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Smilow and Yale Cancer Center Town Hall | October 2021

October 08, 2021
  • 00:00Welcome to and get and our monthly yield.
  • 00:03Cancer Center, Smilow Cancer Hospital,
  • 00:06town hall. It's really good to see all
  • 00:08of you and I hope you're all doing well.
  • 00:11If you can rename,
  • 00:12move to the next slide please.
  • 00:14OK, so as you know we had the
  • 00:17closer to free right again.
  • 00:18Unfortunately it was virtual,
  • 00:20but the good part is, as always,
  • 00:23the teams were unstoppable
  • 00:24and we raised over two.
  • 00:27There were 2000 writers from 30 States
  • 00:30and two countries and we raised over
  • 00:332.1 million hospital to support Cancer
  • 00:35Research and patient care at both.
  • 00:37Are y'all Cancer Center and smile oh
  • 00:39cancer hospital so thank you to all
  • 00:41who participated and also to all of
  • 00:43our teams outstanding and what a great.
  • 00:46Picture next slide.
  • 00:48K.
  • 00:48As you know,
  • 00:49we usually talk about sort of new
  • 00:50announcements and new folks who joined.
  • 00:52So these are like all great stuff
  • 00:54in terms of new announcements.
  • 00:56This is sort of somewhat bittersweet.
  • 00:57Doctor James you you've met
  • 00:59previously is leaving our institution,
  • 01:02but it's I'm excited to announce
  • 01:03Dr Lynn Wilson,
  • 01:04who has presented at this town hall
  • 01:06before as our Deputy Chief Medical
  • 01:09Officer for Radiation Oncology.
  • 01:11So welcome Doctor Wilson in your new role.
  • 01:13Also in another announcement,
  • 01:15Margaret Gill Shannon, who is been.
  • 01:17Working with us and the Yale
  • 01:19Cancer Center joined the Yale
  • 01:21Cancer Center about a year ago.
  • 01:23As our director of Senior Director,
  • 01:25Finance and Administration,
  • 01:27and his was also leading the
  • 01:29integrated business operations for
  • 01:31the Department of Pathology that
  • 01:33we recently appointed as our Deputy
  • 01:35Director of Finance and Administration.
  • 01:37In that role,
  • 01:38Margaret will be overseeing all the
  • 01:40various facets or clinical operations,
  • 01:42business finance, research,
  • 01:44management and clinical trials.
  • 01:46Take most of you know Margaret are ready,
  • 01:48but if you haven't.
  • 01:49You will be meeting her soon
  • 01:51and she's been now.
  • 01:52She's 100% as part of her team and we're
  • 01:55really excited to make that happen.
  • 01:58Uhm,
  • 01:58we talk a lot about clinical
  • 02:00trials and also about how this
  • 02:02is important for our patients,
  • 02:04but also our physicians and our teams.
  • 02:07And this is a big entity and making
  • 02:09this make sure that all of the parts
  • 02:12aligned together means that the cancer,
  • 02:14the CTO director really needs a team and
  • 02:18it's really nice to see the team expands.
  • 02:21So we have announced 2 new roles
  • 02:23and Assistant medical director
  • 02:24for the Clinical Trials Office
  • 02:26for Smilow Cancer Hospital.
  • 02:28And another one for care center
  • 02:30networks or doctor Stacy sign has
  • 02:32stepped in as our system medical
  • 02:34director for the Clinical Trials
  • 02:36Office for the Cancer Hospital
  • 02:38and then Doctor Neo Fishback.
  • 02:40We think most of you know is the
  • 02:43is for our care center network.
  • 02:44So congratulations to both of them.
  • 02:47The search committee.
  • 02:48I thank the search committee for
  • 02:50all their hard work and helping
  • 02:52us pick two great leaders.
  • 02:54New appointments starting
  • 02:55September of this year.
  • 02:57Doctor Christy Kim.
  • 02:58Has joined us as Assistant Professor of
  • 03:01Clinical Medicine and joined the Smilow
  • 03:04Cancer Hospital Care Center in Waterford.
  • 03:06She starts on November 22nd and Doctor
  • 03:08Kim is a General Medical oncologist.
  • 03:11But I've met her and she has a special
  • 03:13interest in gynecological cancers,
  • 03:15breast cancers and lymphoma.
  • 03:17Dr Ansley Roach has joined us in in
  • 03:22auto laryngologist in the Department
  • 03:23of Surgery and she cares for patients
  • 03:25with head and neck cancers in both
  • 03:27in New Haven and also our site.
  • 03:29At Trumbull.
  • 03:31And then Doctor Shannon Moore
  • 03:33joins us as assistant professor of
  • 03:36psychiatry focusing on Psycho Oncology
  • 03:38program for our cancer hospital,
  • 03:40and she's also joined by Doctor Jennifer
  • 03:43Quelques, who's also an assistant
  • 03:45professor of psychology psychiatry.
  • 03:46But she focuses on psychological medicine.
  • 03:48So welcome to all of our new
  • 03:51physician leaders. Next slide.
  • 03:53OK, good news in for one of the parts.
  • 03:57I think in connecting all of our missions,
  • 03:59you know we do.
