoplasmsPhantoms, ImagingRadiation DosageRadiotherapy DosageRadiotherapy, Image-GuidedRisk FactorsThoraxYoung AdultConceptsCancer riskAssociated cancer riskImage-guided radiotherapyImaging proceduresLifetime attributable riskImaging dosesAverage lifetime attributable riskRadiological imaging proceduresRed bone marrowRetrospective studyCancer patientsLung cancerAttributable riskCancer incidenceBilling codesIndividual patientsBone marrowBrain cancerImage guidance proceduresPelvic scanPatientsCancerOrgan dosesRadiotherapyDoses
2017
A measurement-based generalized source model for Monte Carlo dose simulations of CT scans
Ming X, Feng Y, Liu R, Yang C, Zhou L, Zhai H, Deng J. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans. Physics In Medicine And Biology 2017, 62: 1759-1776. PMID: 28079526, PMCID: PMC5857954, DOI: 10.1088/1361-6560/aa5911.Peer-Reviewed Original ResearchConceptsMonte Carlo dose simulationsGeneralized source modelEnergy spectrumFluence distributionDose profilesCentral axis percent depth dose curvePercent depth dose curvesDose simulationsDepth dose curvesMonte Carlo user codeSource distributionBeam inputDose curvesFilm measurementsCTDI phantomCT scannerOutput factorsAbsolute dose comparisonsMonte Carlo simulationsDose distributionSource modelCarlo simulationsCircular sourceGE LightspeedScanner specifications
2015
Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy
Zhang Y, Wu H, Chen Z, Knisely JP, Nath R, Feng Z, Bao S, Deng J. Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 523-531. PMID: 26460994, DOI: 10.1016/j.ijrobp.2015.06.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAorta, ThoracicBody SizeBreastChildChild, PreschoolCone-Beam Computed TomographyFemaleHeartHumansLungMaleMiddle AgedMonte Carlo MethodOrgans at RiskPhantoms, ImagingPhotonsPrecision MedicineProtonsRadiation DosageRadiography, ThoracicRadiotherapy, Image-GuidedRisk AssessmentSex FactorsSpinal CordThoracic WallThoraxConceptsConcomitant imaging doseThoracic radiation therapyCancer riskRadiation therapyMean dosesCardiac substructuresKilovoltage cone-beamImaging doseAdverse eventsPediatric patientsMedian dosesCancer patientsRight ventricleExtra radiation doseSpinal cordHigh dosesPatientsCone beamPlanning CT imagesChest dimensionsDosesPatient sizeImaging guidanceTherapyDose
2012
Personalized Assessment of kV Cone Beam Computed Tomography Doses in Image-guided Radiotherapy of Pediatric Cancer Patients
Zhang Y, Yan Y, Nath R, Bao S, Deng J. Personalized Assessment of kV Cone Beam Computed Tomography Doses in Image-guided Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2012, 83: 1649-1654. PMID: 22285667, DOI: 10.1016/j.ijrobp.2011.10.072.Peer-Reviewed Original ResearchAdolescentAge FactorsBody SizeBody WeightChildChild, PreschoolCone-Beam Computed TomographyFemaleHeadHumansMaleMonte Carlo MethodNeoplasmsOrgans at RiskPelvisPhantoms, ImagingRadiation DosageRadiation InjuriesRadiotherapy Planning, Computer-AssistedRadiotherapy, Image-GuidedRetrospective StudiesYoung Adult
2011
Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer
Deng J, Chen Z, Yu JB, Roberts KB, Peschel RE, Nath R. Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: e39-e47. PMID: 21489702, DOI: 10.1016/j.ijrobp.2011.01.071.Peer-Reviewed Original ResearchConceptsImage-guided radiotherapyTesticular dosesFull-fan modeProstate cancerFemoral headLess doseCBCT scansHalf-fan modeProstate cancer patientsKilovoltage cone-beamCancer patientsIntensity-modulated radiotherapy (IMRT) treatmentKilovoltage CBCTSuperior-inferior directionCone beamDosesCBCT fieldProstate patientsRectumDoseProstateMore doseRadiotherapy treatmentPatientsRadiotherapyKilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients
