Elise Wolf, PhD

Dr. Elise Wolf obtained her PhD in Biomedical Sciences from the University of California, San Francisco in 2022. Under the mentorship of Jason Cyster, she described the role of GPR174 in regulating B cell activation and response. She spent a year as a postdoctoral scholar at the Innovative Genomics Institute in Berkeley, CA in David Nguyen's lab. At the IGI, she used CRISPR-Cas9 to introduce variants of unknown significance (VUS) from patients with hemophagocytic lymphohistiocytosis (HLH) into primary human CD8+ T cells and characterize the effect on cellular cytotoxicity. Dr. Wolf matriculated to the Yale School of Medicine in 2023 and looks forward to a career as a physician-scientist. In the Müschen lab, she is using genome editing strategies to dissect migratory signaling pathways in B cells and how they are dysregulated in hematological malignancies.