2024
Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer
Siddique S, Baum L, Deziel N, Kelly J, Warren J, Ma X. Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer. PLOS ONE 2024, 19: e0311540. PMID: 39471191, PMCID: PMC11521299, DOI: 10.1371/journal.pone.0311540.Peer-Reviewed Original ResearchConceptsAge-of-onset colorectal cancerEarly-onset colorectal cancerEnd Results Program dataCenters for Disease Control and Prevention dataCounty-level factorsColorectal cancerHealth risk behaviorsIdentified principal componentsOdds of survivalPreventive servicesSurvival disparitiesLinear mixed modelsEOCRCChronic diseasesPreventive factorsUS countiesSalt Lake CountyCA residentsRisk behaviorsUnited StatesProgram dataCounty-levelOlder ageBayesian analytical approachYounger age
2020
Exposure to polychlorinated biphenyls and organochlorine pesticides and thyroid cancer in connecticut women
Deziel NC, Warren JL, Huang H, Zhou H, Sjodin A, Zhang Y. Exposure to polychlorinated biphenyls and organochlorine pesticides and thyroid cancer in connecticut women. Environmental Research 2020, 192: 110333. PMID: 33068584, PMCID: PMC7736223, DOI: 10.1016/j.envres.2020.110333.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerThyroid cancerPCBs/OCPsOdds ratioSubsequent thyroid cancer riskMulti-pollutant modelingSerum Polychlorinated BiphenylsBody mass indexConfidence intervalsThyroid cancer riskThyroid cancer incidenceEarly life exposureEnvironmental risk factorsSingle-pollutant modelsLogistic regression modelsIsotope dilution high-resolution mass spectrometryMass indexTumor sizeCancer incidenceRisk factorsConnecticut womenFamily historyMulti-pollutant analysisCancer riskThyroid hormone disruptors
2019
Exposure to Polybrominated Diphenyl Ethers and a Polybrominated Biphenyl and Risk of Thyroid Cancer in Women: Single and Multi-Pollutant Approaches
Deziel NC, Alfonso-Garrido J, Warren JL, Huang H, Sjodin A, Zhang Y. Exposure to Polybrominated Diphenyl Ethers and a Polybrominated Biphenyl and Risk of Thyroid Cancer in Women: Single and Multi-Pollutant Approaches. Cancer Epidemiology Biomarkers & Prevention 2019, 28: 1755-1764. PMID: 31387967, PMCID: PMC6774868, DOI: 10.1158/1055-9965.epi-19-0526.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerThyroid cancerPTC riskLipid-adjusted serum concentrationsPapillary thyroid cancer casesMulti-pollutant approachSerum samplesMulti-pollutant modelingThyroid cancer incidenceInterquartile range increaseThyroid cancer casesMulti-pollutant modelsSingle-pollutant modelsLogistic regression modelsPBB exposureDecreased riskProspective studySerum concentrationsCancer incidenceCancer casesAlcohol consumptionFemale controlsLow categoryConfidence intervalsPBB mixture
2018
Cell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut
Luo J, Deziel NC, Huang H, Chen Y, Ni X, Ma S, Udelsman R, Zhang Y. Cell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut. Annals Of Epidemiology 2018, 29: 39-45. PMID: 30446214, PMCID: PMC6344271, DOI: 10.1016/j.annepidem.2018.10.004.Peer-Reviewed Original ResearchConceptsPopulation-based case-control studyCase-control studyThyroid cancerThyroid microcarcinomaOdds ratioUnconditional logistic regressionPopulation-based controlsThyroid cancer casesWarrants further investigationCancer casesSuggestive increaseElevated riskCell phone useSignificant associationCancerLogistic regressionMicrocarcinomaMore frequent usersConfidence intervalsRiskFrequent usersPhone useFurther investigationAssociationHoursA case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women
