2019
Semiautomated Measure of Abdominal Adiposity Using Computed Tomography Scan Analysis
Srikumar T, Siegel E, Gu Y, Balagurunathan Y, Garcia A, Chen Y, Zhou J, Zhao X, Gillies R, Clark W, Gamenthaler A, Choi J, Shibata D. Semiautomated Measure of Abdominal Adiposity Using Computed Tomography Scan Analysis. Journal Of Surgical Research 2019, 237: 12-21. PMID: 30694786, PMCID: PMC7771581, DOI: 10.1016/j.jss.2018.11.027.Peer-Reviewed Original ResearchConceptsVisceral fat areaSubcutaneous fat areaTotal fat areaFat areaTomography scan analysisAbdominal adiposityIntraclass correlationL4-L5 intervertebral levelAverage body mass indexSubcutaneous fat ratioBody mass indexMedian ageRectal adenocarcinomaRisk stratificationMass indexIntervertebral levelObesity epidemicRadiologic methodsAdipose tissueSemiautomated measureAdiposityFat ratioHuman pathophysiologyImaging suiteSemiautomated method
2016
Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers
Kothari N, Teer J, Abbott A, Srikumar T, Zhang Y, Yoder S, Brohl A, Kim R, Reed D, Shibata D. Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers. Cancer 2016, 122: 2828-2835. PMID: 27244218, PMCID: PMC5014625, DOI: 10.1002/cncr.30082.Peer-Reviewed Original ResearchConceptsColorectal cancerYounger patientsExome sequencingOutcomes of patientsSporadic colorectal cancerUnique genetic alterationsFisher's exact testCRC data setsWhole-exome sequencingWorse survivalRetrospective studyTreatment modalitiesBRAF mutationsPatientsExact testFBXW7 geneLarger studyOlder agePatient samplesCohortFinal analysisSporadic cancersStatistical significanceGenetic alterationsFuture screening