1979
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus
Lerner M, Steitz J. Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1979, 76: 5495-5499. PMID: 316537, PMCID: PMC411675, DOI: 10.1073/pnas.76.11.5495.Peer-Reviewed Original ResearchConceptsSmall nuclear RNA moleculesNuclear extractsMouse Ehrlich ascites cellsSmall nuclear RNANuclear RNA moleculesSmall nuclear ribonucleoproteinNuclear RNP particlesMammalian nucleiVertebrate speciesNuclear RNANuclear ribonucleoproteinRNA moleculesSystemic lupus erythematosusDifferent polypeptidesEhrlich ascites cellsIdentical complementSpecific proteinsMajor polypeptidesRNP particlesMolecular identityPossible functionsNuclear processesNuclear RNPAnti-Sm seraVirtue of association
1968
Identification of the A protein as a structural component of bacteriophage R17
Steitz J. Identification of the A protein as a structural component of bacteriophage R17. Journal Of Molecular Biology 1968, 33: 923-936. PMID: 4178187, DOI: 10.1016/0022-2836(68)90328-8.Peer-Reviewed Original ResearchConceptsA proteinBacteriophage R17Amber mutantsMolecule of histidineProtein monomersProtein productsMajor polypeptidesMolecular weight estimatesStructural componentsPhage particlesR17Non-permissive hostsDefective particlesVirus particlesProteinGel filtrationHistidineCistronMutantsSpheroplastsPolypeptideHostCopies