2006
Interleukin 5 Plays an Essential Role in Elicitation of Contact Sensitivity through Dual Effects on Eosinophils and B-1 Cells
Itakura A, Kikuchi Y, Kouro T, Ikutani M, Takaki S, Askenase PW, Takatsu K. Interleukin 5 Plays an Essential Role in Elicitation of Contact Sensitivity through Dual Effects on Eosinophils and B-1 Cells. International Archives Of Allergy And Immunology 2006, 140: 8-16. PMID: 16772721, DOI: 10.1159/000092705.Peer-Reviewed Original ResearchConceptsElicitation of CSIgM-producing cellsContact sensitivityEosinophil peroxidase activityEosinophil infiltrationIL-5Antigen-specific immunoglobulin M antibodyCS-effector T cellsEnzyme-linked immunospot assayLocal tissueEffector T cellsRole of interleukinImmunoglobulin M antibodiesIL-5 receptorImmunized ILImmunospot assayContact sensitizationM antibodiesMononuclear cellsDeficient micePolymorphonuclear cellsT cellsImmune responseCell activationInterleukin-5
1976
Cutaneous basophil hypersensitivity uncovered in the cell transfer of classical tuberculin hypersensitivity.
Askenase P. Cutaneous basophil hypersensitivity uncovered in the cell transfer of classical tuberculin hypersensitivity. The Journal Of Immunology 1976, 117: 741-7. PMID: 1085308, DOI: 10.4049/jimmunol.117.3.741.Peer-Reviewed Original ResearchConceptsCell transferIncomplete Freund's adjuvantSkin reactionsCutaneous basophil hypersensitivityGuinea pigsRecipients of cellsNylon wool columnsCell transfer recipientsDelayed skin reactionsT cellsSkin testBasophil responseFreund's adjuvantCellular transferTuberculin hypersensitivitySensitization of recipientsWool columnsBasophil infiltrationHumoral factorsBasophil numbersPassive transferHypersensitivityRecipientsBasophilsDelayed reactionsAntibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs.
Askenase P, Haynes J, Hayden B. Antibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs. The Journal Of Immunology 1976, 117: 216-24. PMID: 932424, DOI: 10.4049/jimmunol.117.1.216.Peer-Reviewed Original ResearchConceptsCutaneous basophil hypersensitivityCutaneous hypersensitivity reactionsGuinea pigsDelayed hypersensitivityBasophil accumulationProduction of B lymphocytesCutaneous basophil hypersensitivity reactionT lymphocytesKeyhole limpet hemocyanin (KLHB lymphocytesIntradermal injectionDonors 1 weekHypersensitive responseHypersensitivity reactionsPigsSerum antibodiesAntibody production of B lymphocytesHypersensitivityBasophil reactionsImmune serumAntibody productionSerum