2023
Dose prescription and reporting in stereotactic body radiotherapy: A multi-institutional study
Das I, Yadav P, Andersen A, Chen Z, Huang L, Langer M, Lee C, Li L, Popple R, Rice R, Schiff P, Zhu T, Abazeed M. Dose prescription and reporting in stereotactic body radiotherapy: A multi-institutional study. Radiotherapy And Oncology 2023, 182: 109571. PMID: 36822361, PMCID: PMC10121952, DOI: 10.1016/j.radonc.2023.109571.Peer-Reviewed Original ResearchConceptsDose prescriptionTreatment-related toxicityClinical outcome comparisonStereotactic body radiotherapyMulti-institutional studyTreatment guidelinesTreatment disparitiesBody radiotherapyPTV volumeClinical trialsTreatment protocolOutcome comparisonsTreatment efficacyAbstractTextHypofractionated treatmentDosimetric parametersDose parametersDosimetric variabilityDosimetric variationsStandardized reportingLack of standardizationPreliminary dosimetric comparison between fixed and rotating source stereotactic radiosurgery systems
Draeger E, Chen Z, Hansen J, Chiang V, Tien C. Preliminary dosimetric comparison between fixed and rotating source stereotactic radiosurgery systems. Journal Of Applied Clinical Medical Physics 2023, 24: e13907. PMID: 36660774, PMCID: PMC10161057, DOI: 10.1002/acm2.13907.Peer-Reviewed Original ResearchConceptsConformity indexRadiation Therapy Oncology Group conformity indexGK plansSuperior conformity indexNon-metastatic casesPaddick conformity indexDosimetric plan qualityGK patientsBrain metastasesRadiosurgery systemTrigeminal neuralgiaPrescription dosesGamma Knife systemMetastatic casesArteriovenous malformationsPituitary adenomasConformality indexLarge cohortDosimetric comparisonStereotactic radiosurgery systemGK IconPatientsCohortTreatment timeDosimetric results
2020
Associating dose–volume characteristics with theoretical radiobiological metrics for rapid Gamma Knife stereotactic radiosurgery plan evaluation
Tien CJ, Bond JE, Chen Z. Associating dose–volume characteristics with theoretical radiobiological metrics for rapid Gamma Knife stereotactic radiosurgery plan evaluation. Journal Of Applied Clinical Medical Physics 2020, 21: 132-140. PMID: 32910543, PMCID: PMC7592963, DOI: 10.1002/acm2.13018.Peer-Reviewed Original Research
2017
Dose-Volume Predictors of Esophagitis After Thoracic Stereotactic Body Radiation Therapy
Harder EM, Chen Z, Park HS, Mancini BR, Decker RH. Dose-Volume Predictors of Esophagitis After Thoracic Stereotactic Body Radiation Therapy. American Journal Of Clinical Oncology 2017, 40: 477-482. PMID: 26017483, DOI: 10.1097/coc.0000000000000195.Peer-Reviewed Original ResearchConceptsStepwise selection techniqueRadiation therapyThoracic stereotactic body radiation therapyStereotactic hypofractionated radiation therapyStereotactic body radiation therapyDose-volume predictorsNormal tissue complication probabilityHypofractionated radiation therapyMultivariate logistic regressionProbability estimatesBody radiation therapyPlanning target volumeEsophageal toxicityEsophagitis ratesCTCAE v4.0Dosimetric predictorsPulmonary tumorsInstitutional databaseRadiotherapy parameters
2016
Pulmonary dose-volume predictors of radiation pneumonitis following stereotactic body radiation therapy
Harder EM, Park HS, Chen Z, Decker RH. Pulmonary dose-volume predictors of radiation pneumonitis following stereotactic body radiation therapy. Practical Radiation Oncology 2016, 6: e353-e359. PMID: 27156424, DOI: 10.1016/j.prro.2016.01.015.Peer-Reviewed Original ResearchConceptsMean lung doseStereotactic body radiation therapyRisk of gradeRadiation pneumonitisMultivariable logistic regressionBody radiation therapyDosimetric predictorsRadiation therapyMaximum doseLogistic regressionRP rateBest dosimetric predictorCardiac dosimetric parametersDose-volume predictorsPercent of lungVolume of lungGross tumor volumeBackward stepwise eliminationLung V10Lung doseMean doseTotal lungUnivariate analysisPulmonary volumesTumor volume