2022
Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET)
Rossano S, Toyonaga T, Berg E, Lorence I, Fowles K, Nabulsi N, Ropchan J, Li S, Ye Y, Felchner Z, Kukis D, Huang Y, Benveniste H, Tarantal AF, Groman S, Carson RE. Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET). European Journal Of Nuclear Medicine And Molecular Imaging 2022, 49: 3679-3691. PMID: 35633376, PMCID: PMC9826644, DOI: 10.1007/s00259-022-05825-6.Peer-Reviewed Original ResearchConceptsPositron emission tomographySynaptic densityFetal brainThird trimesterEmission tomographyBrain developmentGravid rhesus monkeysPost-mortem brain tissueEarly neonatal periodNonhuman primate brainLate gestational periodSubset of subjectsPostnatal brain developmentPost-mortem samplesGestational ageNeonatal periodPregnant monkeysSynapse numberGestational periodPrimary motorPrimate brainBrain growthSubcortical regionsBrain tissueCortical regions
1998
Muscarinic Cholinergic Receptor Measurements With [18F]FP-TZTP: Control and Competition Studies
Carson R, Kiesewetter D, Jagoda E, Der M, Herscovitch P, Eckelman W. Muscarinic Cholinergic Receptor Measurements With [18F]FP-TZTP: Control and Competition Studies. Cerebrovascular And Brain Metabolism Reviews 1998, 18: 1130-1142. PMID: 9778190, DOI: 10.1097/00004647-199810000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAnesthesiaAnesthetics, InhalationAnimalsBinding, CompetitiveBlood ProteinsBrainCholinesterase InhibitorsChromatography, Thin LayerFluorine RadioisotopesIsofluraneKineticsMacaca mulattaModels, NeurologicalPhysostigminePyridinesReceptors, MuscarinicThiazolesTomography, Emission-ComputedConceptsCholinergic receptorsBasal gangliaMuscarinic cholinergic receptorsPositron emission tomography studyM2 cholinergic receptorsMuscarinic cholinergic ligandEmission tomography studiesPositron emission tomographyBrain acetylcholineIntravenous infusionMuscarinic receptorsHigh AChE activityControl studyML xSubcortical regionsAlzheimer's diseaseGray matterCortical regionsEmission tomographyRhesus monkeysArterial input functionTomography studyCholinergic ligandsTracer injectionAChE activity