2023
PO83 Utilization of a Virtual Clinical Trial to Characterize Sensitivity of the Linear-Quadratic Model
Tien C, Draeger E, Guan F, Carlson D, Chen Z. PO83 Utilization of a Virtual Clinical Trial to Characterize Sensitivity of the Linear-Quadratic Model. Brachytherapy 2023, 22: s110. DOI: 10.1016/j.brachy.2023.06.184.Peer-Reviewed Original ResearchTumor control probabilityClinical trialsLinear-quadratic modelNumber of patientsPatient cohort sizeTCP curvesRadiobiological parametersVirtual clinical trialsGy-1Cohort sizeRange of dosesPatient outcomesReference cohortPatientsHeterogeneous cohortVirtual patientsNew trialsRadiobiological parameter valuesClonogenic populationPatient ordersControl probabilityGyInput model parametersTrialsCohort
2017
HDR Monotherapy in Prostate Cancer: Radiobiological Considerations When Determining Biologically Effective Dose in Clinical Trials
Tien C, Carlson D, Nath R, Chen Z. HDR Monotherapy in Prostate Cancer: Radiobiological Considerations When Determining Biologically Effective Dose in Clinical Trials. Brachytherapy 2017, 16: s31. DOI: 10.1016/j.brachy.2017.04.038.Peer-Reviewed Original Research
2013
Using Skin Dose Parameters Predicts Low Skin Toxicity in a Phase 2 Trial of Multiple Dwell Position Balloon-Based Brachytherapy for Partial Breast Irradiation
Nath S, Chen Z, Rowe B, Blitzblau R, Aneja S, Grube B, Horowitz N, Weidhaas J. Using Skin Dose Parameters Predicts Low Skin Toxicity in a Phase 2 Trial of Multiple Dwell Position Balloon-Based Brachytherapy for Partial Breast Irradiation. International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s213. DOI: 10.1016/j.ijrobp.2013.06.551.Peer-Reviewed Original Research
2006
2052 A Phase II Trial of Mammosite Breast Brachytherapy Optimization in the Treatment of Stage 0, I and II Breast Carcinoma
Weidhaas J, Ponn T, Chen Z, Martel M, Zelterman D. 2052 A Phase II Trial of Mammosite Breast Brachytherapy Optimization in the Treatment of Stage 0, I and II Breast Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2006, 66: s239. DOI: 10.1016/j.ijrobp.2006.07.455.Peer-Reviewed Original Research