2019
Adaptive Immunity: Antigen Recognition by T and B Lymphocytes
Kavathas P, Krause P, Ruddle N. Adaptive Immunity: Antigen Recognition by T and B Lymphocytes. 2019, 55-74. DOI: 10.1007/978-3-030-25553-4_4.ChaptersB cell receptorCell receptorMajor histocompatibility complexB lymphocytesKiller T cellsEffective immune responseVariety of antigensT cell receptors (TCRs) bindCentral toleranceT cellsImmune responseHLA proteinsAntigen recognitionHistocompatibility complexIntracellular pathogensCell surfaceReceptorsHLALymphocytesCorresponding antibodiesHost cellsAntibodiesIsotypesMHC systemDefense mechanismsImmunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems
Ruddle N, Kavathas P. Immunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems. 2019, 111-125. DOI: 10.1007/978-3-030-25553-4_7.Peer-Reviewed Original ResearchKiller cell immunoglobulin-like receptorsPattern recognition receptorsT cell receptorMajor histocompatibility complexImmune systemSingle nucleotide polymorphismsImmunoglobulin-like receptorsAdaptive immune systemImmune responseRecognition receptorsPresence of polymorphismsCell receptorHistocompatibility complexGenetic polymorphismsReceptorsSelective survivalPolymorphismApparent effectMultiple microorganismsPregnancyChemokinesCytokinesImmunoepidemiologyInfectionInnate
2016
Lymphotoxin
Ruddle N. Lymphotoxin. 2016, 466-475. DOI: 10.1016/b978-0-12-374279-7.10003-7.Peer-Reviewed Original ResearchTumor necrosis factorNFκB pathwayChronic inflammatory infiltrateAlternative NFκB pathwayMajor histocompatibility complexLymph nodesInflammatory infiltrateChemokine expressionChronic inflammationLymphoid organsNecrosis factorImmune responseCanonical NFκB pathwaySpecific antigenTNF receptorLymphotoxinLTβ receptorHistocompatibility complexTNF familyCulture supernatantsEmbryological developmentLymphocytesLTαCytotoxic activityReceptors