  • 04:00How do we connect?
  • 04:01All of that is all offer amazing research
  • 04:04that happens each and every day.
  • 04:06So Dr Marcus, musician who heads our CMC.
  • 04:09Oh,
  • 04:09which is the Center for Molecular and
  • 04:12Cellular Oncology was recently awarded
  • 04:14this NCI Outstanding Investigator award.
  • 04:16This is a huge honor so really
  • 04:19excited and proud of Doctor Mission
  • 04:21and this is a matter of pride
  • 04:23for also of the Cancer Center.
  • 04:25This comes to someone who supports
  • 04:28scientists who really are at the premier
  • 04:31levels of productivity and innovation.
  • 04:33And provides more than 7 million
  • 04:35in funding over seven years for
  • 04:37groundbreaking Cancer Research.
  • 04:39Also excited to mention Doctor
  • 04:41Suchitra Krishnan Sarin,
  • 04:42who's a professor of psychiatry and
  • 04:44a member of her cancer prevention
  • 04:46and Control research program.
  • 04:48She's been appointed to serve on the
  • 04:50steering committee of the New American
  • 04:52Association for Cancer Research,
  • 04:53Research, Cancer Prevention Working Group,
  • 04:56which is dedicated to supporting
  • 04:59cancer prevention research.
  • 05:01More news Doctor Matthew McConnell
  • 05:03was an instructor in medicine as
  • 05:05part of the Digestive diseases Team
  • 05:07and Doctor Sean Go in lab medicine.
  • 05:09Are they normal?
  • 05:10Award?
  • 05:11Ease of the JJ Millstone up
  • 05:13fund to support their project,
  • 05:14which is the role of platelets in
  • 05:17the pathogenesis of alcohol related
  • 05:19liver disease and high throughput.
  • 05:21Diagnostic evaluation of patients with
  • 05:24platelet disorders by my mass cytometry.
  • 05:26So congratulations to all of them.
  • 05:29Renee next slide. More good news.
  • 05:31Doctor Sabrina Browning is who's an
  • 05:34assistant professor in hematology
  • 05:36division has been selected as your
  • 05:39faculty representative to the
  • 05:40Deans Faculty Advisory Council
  • 05:42through October of 2024.
  • 05:44Congratulations and thank you for
  • 05:46serving in this critical role.
  • 05:47Sabrina, I think your faculty chose you.
  • 05:50Your peers chose you as as their
  • 05:53representative doctor Naveed Hafez,
  • 05:55who's in is also an assistant
  • 05:57professor in medical oncology,
  • 05:58has been awarded.
  • 05:59Bristol Myers Squibb Foundation
  • 06:01and National Medical Fellowship.
  • 06:03Diversity in clinical trials.
  • 06:05Career Development award through ACR.
  • 06:07Also, congratulations Naveed.
  • 06:09And then Elizabeth Claus,
  • 06:12who's a professor in Biostatistics
  • 06:13and a member of the cancer Prevention
  • 06:16and Control Research Program,
  • 06:17was appointed a
  • 06:20U2U2C grant from the NCI National
  • 06:23Cancer Institute to support her
  • 06:25proposal optimizing engagement in
  • 06:28discovery of molecular evolution
  • 06:30of low grade glioma or the acronym
  • 06:33OPTIMUM and then last but not least,
  • 06:35Michael Cicchini,
  • 06:36who many of you know was also an
  • 06:38assistant professor in medical oncology.
  • 06:40Just has been awarded a Keyway Career
  • 06:43Development award for his research
  • 06:45and development of two investigator
  • 06:47initiated clinical trials for
  • 06:49patients with colorectal cancer,
  • 06:50under the mentorship of the inevitable.
  • 06:53But Doctor Patricia Lorusso really
  • 06:55outstanding and you can see that the
  • 06:58level of talent and also at all levels,
  • 07:00which is kind of nice to see as a
  • 07:03director that we have people at the
  • 07:05assistant professor in all the way of
  • 07:07senior physicians for getting national award.
  • 07:10So congratulations.
  • 07:10So all of you next slide
  • 07:13part of her cancer centers,
  • 07:14of course,
  • 07:14also our nursing teams and our
  • 07:17other frontline teams.
  • 07:18And we had the Frederick De Luca words.
  • 07:21Those were outstanding.
  • 07:22Leslie DeLuca joined us and we
  • 07:24had 10 be announced.
  • 07:2510 nursing scholarships were awarded to
  • 07:28recipients who are currently enrolled in
  • 07:30an accredited School of Nursing program.
  • 07:32Each of the award ES embraces the
  • 07:35mission and vision of Smilow Cancer
  • 07:37Hospital and demonstrates a commitment
  • 07:40to oncology nursing patient care.
  • 07:42The ability to communicate and
  • 07:44collaborate effectively in a
  • 07:46commitment to lifelong learning.
  • 07:48Think you can see the congratulations
  • 07:49and I have to say the ceremony was
  • 07:51fabulous and I want to thank all the
  • 07:53people who organized that wonderful event.
  • 07:55But the the the Awardee's work here in
  • 07:58London and ambulatory Care Care Associates,
  • 08:01in pediatric hematology oncology.
