About
Titles
Professor of Nursing
Biography
Dr. Knobf holds a master's degree from the Yale School of Nursing and a nursing doctorate from University of Pennsylvania. Dr. Knobf's clinical practice with women with breast cancer over the past three decades has been foundational to her clinical scholarship and program of research. Her initial research study on the phenomena of weight gain in women with breast cancer on adjuvant therapy, published in 1983, resulted from the observed distress of the women experiencing a change in weight. The concept of symptom distress became an integral component in her research.
Leadership in Oncology Nursing began early in her career, being elected to the Board of Directors of the Oncology Nursing Society in 1977. Dr. Knobf's contributions to nursing have been recognized through multiple awards including the Oncology Nursing Society Excellence in Breast Cancer Education award, the Yale School of Nursing Annie Goodrich Teaching award, American Cancer Society Bronze Medal, Distinguished Service award and was the American Cancer Society Professor of Oncology Nursing. Dr. Knobf's expertise has interdisciplinary recognition and she has been selected to participate in national forums related to breast cancer.
Appointments
Departments & Organizations
- Cancer Prevention and Control
- Nursing Website
- Obesity Research Working Group
- Yale Cancer Center
Research
Overview
Medical Subject Headings (MeSH)
Chemotherapy, Adjuvant
Research at a Glance
Yale Co-Authors
Frequent collaborators of Tish Knobf's published research.
Publications Timeline
A big-picture view of Tish Knobf's research output by year.
Research Interests
Research topics Tish Knobf is interested in exploring.
Arietta Slade, PhD
Karl Insogna, MD, FACP
LaRon Nelson, PhD, RN, FAAN
Lois S. Sadler, FAAN, RN, PhD
Margaret Holland, PhD, MPH
Meena S. Moran, MD
35Publications
992Citations
Chemotherapy, Adjuvant
Publications
2024
Integrating the symptom experience and coping in patients with stage I-III breast cancer in China: A qualitative study
Liang M, Xiong Y, Zhu S, Wang Y, Knobf M, Ye Z. Integrating the symptom experience and coping in patients with stage I-III breast cancer in China: A qualitative study. European Journal Of Oncology Nursing 2024, 73: 102692. PMID: 39406178, DOI: 10.1016/j.ejon.2024.102692.Peer-Reviewed Original ResearchConceptsStage I-III breast cancerI-III breast cancerSymptom experienceBreast cancerPurposive sample of womenSemi-structured interview guideFramework analysis methodSample of womenTranscribed verbatimQualitative descriptive approachBreast cancer treatmentInterview guidePsychological symptomsEarly survivorshipQualitative studyAudio-recordedMultiple symptomsPurposive samplingDescriptive approachAverage ageThemesWomenPersonal interviewsBreastSymptomsNavigating Specific Targets of Breast Cancer Symptoms: An Innovative Computer-Simulated Intervention Analysis
Liang M, Pan Y, Cai J, Xiong Y, Liu Y, Chen L, Xu M, Zhu S, Mei X, Zhong T, Knobf M, Ye Z. Navigating Specific Targets of Breast Cancer Symptoms: An Innovative Computer-Simulated Intervention Analysis. European Journal Of Oncology Nursing 2024, 102708. DOI: 10.1016/j.ejon.2024.102708.Peer-Reviewed Original ResearchConceptsBreast cancer symptomsBreast cancerMD Anderson Symptom InventoryCross-sectional surveySymptoms of distressCancer symptomsPreventive careSymptom impactSymptom InventoryActivity levelsOptimal interventionSymptom interactionsInterventionDisturbed sleepDistressBreastFatigueCancerSymptomsCareIntervention analysisParticipantsSurveyShort-SleepParent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer
Ouyang N, Baker J, Ananth P, Knobf M, Snaman J, Feder S. Parent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer. Journal Of Pain And Symptom Management 2024, 68: 516-524.e1. PMID: 39142495, DOI: 10.1016/j.jpainsymman.2024.08.003.Peer-Reviewed Original ResearchAltmetricConceptsEnd-of-lifeParent-clinician communicationProlonged grief symptomsGrief symptomsChild's end-of-lifeCross-sectional survey of parents of childrenEnd-of-life careHigh-quality end-of-lifeProlonged griefSum scoreSurvey of parents of childrenCross-sectional surveyParents of childrenAdequate prognostic informationBereaved parentsPrognostic informationChild deathsParents' experiencesMultiple linear regressionPG-13Analyzed dataLinear regressionAssociationGriefChildrenBody image, self-efficacy, and sleep quality among patients with breast cancer: A latent profile and mediation analysis
Li S, Xiang Y, Li H, Yang C, He W, Wu J, Knobf M, Ye Z. Body image, self-efficacy, and sleep quality among patients with breast cancer: A latent profile and mediation analysis. European Journal Of Oncology Nursing 2024, 71: 102652. PMID: 38968669, DOI: 10.1016/j.ejon.2024.102652.Peer-Reviewed Original ResearchCitationsConceptsSelf-efficacySleep qualityBody imageGeneral Perceived Self-Efficacy ScaleBreast cancerPittsburgh Sleep Quality Index scaleMediation analysisBreast cancer programBody image distressPromote self-efficacyBody Image ScaleSelf-Efficacy ScaleEffective coping strategiesMediation effect of self-efficacyBody image groupsLatent profile analysisImpact of body imageEffect of self-efficacyCancer programsCoping strategiesIndex scaleBreastNegative impactImage scaleMediation effectBrain Connectomics Improve the Prediction of High‐Risk Depression Profiles in the First Year following Breast Cancer Diagnosis