Deng J, Chen Z, Roberts KB, Nath R. Kilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: 1680-1688. PMID: 21477943, DOI: 10.1016/j.ijrobp.2011.01.062.Peer-Reviewed Original ResearchConceptsPediatric cancer patientsCancer patientsTesticular shieldingSpinal cordKilovoltage cone-beamCBCT dosesMean dosesClinical conditionsDose reductionLarge dosesFemoral headPatientsCBCT scansCone beamDosesFull-fan modeOptical nerveCBCT fieldCordDose increaseImaging dosesScanning protocolOARsRadiotherapyHalf-fan mode
2008
Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA
Ahmad M, Deng J, Lund MW, Chen Z, Kimmett J, Moran MS, Nath R. Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA. Physics In Medicine And Biology 2008, 54: 447-465. PMID: 19098353, DOI: 10.1088/0031-9155/54/2/018.Peer-Reviewed Original Research
2004
Modelling 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning
Deng J, Guerrero T, Ma C, Nath R. Modelling 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning. Physics In Medicine And Biology 2004, 49: 1689-1704. PMID: 15152924, DOI: 10.1088/0031-9155/49/9/007.Peer-Reviewed Original ResearchMeSH KeywordsModels, TheoreticalMonte Carlo MethodParticle AcceleratorsPhantoms, ImagingPhotonsRadiosurgeryRadiotherapy DosageConceptsMV photon beamMonte Carlo treatmentPhoton beamsPhase spaceEGS4/BEAM systemPercent depth dose curvesParticle phase spaceMonte Carlo treatment planningDepth dose curvesFull phase spaceDose calculationsStereotactic radiosurgery systemContaminant electronsCircular planar sourceMonte Carlo systemPrimary photonsMultiple source modelDose profilesSecondary collimatorDose curvesTotal maximum doseDose contributionBeamBeam systemOriginal phase space
2003
Dose correlation for thoracic motion in radiation therapy of breast cancer
Ding M, Li J, Deng J, Fourkal E, Ma C. Dose correlation for thoracic motion in radiation therapy of breast cancer. Medical Physics 2003, 30: 2520-2529. PMID: 14528974, DOI: 10.1118/1.1603744.Peer-Reviewed Original ResearchMeSH KeywordsArtifactsBreast NeoplasmsHumansMammographyMotionMovementOnline SystemsPhantoms, ImagingRadiographic Image Interpretation, Computer-AssistedRadiography, ThoracicRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsRespirationSensitivity and SpecificityStatistics as TopicThoraxTomography, X-Ray ComputedConceptsBreathing patternDose correlationBreast cancerChest wall motionChest wall movementPatient's breathing patternDose dataRadiation therapyThoracic motionRadiotherapy treatmentTreatment planningExpiration phaseDifferent breathing phasesFinal dose distributionCancerBreathing phasesPatient anatomyWall motionTreatmentDose distributionCT dataBreathing levelTherapyDosePatient geometryA quality assurance phantom for IMRT dose verification
Ma C, Jiang SB, Pawlicki T, Chen Y, Li JS, Deng J, Boyer AL. A quality assurance phantom for IMRT dose verification. Physics In Medicine And Biology 2003, 48: 561-572. PMID: 12696795, DOI: 10.1088/0031-9155/48/5/301.Peer-Reviewed Original Research
2002
A Monte Carlo dose calculation tool for radiotherapy treatment planning
Ma C, Li JS, Pawlicki T, Jiang SB, Deng J, Lee MC, Koumrian T, Luxton M, Brain S. A Monte Carlo dose calculation tool for radiotherapy treatment planning. Physics In Medicine And Biology 2002, 47: 1671-1689. PMID: 12069086, DOI: 10.1088/0031-9155/47/10/305.Peer-Reviewed Original Research
2001
Monte Carlo based treatment planning for modulated electron beam radiation therapy
