2024
Thursday, July 11, 20244:00 PM - 5:00 PM PP01 Presentation Time: 4:00 PM Investigating Shielding as a Dose-Shaping Tool in Flattening Distal Dose Profiles for Single-Channel Vaginal Cylinders
Tien C, Mullane S, Draeger E, Rivard M, Chen Z. Thursday, July 11, 20244:00 PM - 5:00 PM PP01 Presentation Time: 4:00 PM Investigating Shielding as a Dose-Shaping Tool in Flattening Distal Dose Profiles for Single-Channel Vaginal Cylinders. Brachytherapy 2024, 23: s26-s27. DOI: 10.1016/j.brachy.2024.08.020.Peer-Reviewed Original ResearchModel-based dose calculation algorithmsSingle-channel vaginal cylinderDose profilesDose distributionVaginal cylinderCentral axisCustomized shieldingRegions of high doseAnisotropic dose distributionUniform dose profileDose calculation algorithmWater-equivalent materialDose calculation methodMonte CarloIr-192 seedsDose gridIr-192MC simulationsRelative doseShielding materialsCalculation algorithmSource transitionDose optimizationLateral radiusShieldingPO0116 Design and Characterization of a Brachytherapy Applicator with Modulated Shielding (MOSH) for the Treatment of Cervical Cancer
Schwipper C, Mullane S, Draeger E, Chen Z, Rivard M, Tien C. PO0116 Design and Characterization of a Brachytherapy Applicator with Modulated Shielding (MOSH) for the Treatment of Cervical Cancer. Brachytherapy 2024, 23: s92. DOI: 10.1016/j.brachy.2024.08.134.Peer-Reviewed Original ResearchDose distributionBrachytherapy applicationsOAR dosesIr-192TG-43 dose calculation formalismShield geometryReduces dose to OARAAPM TG-43 formalismShielding materialsDose calculation formalismHigh-Z shieldingReduced OAR dosesCalculated dose distributionsTG-43 formalismDose-volume objectivesDose to OARsTreatment of cervical cancerHDR brachytherapy applicatorsHigh-risk clinical target volumeIr-192 sourceImproved dose distributionClinical target volumeSparing OARsTOPAS MCYb-169
2022
Skin dose distributions between Stanford and rotational techniques in total skin electron therapy (TSET)
Ding G, Chen Z, Zhong W, Zhu T. Skin dose distributions between Stanford and rotational techniques in total skin electron therapy (TSET). Medical Physics 2022, 49: 6646-6653. PMID: 35972019, DOI: 10.1002/mp.15907.Peer-Reviewed Original ResearchConceptsTotal skin electron therapyDose coverageStanford techniqueAdvanced-stage cutaneous T-cell lymphomaCutaneous T-cell lymphomaSkin dose distributionRotational techniqueT-cell lymphomaPatient's postureSimilar dose coverageDose distributionExtended treatment distancesElectron therapyMean doseEffective treatmentSame patientSmall dose differencesClinical settingPatient treatmentSkin dosesRealistic clinical settingsSkin doseDoseDifferent posturesDistribution of dose
2018
Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement
Yan H, Ma X, Sun W, Mendez S, Stryker S, Starr‐Baier S, Delliturri G, Zhu D, Nath R, Chen Z, Roberts K, MacDonald CA, Liu W. Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement. Medical Physics 2018, 45: 4720-4733. PMID: 30133705, DOI: 10.1002/mp.13144.Peer-Reviewed Original ResearchConceptsX-ray beamMC simulation programEye plaque treatmentCentral axis depth doseMC simulationsDose distributionBeam focusingEye Physics plaquesPhantom irradiationDose enhancementEnergy spectrumDepth doseLens modelingDosimetry modelingPhotoelectric absorptionKV rangeKV X-ray beamsBeamEBT3 filmSimulation programEnergy regimeModelingX-ray techniquesHalf maximumMore flexibility
2017
Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions
Tien CJ, Astrahan MA, Kim JM, Materin M, Chen Z, Nath R, Liu W. Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions. Brachytherapy 2017, 16: 1057-1064. PMID: 28778599, DOI: 10.1016/j.brachy.2017.06.014.Peer-Reviewed Original ResearchConceptsEye modelDisc distanceDose differenceTumor apexPrescription doseOcular parametersPlaque SimulatorOcular structuresSubstantial dose differencesTarget volumePlaque positionDosimetric parametersPatientsClinical planningDosimetric impactSignificant differencesBrachytherapy planningSeed strengthPlaquesBrachytherapy dose distributionsDose distributionPatient-specific modelsDifferencesTumorsRetina
2009
AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137
Nath R, Bice WS, Butler WM, Chen Z, Meigooni AS, Narayana V, Rivard MJ, Yu Y. AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137. Medical Physics 2009, 36: 5310-5322. PMID: 19994539, PMCID: PMC2776817, DOI: 10.1118/1.3246613.Peer-Reviewed Original ResearchConceptsBiological equivalent doseTumor volumeDose prescriptionStandard of careProstate cancer patientsPermanent interstitial brachytherapyAcute single dosesEffects of edemaCancer patientsSurgical traumaIntraoperative implantationSingle dosesClinical trialsProstate cancerRadiobiological modelsCurrent recommendationsInterstitial brachytherapyMore specific guidelinesRoutine patient treatmentsDifferent dose distributionsTreatment planPatient treatmentTarget volumeMost implantsDose distributionMonte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases
Deng J, Chen Z, Knisely J, Decker R, Chiang V, Nath R. Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases. IFMBE Proceedings 2009, 25/1: 13-16. DOI: 10.1007/978-3-642-03474-9_4.Peer-Reviewed Original ResearchSpinal metastasesStereotactic radiosurgeryDose-volume histogramsMean doseAnalytical anisotropic algorithmRisk of recurrenceTarget dose coverageDose distributionPencil beam convolutionSpinal cordDose coverageTarget dosePTV doseTreatment planMetastasisHomogeneity indexDoseRadiosurgeryPBC resultsPatientsTreatment planning systemPatient anatomyCommercial treatment planning systemDose discrepanciesAccurate dose distribution
2008
Evaluation of an electron Monte Carlo dose calculation algorithm for electron beams
Hu YA, Song H, Chen Z, Zhou S, Yin F. Evaluation of an electron Monte Carlo dose calculation algorithm for electron beams. Journal Of Applied Clinical Medical Physics 2008, 9: 1-15. PMID: 18716583, PMCID: PMC5722292, DOI: 10.1120/jacmp.v9i3.2720.Peer-Reviewed Original ResearchConceptsElectron Monte Carlo dose calculation algorithmMonte Carlo dose calculation algorithmGrid sizeDose calculation algorithmCalculation grid sizeCalculation algorithmEMC algorithmElectron beamMonte Carlo simulationsElectron beam directionMeasurement dataCutout factorsCalculation iterationsCarlo simulationsDose distributionMeV electron beamLinac headBeam characteristicsBeam dataBeam directionMinimal measurementsMaximum discrepancyAlgorithmDose calculationsBeam
2006
Evaluation of the EDR-2 film for relative dosimetry of high-energy photon and electron beams
Ahmad M, Chen Z, Song H, Deng J, Nath R. Evaluation of the EDR-2 film for relative dosimetry of high-energy photon and electron beams. Radiation Protection Dosimetry 2006, 120: 159-162. PMID: 16644932, DOI: 10.1093/rpd/ncj006.Peer-Reviewed Original ResearchConceptsEDR-2 filmsElectron beamRelative dosimetryHigh-energy photonsClinical radiation dosimetryDose profilesPhotonsRadiation dosimetryBeamDose distributionRadiographic filmsSensitometric studyFilmsDosimetryTreatment planning techniquesElectronsDiodesSymmetryKVFlatnessPlanning techniquesDistribution
2004
Imrt of whole pelvis and inguinal nodes: Evaluation of dose distributions produced by an inverse treatment planning system
Ahmad M, Song H, Moran M, Lund M, Chen Z, Deng J, Haffty B, Nath R. Imrt of whole pelvis and inguinal nodes: Evaluation of dose distributions produced by an inverse treatment planning system. International Journal Of Radiation Oncology • Biology • Physics 2004, 60: s484-s485. DOI: 10.1016/j.ijrobp.2004.07.410.Peer-Reviewed Original ResearchA technique to re-establish dose distributions for previously treated brain cancer patients in external beam radiotherapy
Yue NJ, Knisely JP, Studholme C, Chen Z, Bond JE, Nath R. A technique to re-establish dose distributions for previously treated brain cancer patients in external beam radiotherapy. Medical Dosimetry 2004, 29: 31-41. PMID: 15023391, DOI: 10.1016/j.meddos.2003.09.004.Peer-Reviewed Original ResearchConceptsPrevious treatmentCurrent treatmentTreatment planPrevious treatment sessionTime of reirradiationCurrent treatment planExternal beam radiotherapyBrain cancer patientsNew treatment planPatient coordinate systemDose distributionPatient anatomyCancer patientsTumor recurrenceCurrent patient anatomyBeam radiotherapyNew tumorsTreatment sessionsTreatment dose distributionsIsocenter coordinatesPatient positionNew patient anatomyBrain treatmentCollimator anglesRadiotherapy treatment
1999
Optimum timing for image-based dose evaluation of 125I and 103Pd prostate seed implants
Yue N, Chen Z, Peschel R, Dicker A, Waterman F, Nath R. Optimum timing for image-based dose evaluation of 125I and 103Pd prostate seed implants. International Journal Of Radiation Oncology • Biology • Physics 1999, 45: 1063-1072. PMID: 10571216, DOI: 10.1016/s0360-3016(99)00282-5.Peer-Reviewed Original ResearchConceptsDose-volume histogramsProstate volumeDose coverageConventional dose-volume histogramsSeed implantsEdema magnitudeMagnitude of edemaOptimum timingPostimplant dose-volume histogramDose evaluationOptimal patient managementProstate seed implantationPreimplant planImplant patientsPermanent brachytherapy implantsProstate seed implantsPatient managementProstate cancerSeed implantationSurgical proceduresEdemaProstateDose distributionDays postimplantationPatients