  • 08:03Noel Kyle,
  • 08:04who's also a PCA in NP12 Kristen White
  • 08:07who's a PC in surgical oncology on MP15.
  • 08:11Delilah Langley frac Franks.
  • 08:12Susan Ambulatory Care Associates
  • 08:14for the women's program.
  • 08:16Yvette Hernandez,
  • 08:17who is in Guilford Martha crack,
  • 08:19who's a patient, services in North Haven.
  • 08:23Arlene Mangione,
  • 08:24who's in practice nurse in Guilford?
  • 08:27Christina Capriotti,
  • 08:27who is in our Greenwich site.
  • 08:30Amanda Kardes,
  • 08:31who does outpatient oncology infusion
  • 08:34in Waterbury and broke Szarmach who
  • 08:37is at helps the centers in Derby,
  • 08:40Waterbury and Torrington.
  • 08:42So congratulations.
  • 08:44To all of our vendors really proud of
  • 08:46you and so glad and I want to thank
  • 08:48Mr Luka for support of this program.
  • 08:50For our trainees.
  • 08:51Alright, that was fast and furious,
  • 08:54but now we have more sort of
  • 08:57a panel discussion today.
  • 08:58First up,
  • 08:59you just heard about the De Luca Awards,
  • 09:02but there's also delucas entrance.
  • 09:04Doctor Stephanie Helene is going
  • 09:05to be giving us a little update
  • 09:07followed by Doctor Jean Kennewick is
  • 09:09going to talk about how do we think
  • 09:11about treating our older patients?
  • 09:12And can we do risk calculators in this
  • 09:15idea of informed decision making?
  • 09:18Doctor Karen Adelson is going to talk
  • 09:19to us a little bit about supply chain.
  • 09:22Issues and then no meeting in recent
  • 09:24months as would be incomplete without
  • 09:26talking about some of the challenges
  • 09:29that we continue to face around capacity.
  • 09:31And of course, as always your very own CMO
  • 09:34doctor Billingsley is joining us as always,
  • 09:36so with that I'm going to turn it over to
  • 09:38Doctor Helene to talk about her center.
  • 09:46Thank you so much,
  • 09:47needle and turn. OK, 'cause
  • 09:49the slides look OK.
  • 09:51Yeah, thank you so much needed for
  • 09:53allowing me to present today so it's a
  • 09:56pleasure to present the DeLuca Center
  • 09:58for Innovation in Hematology research,
  • 10:01which was really a transformative 5 year
  • 10:04grant from the Frederick DeLuca Foundation,
  • 10:07and I have the pleasure to Co
  • 10:10leaders with Michael Smission
  • 10:11about whom you have just heard.
  • 10:14And this five year Grant
  • 10:16focuses on actually five key
  • 10:18aspects for hematology research,
  • 10:21and one is to build a biorepository
  • 10:23and clinical database.
  • 10:24One is the state of the art Malecki
  • 10:27annotation development of novel
  • 10:29technologies Pilot 5 pilot grants per
  • 10:31year to advance hematology research and
  • 10:33one to your career career development
  • 10:36award per year to provide protected
  • 10:38research time to hematology faculty.
  • 10:40We are now just about 2 1/2 years into this.
  • 10:44And let me tell you what we have,
  • 10:46what we have done,
  • 10:47and what we're planning to do.
  • 10:49So we recently had a wonderful internal
  • 10:52Advisory Board meeting with Barbara Burtness.
  • 10:55Peter Glaser practices.
  • 10:56Of course they are Mark Lemon and Pam Kuntz,
  • 10:59and we need to look at what would have
  • 11:02we achieved and where are we going.
  • 11:05There was an amazingly fruitful
  • 11:07compensation and we will have these
  • 11:09meetings on A6 monthly basis to take
  • 11:11us forward in a meaningful way.
  • 11:15And So what have we chief?
  • 11:17So let me tell you about
  • 11:20the hematology tissue bank,
  • 11:21where we're really trying to accrue samples,
  • 11:24collected samples from patients
  • 11:26with all humility, logic disorders,
  • 11:27malignant benign,
  • 11:28and over the last many years we
  • 11:32have collected over 5000 samples
  • 11:34from over 2002 1500 patients,
  • 11:36and I think the first thing here
  • 11:38goes to the patients who are willing
  • 11:40to participate so that we can learn
  • 11:43more about their diseases and
  • 11:44ultimately develop new treatments.
  • 11:46The samples include bone marrow,
  • 11:48preferred blood,
  • 11:49lymph node and tissue biopsies and come.
  • 11:52And during COVID we also started
  • 11:55specialized process or also processing
  • 11:58of COVID samples and will also
  • 12:00provide specialized processing for
  • 12:02clinical trial samples in hematology.
  • 12:05Uhm, database and Sutter repository
  • 12:08is only useful if it can write.
  • 12:11If it's samples can be used and
  • 12:13once you have this many samples it
  • 12:15is really important to have a state
  • 12:18of the art electronic database that
  • 12:20is also accessible to interested
  • 12:23scientists and identified manner
  • 12:25and so currently we're building
  • 12:26this freezer words by repository
  • 12:28database and that is led by Jennifer
  • 12:32Fanwood and Hoven.
