Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer
Nicolas E, Arora S, Zhou Y, Serebriiskii I, Andrake M, Handorf E, Bodian D, Vockley J, Dunbrack R, Ross E, Egleston B, Hall M, Golemis E, Giri V, Daly M. Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer. Oncotarget 2015, 6: 39614-39633. PMID: 26485759, PMCID: PMC4741850, DOI: 10.18632/oncotarget.5554.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic Agents, PhytogenicCells, CulturedDNA Breaks, Double-StrandedDNA RepairEtoposideExomeFamily HealthGenetic Predisposition to DiseaseHistonesHumansINDEL MutationMaleMiddle AgedMutationPolymorphism, Single NucleotideProstatic NeoplasmsRisk AssessmentRisk FactorsSequence Analysis, DNAT-LymphocytesConceptsDNA repairGenes of relevanceDNA damage responseDNA damaging agentsDNA double strand break marker γH2AXDamage responseGene variants