Liang M, Chen P, Tang Y, Tang X, Molassiotis A, Knobf M, Liu M, Hu G, Sun Z, Yu Y, Ye Z. Brain Connectomics Improve the Prediction of High‐Risk Depression Profiles in the First Year following Breast Cancer Diagnosis. Depression And Anxiety 2024, 2024: 1-11. DOI: 10.1155/2024/3103115.Peer-Reviewed Original ResearchCitationsConceptsBreast cancer diagnosisLatent growth mixture modelingMultivoxel pattern analysisDepression profilesCancer diagnosisBrain connectomeBaseline resting-state functional magnetic resonance imagingResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingAssessment of depressionFrontal medial cortexBrain connectivity patternsGrowth mixture modelingDepression trajectoriesFrontal poleBrain areasRs-fMRIBreast cancerConnectivity patternsHigh riskLow riskBrainConnectomeMagnetic resonance imagingMedial cortexParenting experiences and outcomes among former adolescent mothers: A mixed methods study
Flaherty S, Knobf M, Holland M, Slade A, Nelson L, Sadler L. Parenting experiences and outcomes among former adolescent mothers: A mixed methods study. PLOS ONE 2024, 19: e0303119. PMID: 38748745, PMCID: PMC11095697, DOI: 10.1371/journal.pone.0303119.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMixed methods studyParenting outcomesRandomized clinical trialsAdolescent mothersMethods studyParents' experiencesSequential mixed methods studyExplanatory sequential mixed methods studyHome visiting programsPositive parenting outcomesPhase involved interviewsVisiting programsParticipants' experiencesChild behavior problemsPromote personal growthParticipants 2Maternal experienceQuantitative phaseQualitative dataPersonal growthEarly adulthoodBehavior problemsMothersHostile parentingOutcomesSymptom network approach for management in cancer care
Liang M, Zhu S, Zhang W, Knobf M, Ye Z. Symptom network approach for management in cancer care. Asia-Pacific Journal Of Oncology Nursing 2024, 11: 100482. PMID: 38694967, PMCID: PMC11061680, DOI: 10.1016/j.apjon.2024.100482.Peer-Reviewed Original ResearchSentinel and networked symptoms in patients with breast cancer undergoing chemotherapy
Liang M, Zhong T, Knobf M, Chen L, Xu M, Cheng B, Pan Y, Zhou J, Ye Z. Sentinel and networked symptoms in patients with breast cancer undergoing chemotherapy. European Journal Of Oncology Nursing 2024, 70: 102566. PMID: 38513452, DOI: 10.1016/j.ejon.2024.102566.Peer-Reviewed Original ResearchCitationsConceptsBreast cancer receiving chemotherapyCancer receiving chemotherapyLack of appetiteSymptom clustersSentinel symptomCommunity levelBreast cancerGastrointestinal symptom clusterMD Anderson Symptom InventoryCross-sectional surveyDisturbed sleepBridge symptomsTargeting fatigueExploratory factor analysisSymptom InventoryFactor analysisBreastSymptomsFatigueDiverse symptomsPatientsCommunityCancerSleepDistressPerspectives of Patients With Relapsed and Refractory Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome on Patient–Clinician Communication About Prognosis and the Future
Rao V, Linsky S, Knobf M. Perspectives of Patients With Relapsed and Refractory Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome on Patient–Clinician Communication About Prognosis and the Future. Palliative Medicine Reports 2024, 5: 53-62. PMID: 38249836, PMCID: PMC10797310, DOI: 10.1089/pmr.2023.0064.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPatient-clinician communicationHigh-risk myelodysplastic syndromeAcute myeloid leukemiaPerspectives of patientsMyelodysplastic syndromeU.S. cancer centersSemi-structured interviewsFog of uncertaintyMaintaining normalityDisease trajectoryMyeloid leukemiaPrognostic uncertaintyThematic analysisQualitative studyParticipants' perspectivesR/R acute myeloid leukemiaRefractory acute myeloid leukemiaCancer CenterLived experienceDay-to-day lived experiencesParticipantsHigh riskInterviewsHealthCommunication strategiesAssociations Between Brain Structural Connectivity and 1‐Year Demoralization in Breast Cancer: A Longitudinal Diffusion Tensor Imaging Study
Liang M, Chen P, Tang Y, Liang Y, Li S, Hu G, Sun Z, Yu Y, Molassiotis A, Knobf M, Ye Z. Associations Between Brain Structural Connectivity and 1‐Year Demoralization in Breast Cancer: A Longitudinal Diffusion Tensor Imaging Study. Depression And Anxiety 2024, 2024 DOI: 10.1155/2024/5595912.Peer-Reviewed Original ResearchCitationsConceptsInferior fronto-occipital fasciculusBreast cancerIntegrated discrimination improvementDiagnosed breast cancerIncremental predictive valueDiffusion tensor imagingQuantitative anisotropyPredictive valueDiffusion tensor imaging studiesDemoralization Scale-IIFronto-occipital fasciculusWhite matter tractsSelf-reported dataImaging studiesDiscrimination improvementLongitudinal diffusion tensor imaging studyCancerPatientsCorrelational tractographyNeural pathwaysBrain structural connectivityTensor imagingLongitudinal programBreastScale II
Clinical Trials
Current Trials
The Recovery in Stroke Using PAP Study (RISE-UP)
HIC ID2000024512RoleSub InvestigatorPrimary Completion Date01/31/2024Recruiting ParticipantsGenderBothAge18+ years
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