2005
Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland
Hens JR, Wysolmerski JJ. Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland. Breast Cancer Research 2005, 7: 220. PMID: 16168142, PMCID: PMC1242158, DOI: 10.1186/bcr1306.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMammary gland developmentEmbryonic mammary glandGland developmentMolecular mechanismsEmbryonic mammary gland developmentMammary glandProtein signalingMore genesFibroblast growth factorSignaling pathwaysFunctional roleGrowth factorWntGenesKey stagesSignalingMesenchymePathwayMechanismGlandEpidermisDevelopment
2004
Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis
Chu EY, Hens J, Andl T, Kairo A, Yamaguchi TP, Brisken C, Glick A, Wysolmerski JJ, Millar SE. Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development 2004, 131: 4819-4829. PMID: 15342465, DOI: 10.1242/dev.01347.Peer-Reviewed Original ResearchConceptsMammary gland morphogenesisPlacode developmentGland morphogenesisCanonical WntEmbryonic mammary developmentMammary placode formationHair follicle formationSkin appendage morphogenesisWnt pathway activityAdditional WntAppendage morphogenesisWnt signalsPlacode formationWnt genesMolecular controlMammary morphogenesisMammary placodesUnderlying mesenchymeMorphogenesisWnt pathwayWntPathway activityWnt inhibitor Dickkopf-1PlacodeElevated expression