2023
Three-Dimensional Bioprinting Applications for Bone Tissue Engineering
Maresca J, DeMel D, Wagner G, Haase C, Geibel J. Three-Dimensional Bioprinting Applications for Bone Tissue Engineering. Cells 2023, 12: 1230. PMID: 37174630, PMCID: PMC10177443, DOI: 10.3390/cells12091230.Peer-Reviewed Original ResearchConceptsBone tissue engineeringThree-dimensional (3D) bioprinting applicationsTissue engineeringSupport structureAdditional support structuresUse of hydrogelsBioprinting applicationsBone replacementNormal bone physiologyQuality of lifeBioprintingKey support structuresBone physiologyInjurySkeletal systemEngineeringMultiple directionsBiological materialsForeign objectsHydrogelsNew techniquePrinterPatientsPathophysiologyDegeneration
2022
3D Bioprinting Using Hydrogels: Cell Inks and Tissue Engineering Applications
Dell A, Wagner G, Own J, Geibel J. 3D Bioprinting Using Hydrogels: Cell Inks and Tissue Engineering Applications. Pharmaceutics 2022, 14: 2596. PMID: 36559090, PMCID: PMC9784738, DOI: 10.3390/pharmaceutics14122596.Peer-Reviewed Original ResearchTissue engineering applicationsPrintable formulationsBioprinting processEngineering applicationsProcess optimizationBioprinting methodInk formulationTissue engineeringTailorable materialsBioprintingBiomedical applicationsBiological tissuesHydrogelsNew hydrogelsInkPromising optionNovel methodApplicationsBiological applicationsFormulationVariety of techniquesEngineeringMethodMaterials
2021
3D Bioprinting of Vascularized Tissues for in vitro and in vivo Applications
Chen EP, Toksoy Z, Davis BA, Geibel JP. 3D Bioprinting of Vascularized Tissues for in vitro and in vivo Applications. Frontiers In Bioengineering And Biotechnology 2021, 9: 664188. PMID: 34055761, PMCID: PMC8158943, DOI: 10.3389/fbioe.2021.664188.Peer-Reviewed Original ResearchThree-dimensional (3D) bioprinting technologyFunctional replacement organsBioprinting technologyTissue engineeringWaste disposalBioprintingVascularized tissuesComplex tissue architectureRelevant applicationsOrgan replacementLatest advancementsComplex vascular networkMaterialsApplicationsReplacement organsCurrent limitationsMain challengesNumerous combinationsTechnologyRapid developmentEngineeringVascular networkVivo applications
2016
3D Printing of Organs for Transplantation: Where Are We and Where Are We Heading?
Munoz-Abraham A, Rodriguez-Davalos M, Bertacco A, Wengerter B, Geibel J, Mulligan D. 3D Printing of Organs for Transplantation: Where Are We and Where Are We Heading? Current Transplantation Reports 2016, 3: 93-99. DOI: 10.1007/s40472-016-0089-6.Peer-Reviewed Original Research
2015
Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium
McNeer NA, Anandalingam K, Fields RJ, Caputo C, Kopic S, Gupta A, Quijano E, Polikoff L, Kong Y, Bahal R, Geibel JP, Glazer PM, Saltzman WM, Egan ME. Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium. Nature Communications 2015, 6: 6952. PMID: 25914116, PMCID: PMC4480796, DOI: 10.1038/ncomms7952.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineChloridesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDNA-Binding ProteinsGenetic TherapyHigh-Throughput Nucleotide SequencingHumansLactic AcidMice, Inbred C57BLNanoparticlesPeptide Nucleic AcidsPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerPolymersRespiratory MucosaConceptsFacile genome engineeringVivo gene deliveryBiodegradable polymer nanoparticlesTransient gene expressionNanoparticle systemsGene deliveryPolymer nanoparticlesGene correctionGenome engineeringNanoparticlesOff-target effectsPeptide nucleic acidLethal genetic disorderNucleic acidsDonor DNATarget effectsIntranasal deliveryDeliveryCystic fibrosisEngineeringOligonucleotideChloride effluxHuman cellsAirway epitheliumLung tissue