1997
Evidence for the Presence of Regional Differences in the Subtype Specificity of Muscarinic Receptors in Rabbit Lower Urinary Tract
Mutoh S, Latifpour J, Saito M, Weiss R. Evidence for the Presence of Regional Differences in the Subtype Specificity of Muscarinic Receptors in Rabbit Lower Urinary Tract. Journal Of Urology 1997, 157: 717-721. PMID: 8996405, DOI: 10.1016/s0022-5347(01)65257-1.Peer-Reviewed Original ResearchConceptsCarbachol-induced contractile responsesBladder baseContractile responseBladder domeMuscarinic antagonistMuscarinic receptorsUrinary tractReceptor subtypesRabbit Lower Urinary TractSubtype-selective muscarinic antagonistsSubtype specificityContractile response curvesM2 receptor subtypeM3 receptor subtypeLower Urinary TractMuscarinic cholinergic receptorsMuscarinic cholinergic antagonistSelective muscarinic antagonistsConcentrations of carbacholTerms of efficacyCholinergic antagonistsCholinergic receptorsPA2 valuesAntagonist affinityUrethra
1994
Diabetes-Induced Alterations in the Properties of Muscarinic Cholinergic Receptors in Rat Vas Deferens
Kamai T, Fukumoto Y, Gousse A, Yoshida M, Davenport T, Weiss R, Latifpour J. Diabetes-Induced Alterations in the Properties of Muscarinic Cholinergic Receptors in Rat Vas Deferens. Journal Of Urology 1994, 152: 1017-1021. PMID: 8051725, DOI: 10.1016/s0022-5347(17)32646-0.Peer-Reviewed Original ResearchConceptsMuscarinic cholinergic receptorsRat vasVas deferensCholinergic receptorsMuscarinic receptorsDiabetic insulin-treated ratsMuscarinic cholinergic receptor subtypesMuscarinic cholinergic receptor densityMembrane particulatesCholinergic receptor densityDiabetes-Induced AlterationsAF-DX 116Cholinergic receptor subtypesMuscarinic cholinergic antagonistAdministration of insulinInsulin-treated ratsAge-matched controlsRat vas deferensRank orderAdditional pharmacological studiesDiabetic ratsBladder domeCerebral cortexCholinergic antagonistsReceptor subtypes
1991
Muscarinic receptors in diabetic rat prostate
Latifpour J, Gousse A, Yoshida M, Weiss R. Muscarinic receptors in diabetic rat prostate. Biochemical Pharmacology 1991, 42: s113-s119. PMID: 1768268, DOI: 10.1016/0006-2952(91)90400-y.Peer-Reviewed Original ResearchConceptsMuscarinic receptorsRat prostateM3 muscarinic receptor subtypesMembrane particulatesAF-DX 116Injection of streptozotocinMuscarinic cholinergic receptorsMuscarinic receptor subtypesSTZ-induced diabetesM3 muscarinic receptorsDiabetic rat prostateLower body weightGroups of ratsInsulin-treated animalsVariety of abnormalitiesDiabetic insulinMuscarinic antagonistSmaller prostatesCholinergic receptorsReceptor subtypesPharmacological profileBody weightFmol/Myo-inositolDiabetes
1987
Ureteral Urine Transport: Changes in Bolus Volume, Peristaltic Frequency, Intraluminal Pressure and Volume of Flow Resulting from Autonomic Drugs
Morita T, Wada I, Saeki H, Tsuchida S, Weiss R. Ureteral Urine Transport: Changes in Bolus Volume, Peristaltic Frequency, Intraluminal Pressure and Volume of Flow Resulting from Autonomic Drugs. Journal Of Urology 1987, 137: 132-135. PMID: 3795356, DOI: 10.1016/s0022-5347(17)43904-8.Peer-Reviewed Original ResearchConceptsUreteral peristaltic frequencyPeristaltic frequencyContractile pressureBolus volumeIntraluminal pressureAutonomic nervous systemAutonomic agonistsAutonomic drugsNervous systemBaseline pressureExperimental modelSmall decreaseUrine transportBaselineResultant decreaseBolus formationFlow volumeElevationFluid transportNorepinephrineAcetylcholineDecreaseUreterAgonistsIsoproterenol