Quantifying selection in high-throughput Immunoglobulin sequencing data sets
Yaari G, Uduman M, Kleinstein SH. Quantifying selection in high-throughput Immunoglobulin sequencing data sets. Nucleic Acids Research 2012, 40: e134-e134. PMID: 22641856, PMCID: PMC3458526, DOI: 10.1093/nar/gks457.Peer-Reviewed Original ResearchConceptsQuantifying selectionDifferent selection pressuresHigh-throughput immunoglobulinSomatic hypermutationNext-generation sequencing dataDNA mutation patternsSomatic mutation patternsGroups of sequencesAntigen-driven selection processMutation patternsSequence dataSelection pressureSequencing dataB cell affinity maturationB-cell cancersNegative selectionQuantifying selection in high-throughput Immunoglobulin sequencing datasets (58.4)
Yaari G, Uduman M, Kleinstein S. Quantifying selection in high-throughput Immunoglobulin sequencing datasets (58.4). The Journal Of Immunology 2012, 188: 58.4-58.4. DOI: 10.4049/jimmunol.188.supp.58.4.Peer-Reviewed Original Research