  • 12:34And ultimately,
  • 12:35we would like to also build
  • 12:37a red cap clinical database.
  • 12:40We have in the meantime provided
  • 12:4212 pilot grants.
  • 12:43I will show you some examples.
  • 12:44We have aborted one career development
  • 12:47awards and I will show you that too.
  • 12:51We are building a team to provide
  • 12:53Technical Support for correlative
  • 12:55studies and data analysis,
  • 12:57and that includes Jennifer Padma Melanie,
  • 13:00who just recently joined us, Ameesha and Ron.
  • 13:03I have actually moved on to
  • 13:05their next careers.
  • 13:07And we're also working on providing
  • 13:09access to novel technology,
  • 13:11single cell DNA sequencing,
  • 13:13single cell cytokine assays etc.
  • 13:15Uhm and so let me tell you briefly about
  • 13:19the the database progress we're making,
  • 13:23and this is a wonderful
  • 13:25collaboration with Wade Schultz and
  • 13:27laboratory medicine and his team.
  • 13:29And here you see the Freezer
  • 13:32works database with our samples.
  • 13:34The goal to build a Redcap clinical
  • 13:36database and the important thing is that
  • 13:39it's databases don't stand in isolation,
  • 13:42but that they talk to each other and so.
  • 13:45Wade and I can't tell you so
  • 13:47much about this computation.
  • 13:49Has platform bed 'cause it is beyond me,
  • 13:51but wade with his team is building
  • 13:54this amazing central data hub where
  • 13:58all these individual databases
  • 14:00can feed into that.
  • 14:03Ultimately, we can, you know,
  • 14:05learn about patient outcomes mutations,
  • 14:08use samples, than in functional studies,
  • 14:11etc.
  • 14:11And so this is ongoing and I just learned
  • 14:15from Jennifer that there may be a week.
  • 14:17Away from the final import of
  • 14:20all the of the data for all the
  • 14:23samples that we have collected.
  • 14:25Uhm so uhm. Sorry about that.
  • 14:29So again,
  • 14:30I just told you about this
  • 14:32freezer works database on the.
  • 14:33UM,
  • 14:34it's really state of the art data
  • 14:36based on watts and with every iteration
  • 14:39they have improved it and in this.
  • 14:43Version what is very very
  • 14:44interesting to us is that
  • 14:46patients and samples are organized
  • 14:49by studies which may ultimately
  • 14:51also provide some opportunities to
  • 14:54support clinical trials or really
  • 14:56project based on research studies.
  • 14:58We have been very successful in collecting
  • 15:00blood and bone marrow samples and we
  • 15:02have recently created a small team and
  • 15:04we're getting help from these acodec
  • 15:06who's assistant professor and surgery
  • 15:09to expand our acquisition into Internet.
  • 15:13Tissue biopsies,
  • 15:14in particular lymph nodes,
  • 15:15and so Lisa and Jennie grocery in Attalla G,
  • 15:18are teaming up with us to achieve this,
  • 15:22so let me tell you a little bit about the
  • 15:25pilot grants and career development award.
  • 15:27So shelling Kosar is actually our
  • 15:30first career development award.
  • 15:32E&T is particularly interested
  • 15:34in treating mental seven former,
  • 15:36which is a very aggressive lymphoma
  • 15:39and he is devising novel strategies
  • 15:42to activate apoptosis.
  • 15:43And he's mentored by Sam Katz
  • 15:46and Pathology and Marcus Vision.
  • 15:48The other important thing to note
  • 15:50is that these are examples of three
  • 15:52pilot grants we were able to award.
  • 15:54We like team science and what we would
  • 15:56like to do with pilots is to bring in
  • 15:59people who don't normally think about him,
  • 16:01not dermatologic diseases.
  • 16:03And so this is, for example,
  • 16:05a grant.
  • 16:06Withers is Sophie.
  • 16:07In hematology I mean are showing
  • 16:09him pathology and Jordan Pober
  • 16:12and vascular biology.
  • 16:13This pilot here is led by Alex Pine
  • 16:17was interested in COVID with Alfred
  • 16:20Lee and Kilchurn from cardiology
  • 16:22and this is a grant by Monash,
  • 16:24Paula and Kara.
  • 16:25Now current catalog power isn't irony.
  • 16:28Splicing expert in M B&B.
  • 16:34And here's just a list of
  • 16:36additional pilot grants,
  • 16:38so they really spend from basic
  • 16:41science to clinical science and just
  • 16:43show you a couple of results of of
  • 16:47the effect such pilots grandkids have.
  • 16:50So, for example, these are two papers
  • 16:52with the team around Scott Huntington
  • 16:54looking at cost effectiveness of
  • 16:55first line versus third line is broken
  • 16:58up in patients with untreated CLL,
  • 16:59and there's another cost effectiveness
  • 17:01study of looking at second line
  • 17:03use of their tumor mapping.
  • 17:05Older transplant ineligible patients with
  • 17:07multiple myeloma and again this is really
  • 17:11teams coming together with the copper center.