Lee M, Deng J, Li J, Jiang S, Ma C. Monte Carlo based treatment planning for modulated electron beam radiation therapy. Physics In Medicine And Biology 2001, 46: 2177-2199. PMID: 11512618, DOI: 10.1088/0031-9155/46/8/310.Peer-Reviewed Original ResearchConceptsElectron multileaf collimatorIntensity mapsDose distributionElectron radiation therapyElectron beamletsElectron energyElectron beam radiation therapyAir scatteringMonte CarloBremsstrahlung contributionConformal dose distributionsMonte Carlo simulationsBeamletsScatter dosesTreatment planning systemElectronsMultileaf collimatorCarlo simulationsBreast plansIrregular targetsLeaf transportCarloScatteringMonte Carlo generationCollimator
2000
Validation of a Monte Carlo dose calculation tool for radiotherapy treatment planning
Li JS, Pawlicki T, Deng J, Jiang SB, Mok E, Ma C. Validation of a Monte Carlo dose calculation tool for radiotherapy treatment planning. Physics In Medicine And Biology 2000, 45: 2969-2985. PMID: 11049183, DOI: 10.1088/0031-9155/45/10/316.Peer-Reviewed Original ResearchMonte Carlo verification of IMRT dose distributions from a commercial treatment planning optimization system
Ma C, Pawlicki T, Jiang SB, Li JS, Deng J, Mok E, Kapur A, Xing L, Ma L, Boyer AL. Monte Carlo verification of IMRT dose distributions from a commercial treatment planning optimization system. Physics In Medicine And Biology 2000, 45: 2483-2495. PMID: 11008950, DOI: 10.1088/0031-9155/45/9/303.Peer-Reviewed Original ResearchConceptsMonte Carlo simulationsFinite-size pencil beam (FSPB) algorithmCorvus systemCarlo simulationsOptimization systemIMRT dose distributionsRadiotherapy dose calculationsMonte Carlo treatment planning systemPencil beam algorithmDose distributionMonte CarloBeam algorithmHeterogeneous phantomsMonte Carlo verificationHomogeneous phantomBeam energyCylindrical water phantomIMRT fieldsDose calculationsWater phantomTreatment planning systemField sizeTarget shapeAlgorithmSimulationsEnergy- and intensity-modulated electron beams for radiotherapy
Ma C, Pawlicki T, Lee MC, Jiang SB, Li JS, Deng J, Yi B, Mok E, Boyer AL. Energy- and intensity-modulated electron beams for radiotherapy. Physics In Medicine And Biology 2000, 45: 2293-2311. PMID: 10958195, DOI: 10.1088/0031-9155/45/8/316.Peer-Reviewed Original ResearchConceptsModulated electron radiotherapyIntensity-modulated electron beamElectron beamMultileaf collimatorElectron beam energyInter-leaf leakageDose distributionElectron intraMonte Carlo dose calculationsPencil beam algorithmLeaf endsBeam energyPhoton beamsElectron radiotherapyOblique incidencePatient surfaceMonte Carlo methodBeamBeam algorithmField shapeMonte Carlo simulationsDose calculationsSuperficial targetsCarlo methodCarlo simulationsPhoton beam characterization and modelling for Monte Carlo treatment planning
Deng J, Jiang S, Kapur A, Li J, Pawlicki T, Ma C. Photon beam characterization and modelling for Monte Carlo treatment planning. Physics In Medicine And Biology 2000, 45: 411-427. PMID: 10701512, DOI: 10.1088/0031-9155/45/2/311.Peer-Reviewed Original ResearchMeSH KeywordsModels, TheoreticalMonte Carlo MethodParticle AcceleratorsPhantoms, ImagingPhotonsRadiotherapy Planning, Computer-AssistedSoftwareConceptsOriginal phase spacePhase spaceMonte Carlo calculationsPhoton jawsCarlo calculationsMonte Carlo treatment planningSource-surface distanceVarian Clinac 2100CPhase space filesPrimary collimatorMultiple source modelPhoton beamsPlanar fluenceAngular distributionsMV photon beamClinac 2100CField sizeSource modelBeam characterizationDose distributionHeterogeneous phantomsGood agreementBeam characteristicsFlattening filterEnergy spectrum