2024
Impact of Synthetic PET Evaluation prior to PET-Guided Functional Modeling in Optimizing Patient Selection for Biology-Guided Radiotherapy
Hicks D, Chen H, Kim J, Tressel L, Wallington D, Becht K, Johung K, Young M, Feghali K, de Jong D, Chen Z, Carlson D, Park H. Impact of Synthetic PET Evaluation prior to PET-Guided Functional Modeling in Optimizing Patient Selection for Biology-Guided Radiotherapy. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: s162-s163. DOI: 10.1016/j.ijrobp.2024.07.2188.Peer-Reviewed Original ResearchPlanning target volumeInternal target volumeBiology-guided radiotherapyStereotactic body radiotherapyGross tumor volumeTarget volumeCT simulationOptimal patient selectionPET evaluationStereotactic body radiotherapy planLung target volumesPatient selectionPTV edgesLung casesBgRTPET-CTTumor sizeTumor volumeRadiotherapyCase 2PET dataLungActivity concentrationsPatientsConsistent with results
2022
Dosimetric Parameters are Associated with Local Control after SBRT for Colorectal Cancer Lung Metastases
Laird J, Mokhtech M, Johung K, Park H, Jethwa K. Dosimetric Parameters are Associated with Local Control after SBRT for Colorectal Cancer Lung Metastases. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e431-e432. DOI: 10.1016/j.ijrobp.2022.07.1640.Peer-Reviewed Original ResearchCRC lung metastasesInternal target volumeLung metastasesLocal controlPrescription dosesUnivariate analysisPrescription doseCox proportional hazards regression modelColorectal cancer lung metastasesProportional hazards regression modelsDosimetric parametersRetrospective cohort studyFavorable local controlImproved local controlLocal treatment optionsSingle cancer centerKaplan-Meier methodHazards regression modelsTarget volume dosesMATERIAL/METHODSMetastasis sizePTV D90Dosimetric predictorsMedian doseCohort studyImpact of Dosimetric Parameters on Local Control after SBRT for Pancreatic Cancer
Oh P, Laird J, Johung K. Impact of Dosimetric Parameters on Local Control after SBRT for Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e197. DOI: 10.1016/j.ijrobp.2022.07.1113.Peer-Reviewed Original ResearchStereotactic body radiotherapyInternal target volumeUnivariate regression analysisGross tumor volumeOverall survivalLocal controlPancreatic cancerPerformance statusSBRT plansTarget volumeCox proportional hazards modelDosimetric parametersAdvanced unresectable diseaseImproved local controlRetrospective cohort studyUse of chemotherapyGood local controlKaplan-Meier methodPancreatic cancer patientsTarget volume sizeProportional hazards modelHigher gross tumor volumeMATERIAL/METHODSComprehensive dosimetric analysisUnresectable disease