  • 17:13Natalia is my normal
  • 17:16specialist Scott Huntington,
  • 17:17a former specialist whose teams
  • 17:19coming together and the pilot
  • 17:21grants allow us to do this.
  • 17:24And this is our we have given out
  • 17:26three years of pilot grants so far.
  • 17:28And again, here are additional award
  • 17:30design and some of them are more recent,
  • 17:33but I want to highlight
  • 17:35a paper by Alfred Lee,
  • 17:37Anne Shelton and team.
  • 17:39And this is actually from early from
  • 17:42last year describing endothelial apathy
  • 17:45in COVID-19 associated quagga apathy.
  • 17:48And this paper is absolutely amazing,
  • 17:51and you can tell that it has already
  • 17:53been cited by more than 200 and.
  • 17:5580 publications and it really has
  • 17:57very early on in the pandemic,
  • 17:59elucidated some of the mechanisms
  • 18:02of this devastating infection and.
  • 18:05Alfred also end until turn also have
  • 18:07a paper on neutrophil activation
  • 18:09signature that predicts illness
  • 18:10and mortality in COVID-19,
  • 18:12and this incredibly irrelevant as people who,
  • 18:15for example, study immunity,
  • 18:17improve it,
  • 18:18realize that people have different
  • 18:20antibodies that may have different effects
  • 18:23on this beautiful activation signature.
  • 18:25So I just would like everybody to
  • 18:27stay tuned for the call for the
  • 18:30next pilot and CD applications.
  • 18:32We will put out the call.
  • 18:33N1 asked for a letter of intent,
  • 18:35assemble one.
  • 18:36Not that as exclusionary,
  • 18:38but it helps us to understand how
  • 18:40many applications people get and
  • 18:41get the review team together,
  • 18:43and we plan to and then receive
  • 18:45for proposals in January and make
  • 18:48awards by March 1.
  • 18:50So what our future plans you know,
  • 18:53just some simple structural plans.
  • 18:55So we want to complete.
  • 18:56Complete and maintain the database
  • 18:58to enhance use of the samples.
  • 19:00We want to expand tissue banking
  • 19:02by disease collection side.
  • 19:04We would like to know what people want,
  • 19:08what questions people want to
  • 19:10answer and help them accrue patients
  • 19:12and samples to do this.
  • 19:14We're very we really want to
  • 19:16foster collaborations in clinical,
  • 19:17translational basic sciences.
  • 19:20And we would also like to collaborate.
  • 19:24For example,
  • 19:25was with the nurses who you know.
  • 19:27I've also shown, right?
  • 19:29There's received smaller grants,
  • 19:31but I think there's a lot of
  • 19:34opportunities for collaboration
  • 19:35across political and and science.
  • 19:37We want to build the infrastructure for
  • 19:40clinical trial, correlative studies,
  • 19:42and then inevitably,
  • 19:44there was also support programmatic
  • 19:46rose by allowing us to reduce faculties,
  • 19:49clinical load build programs.
  • 19:52And recruit outstanding physician
  • 19:55scientists and.
  • 19:57Work on executive support and then of course,
  • 20:00this is an amazing grant and support.
  • 20:03We always have to think about maintaining
  • 20:06so future funding and cost recovery.
  • 20:08And so thank you for listening
  • 20:11and we welcome suggestions, ideas,
  • 20:13support collaborations here.
  • 20:14Our emails, Twitter handle and
  • 20:16stay tuned for the website.
  • 20:20Thank you Doctor Helene that was very
  • 20:23nice presentation and I hopefully
  • 20:25everyone noted the upcoming pilot grants.
  • 20:28I just rounded on NP11 and I think
  • 20:30the nursing team talked about
  • 20:31and everyone talked about how
  • 20:33clinical trials are important too,
  • 20:35and research is important to our patients.
  • 20:38So thank you. I'm gonna leave questions
  • 20:39for the instance I want to make sure
  • 20:41we get through some of the key parts,
  • 20:43so please type your questions for Doctor
  • 20:45Helene in the chat and we can also answer.
  • 20:48But next step is Doctor Kanowitz
  • 20:50going to talk about informed.
  • 20:51Decision making with our patients.
  • 20:55Thank you for inviting me to talk
  • 20:59about our quality improvement project.
  • 21:02The population is aging and the
  • 21:06over 70 demographic is the fastest
  • 21:10growing sector of the population.
  • 21:14Older patients present with
  • 21:17unique clinical challenges.
  • 21:20The cancer and Aging Research Group
  • 21:23was founded by Doctor RT Courier in
  • 21:272006 to foster collaboration within
  • 21:31the oncology community to eradicate
  • 21:35ageism in all aspects of care and
  • 21:39research for older oncology patients.
  • 21:42Their work is sanctioned by ASCO,
  • 21:46my interest in geriatric oncology was.
  • 21:50Ignited when I heard her speak
  • 21:52at ASCO a number of years ago.
  • 21:55This group has developed validated risk
  • 21:58assessment tools for the population and
  • 22:02as of 2018 ASCO guidelines recommends
  • 22:06completing a geriatric risk assessment
  • 22:09on all patients over the age of 65.
  • 22:13Nonetheless,
  • 22:14clinical uptake remains low.
