166P Analysis of circulating tumour DNA for early relapse detection in stage III colorectal cancer after adjuvant chemotherapy
Jacobs S, Sethi H, Kolveska T, George T, Shchegrova S, Tin T, Lee J, Olson A, Renner D, Kalashnikova E, Yothers G, Wolmark N, Pogue-Geile K, Srinivasan A, Kortmansky J, Louie M, Salari R, Zimmermann B, Aleshin A, Allegra C. 166P Analysis of circulating tumour DNA for early relapse detection in stage III colorectal cancer after adjuvant chemotherapy. Annals Of Oncology 2019, 30: v52. DOI: 10.1093/annonc/mdz239.074.Peer-Reviewed Original ResearchRelapse-free survivalCtDNA-negative patientsStage III colorectal cancerCtDNA-positive patientsColorectal cancerCtDNA statusAdjuvant chemotherapyPlasma samplesTumor DNAMajority of relapsesHigher relapse riskEarly relapse detectionNon-relapsing patientsPrimary tumor tissuesLow plasma volumeDifferent tumor typesRelapse casesTumor burdenCtDNA monitoringRelapse riskNateraPatient outcomesRadiological imagingOne-year time framePresence of ctDNA