Deziel NC, Yi H, Stapleton HM, Huang H, Zhao N, Zhang Y. A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women. BMC Cancer 2018, 18: 637. PMID: 29871608, PMCID: PMC5989427, DOI: 10.1186/s12885-018-4553-9.Peer-Reviewed Original ResearchConceptsCase-control studyThyroid cancer riskPFR exposureThyroid cancerPFR metabolitesOdds ratioCancer riskPapillary thyroid cancer casesUrinary biomarker measurementsTime of diagnosisLarger tumor sizeCancer case-control studySpot urine samplesThyroid cancer casesPapillary thyroid cancer riskTumor sizePotential confoundersThyroid hormone regulationUrinary concentrationsCancer casesMultiple linear regression analysisFemale controlsLinear regression analysisBackgroundGrowing evidenceBiomarker measurements
2017
Occupational exposure to pesticides and other biocides and risk of thyroid cancer
Zeng F, Lerro C, Lavoué J, Huang H, Siemiatycki J, Zhao N, Ma S, Deziel NC, Friesen MC, Udelsman R, Zhang Y. Occupational exposure to pesticides and other biocides and risk of thyroid cancer. Occupational And Environmental Medicine 2017, 74: 502. PMID: 28202579, PMCID: PMC5572578, DOI: 10.1136/oemed-2016-103931.Peer-Reviewed Original ResearchConceptsThyroid cancerOccupational exposurePopulation-based case-control studyIncident thyroid cancer casesUnconditional logistic regression modelsCase-control studyPapillary thyroid cancerThyroid cancer casesJob-exposure matrixLogistic regression modelsHigher cumulative probabilityPotential confoundersThyroid microcarcinomaCancer casesHigh riskSignificant associationCancerObserved associationsCumulative probabilityStrong associationRiskAssociationExposureFurther investigationRegression models
2013
Environmental Determinants of Polychlorinated Biphenyl Concentrations in Residential Carpet Dust
DellaValle CT, Wheeler DC, Deziel NC, De Roos AJ, Cerhan JR, Cozen W, Severson RK, Flory AR, Locke SJ, Colt JS, Hartge P, Ward MH. Environmental Determinants of Polychlorinated Biphenyl Concentrations in Residential Carpet Dust. Environmental Science And Technology 2013, 47: 10405-10414. PMID: 23952055, PMCID: PMC4076890, DOI: 10.1021/es401447w.Peer-Reviewed Original Research
2012
A multi-day environmental study of polycyclic aromatic hydrocarbon exposure in a high-risk region for esophageal cancer in China
Deziel NC, Wei WQ, Abnet CC, Qiao YL, Sunderland D, Ren JS, Schantz MM, Zhang Y, Strickland PT, Abubaker S, Dawsey SM, Friesen MC, Roth MJ. A multi-day environmental study of polycyclic aromatic hydrocarbon exposure in a high-risk region for esophageal cancer in China. Journal Of Exposure Science & Environmental Epidemiology 2012, 23: 52-59. PMID: 22805987, PMCID: PMC3504638, DOI: 10.1038/jes.2012.73.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAir PollutantsChinaEnvironmental ExposureEsophageal NeoplasmsHumansMiddle AgedPolycyclic CompoundsConceptsEsophageal cancerEsophageal squamous cell carcinomaSquamous cell carcinomaMixed effects modelsDaily urine samplesDuplicate diet samplesPolycyclic aromatic hydrocarbon exposureAromatic hydrocarbon exposureCell carcinomaUnique polycyclic aromatic hydrocarbonUrinary PAH biomarkersPAH biomarkersConsecutive daysFurther evaluationHigh-risk regionsPmol/Urine samplesPAH exposureHydrocarbon exposureHigh rateCancerElevated ratesExposureDaysDiet samples
2011
Comparison of Standard Methods for Assessing Dietary Intake of Benzo[a]pyrene
Deziel NC, Strickland PT, Platz EA, Abubaker S, Buckley TJ. Comparison of Standard Methods for Assessing Dietary Intake of Benzo[a]pyrene. Cancer Epidemiology Biomarkers & Prevention 2011, 20: 962-970. PMID: 21430297, PMCID: PMC4618457, DOI: 10.1158/1055-9965.epi-10-1344.Peer-Reviewed Original ResearchConceptsFood frequency questionnaireBaP intakeExposure assessment methodsDiet diariesMeat intakeResidue databaseFrequency questionnaireStrength of associationDietary intakeNondietary exposureConsiderable unexplained variabilityBiomarker measurementsIntakeLimited correlationSpearman correlationCancerInconsistent presenceBaselineExposureInterpersonal variabilityStandard methodsDiaryNonsmokersUnexplained variabilityAssessment methods