  • 22:18The literature suggests that we
  • 22:20both over and underestimate the
  • 22:22risk of chemotherapy administration.
  • 22:25About a third of the time,
  • 22:28and that means that we're both
  • 22:30over and under treating this cohort
  • 22:33of patients a third of the time.
  • 22:35One of our network quality improvement
  • 22:39projects was to have each physician
  • 22:42complete 10 risk assessments using the
  • 22:46Karg chemotherapy risk calculator in
  • 22:49patients over the age of 70 prior to
  • 22:53starting a new chemotherapy regimen,
  • 22:56and we did this during the winter
  • 22:58and spring months of 2021.
  • 23:00The 11 simple questions in the calculator.
  • 23:05Address all domains of function.
  • 23:08Our team thank you completed
  • 23:11the calculator on Go back.
  • 23:14Well, we'll get to that our team.
  • 23:20G and over who started a new regimen.
  • 23:23If the calculator was not done by one of
  • 23:26the network doctors over this timeframe,
  • 23:30there were about 350 new chemotherapy starts.
  • 23:35Our team consists of Alex Medway,
  • 23:40he's a he's doing a postdoc
  • 23:43research fellowship in geriatrics.
  • 23:45I was introduced to Alex by doctor Carrie
  • 23:48Gross from the School of Public Health.
  • 23:51Doctor Gross is actually an
  • 23:54inaugural member of Karg.
  • 23:57Alex is now thinking about
  • 23:59doing an oncology fellowship.
  • 24:02Uhm, so he can further this work.
  • 24:05Russell Lewis is part of our team.
  • 24:07He's a third year he monk fellow and
  • 24:11Paula Pike compliments the the team
  • 24:14with her endless energy and enthusiasm
  • 24:18for improving the patient experience.
  • 24:21She is our clinical program manager
  • 24:24and of course there is our mentors,
  • 24:27Jeremy and Dan,
  • 24:28and they just need first names.
  • 24:30Kind of like Oprah. And share.
  • 24:34Our team did the following.
  • 24:35We created a hyperlink to the
  • 24:38card tool in in the EHR.
  • 24:41We provided a dot phrase to simplify
  • 24:47documentation and we provided education.
  • 24:50Right now we're collecting
  • 24:52data on the clinical outcomes,
  • 24:56but we reported on the implementation
  • 24:59of the project in abstract form.
  • 25:02Next slide,
  • 25:03please.
  • 25:06The abstract was accepted at the
  • 25:112021 ASCO Quality Care Symposium
  • 25:14as a poster next site, please.
  • 25:20And this is what we've learned so far.
  • 25:23We had each physician complete
  • 25:26a brief survey regarding their
  • 25:28experience using the calculator.
  • 25:31The majority found that the tool was very
  • 25:35helpful in making treatment decisions
  • 25:37and especially helpful in discussing
  • 25:40chemotherapy toxicities and risk.
  • 25:4550% of physicians either attenuated dose
  • 25:49attenuated the treatment plan selected a
  • 25:53different regimen than originally intended,
  • 25:56or chose not to treat on the
  • 26:00basis of the Karg tool.
  • 26:02We found that for the most part it caught.
  • 26:04It took us less than five minutes
  • 26:07to complete supportive care.
  • 26:09Referrals were proactive in
  • 26:12lieu of reactive about a.
  • 26:14Third, at the time and the use of the
  • 26:18tool lead to meaningful goals of care.
  • 26:21Discussion greater than 50% of the time.
  • 26:26We anticipate that the outcomes data
  • 26:30will fuel sustainability of this project.
  • 26:34This was a brief presentation,
  • 26:36so I I think we have time for
  • 26:38for any questions or thoughts.
  • 26:42Being I'm going to leave the questions
  • 26:44for the end for all of us,
  • 26:45but I I think I already see
  • 26:47what I saw was 70% of the folks
  • 26:49finished it in less than 5 minutes.
  • 26:50So which says that it's can be adopted
  • 26:54in clinical practice, so stay tuned.
  • 26:56I suspect that a lot of people may
  • 26:58be reaching out to see how they
  • 26:59can use the calculator Next up.
  • 27:02Are you like and Jeremy one named Karen?
  • 27:07We're only going with the
  • 27:08superstars alright alright
  • 27:09we're very haunted. Trails and
  • 27:11talking yeah. Alright, let me.
  • 27:18Can you see this? Does it is, but it's
  • 27:21not. It's not
  • 27:22in it's like now you are perfect
  • 27:24OK good alright so like Jane.
  • 27:27First of all I want to
  • 27:29say that was fantastic.
  • 27:30I like by nature I like to dazzle
  • 27:32you with wonderful new programs
  • 27:34that are going to improve care,
  • 27:36delivery to our patients.
  • 27:39This presentation is not that.
  • 27:43Instead I'm going to take a book
  • 27:45out of a page out of rob forward
  • 27:47fogarty's book and talk to you.
  • 27:49About honestly and openly about
  • 27:52some of the sort of realities
  • 27:55that we're facing this week.
  • 27:57So there is a national shortage
  • 27:59of ABRAXANE due to manufacturing
  • 28:01delays at Bristol Myers Squibb.
  • 28:04This is not generated here at Yale.
  • 28:07It's a national problem and at
  • 28:09this point we don't know when this
  • 28:11situation will be resolved and the
  • 28:14supply chain will return to normal.
  • 28:16At present the supply we have
  • 28:18today and we have been our amazing
  • 28:21pharmacy team led by Sam Abdul
  • 28:24Ghani and many Merle who works on.
  • 28:27All of our sort of pharmacy
  • 28:29policy have been avidly working
  • 28:31to get as much as they can.
  • 28:33Our current supply would run out
  • 28:35in one week if we continued at
  • 28:38our current usage rate and we are
  • 28:41not expecting any large influx of
  • 28:43new vials in the next few weeks.
  • 28:46So at this time we needed to develop
  • 28:49criteria to guide the allocation
  • 28:51of our limited supply and provide
  • 28:55alternative treatment options.
  • 28:57So we pulled together a group of
  • 29:00disease team leaders and heavy ABRAXANE
  • 29:02users who have the most patients on
  • 29:05ABRAXANE across the system and came
  • 29:08up with the following guidelines.
  • 29:10So for any new patients starting treatment,
  • 29:13please choose alternative therapy and,
  • 29:17if clinically appropriate,
  • 29:19considered deferring treatment with ABRAXANE.
  • 29:21I do think it's important to point out
  • 29:25that ABRAXANE is just albumin bound.
  • 29:27Paclitaxel,
  • 29:27it is not a novel or different
  • 29:30drug for the most part.
  • 29:33So of all things to be in shortage,
  • 29:35this is one where we really
  • 29:36do have viable alternatives.
  • 29:38Currently we are going to we have
  • 29:41to restrict the ABRAXANE supply to
  • 29:44patients who have curable disease
  • 29:47and to allow them to finish the
  • 29:50treatment that they're currently
  • 29:51undergoing for all of our other
  • 29:54patients who are on non curative
  • 29:56or palliative treatment we need to
  • 29:59convert them to alternative options.
  • 30:01So far it looks like this is a little
  • 30:04bit above 50 patients across our system.
  • 30:07So for breast and
  • 30:09gynecological malignancies we.
  • 30:10Recommend using an equivalent dose
  • 30:12of paclitaxel if patients have
  • 30:15had infusion reactions to taxal.
  • 30:17Talk to your pharmacist.
  • 30:19We will have guidelines for re
  • 30:21challenging patients who have had
  • 30:23prior reactions and we have lots
  • 30:26of experience for doing this.
  • 30:28For patients who are undergoing
  • 30:30pancreatic with her patients with
  • 30:32pancreatic cancer undergoing palliative
  • 30:34treatment with gemcitabine and ABRAXANE,
  • 30:37which is often used in the second line,
  • 30:39setting options will need to
  • 30:41be individualized depending on
  • 30:43the line of therapy.
  • 30:45So options include gemcitabine
  • 30:47as a single agent.
  • 30:49Other gemcitabine based
  • 30:51combinations or modified folfirinox,
  • 30:54folfiri or folfox.
  • 30:56So gemcitabine
  • 30:58and paclitaxel has not been studied.
  • 31:01It doesn't mean it doesn't work,
  • 31:02it's just that this study
  • 31:05was done with ABRAXANE.
  • 31:06This could be an option to consider,
  • 31:08but it's important to recognize the
  • 31:11absence of any data supporting this
  • 31:13benefit or or refuting the benefit.
  • 31:16And there is some biological theory that
  • 31:18the albumin bound paclitaxel could be more
  • 31:21effective in a pancreatic population.
  • 31:24There is phase two data.
  • 31:26At least supporting safety and activity
  • 31:29of docetaxel with gemcitabine and the
  • 31:33advanced pancreatic cancer population.
  • 31:35So if you have any questions,
  • 31:37please reach out to our disease team leaders.
  • 31:40They're more than happy to talk to you
  • 31:42on a case by case basis and work with
  • 31:45your pharmacist if you are not sure.
  • 31:48Sort of what the appropriate alternative
  • 31:50regimen is for your patient.
  • 31:54The other thing that we need to talk about
  • 31:56is how we message this to our patients,
  • 31:58because this is not easy and these
  • 32:01are not easy discussions to have.
  • 32:03I wish we didn't have to have them,
  • 32:05but I think the best approach is
  • 32:07to be open and honest to tell them
  • 32:10that the shortage is a result of the
  • 32:13manufacturer delay that our priority
  • 32:15is to continue their treatment with
  • 32:17safe and proven options and that
  • 32:20we are actively working to obtain
  • 32:22an increased supply of ABRAXANE.
  • 32:25As next steps,
  • 32:26our pharmacy team is working with VMS
  • 32:29and our distributors to obtain supply.
  • 32:32It is a trickle.
  • 32:33It's not a flood and you know we we
  • 32:37will continue to communicate with
  • 32:39you as we have updates and certainly
  • 32:42let you know if we can restart.
  • 32:44Yeah, new ABRAXANE containing regiments.
  • 32:47Thank you.
  • 32:50Thank you Doctor Adelson. I think
  • 32:52this is tough decision discussions.
  • 32:54But you know, I think the messaging
  • 32:56store patient to reassure them and and
  • 32:59I I'm glad to hear that the dark teams
  • 33:01are available to answer questions.
  • 33:02So I I'm going to leave the
  • 33:04questions for the end.
  • 33:05Or if as we go along 'cause I do
  • 33:07want to have give a chance for
  • 33:09Rob to also talk about what's
  • 33:11happening with the capacity issues.
  • 33:14So I think Rob you presented
  • 33:16before on this forum,
  • 33:17but welcome back Dr Fogarty and come.
  • 33:21I don't know do you have flights
  • 33:22or are you know OK alright,
  • 33:25well floor is yours stuck for ready
  • 33:29so I everybody. I didn't prepare
  • 33:33any slides just because I there's
  • 33:36nothing left to put in type really.
  • 33:39And so I I mean, we all we've all went
  • 33:42into health care to take care of people,
  • 33:43so I'm just going to share
  • 33:45with you some stories that our
  • 33:47colleagues have shared with me.
  • 33:48Over the past couple of weeks. To try to.
  • 33:54You know, just just to show one so
  • 33:57that they felt heard because it's a
  • 33:59lot of people are really struggling.
  • 34:02And two, because there's no sugarcoating,
  • 34:05it's just really bad and continues to be bad.
  • 34:08And I've I've I've.
  • 34:11Uh, I told another group.
  • 34:13I don't know.
  • 34:13Two weeks ago that the the Canary is dead.
  • 34:17And now it is dead and cold,
  • 34:19and the winter.
  • 34:21If if what September was for us any kind
  • 34:28of prognostic factor I shared with the
  • 34:31senior leaders of the institution and
  • 34:33the health system that it is a possibility,
  • 34:36maybe not a probability,
  • 34:38but it is a possibility that we will
  • 34:41no longer function during flu season.
  • 34:43I think it's that it's that grim,
  • 34:45so some.
  • 34:47Just some stories we today.
  • 34:49The Children's Hospital.
  • 34:51The Children's Emergency room has.
  • 34:54That ten treatment based and
  • 34:57at 8:00 o'clock this morning
  • 34:59they had 14 boarded patients.
  • 35:01So that has always been an area that has
  • 35:04been protected because of what it is
  • 35:06and we were no longer able to protect it.
  • 35:10The Adult Emergency Department
  • 35:12today was a good day.
  • 35:14They only had 80 borders.
  • 35:16Uh,
  • 35:1730 of them were behavioral health,
  • 35:20which I understand is is not a
  • 35:22traditional medical surgical patient,
  • 35:24but is a patient with a disease
  • 35:26and occupies a treatment room.
  • 35:29So they had about a third of
  • 35:32their capacity staring a Thursday
  • 35:35in the fall with nice weather.
  • 35:38With the rise in interpersonal violence
  • 35:41and crime, that is a tough sell.
  • 35:45Uhm, some other emergency department.
  • 35:48In September,
  • 35:48we broke all the boarding records
  • 35:51and when it was really bad,
  • 35:53the bed managers would come in in
  • 35:55the morning and assigned beds.
  • 35:56Two patients that had been
  • 35:58waiting for 72 hours or more in
  • 36:02in the emergency departments.
  • 36:04The ER at York Street had all of
  • 36:07their resuscitation rooms occupied
  • 36:09with critically ill patients and had
  • 36:12a penetrating trauma come in and had
  • 36:15to treat that patient in the A side,
  • 36:17which is normally where you would
  • 36:20put someone who comes in with.
  • 36:22A migraine or a new?
  • 36:28Non critical abdominal pain.
  • 36:29And they did what they could,
  • 36:32and they saved that person's
  • 36:33life and it was truly remarkable.
  • 36:36We had at 1.24 ambulances in
  • 36:40our arrival bays.
  • 36:43Which is about double what we have
  • 36:45and we had 24 and all of them
  • 36:47had patients in them and the wait
  • 36:50was so long that the Ed staff
  • 36:52were going to the ambulances.
  • 36:54And performing triage diagnostic
  • 36:55workups in the back of the ambulance.
  • 37:01And I could keep going on and on,
  • 37:04but I I think that that proves the point.
  • 37:07And flu hasn't arrived yet.
  • 37:10So I'll take a moment and just share
  • 37:11with you what we know about flu,
  • 37:13which is not a lot we normally
  • 37:16pick our flu vaccine.
  • 37:17It's been picked.
  • 37:18The four strains have been picked.
  • 37:20They're growing in the eggs,
  • 37:21but I guess now they're probably in vials,
  • 37:23but but either way.
  • 37:26Australia did not have much of a flu season.
  • 37:29They still had a lot of societal lockdowns.
  • 37:33Whether or not that's something that
  • 37:35is agreed with me, that is a fact.
  • 37:38They had very aggressive lockdowns,
  • 37:40so we don't really know
  • 37:41what's going to happen,
  • 37:42but there's early data out of Australia
  • 37:45that the virus is put in the vaccine.
  • 37:48Maybe we're not a good match,
  • 37:49but the sample size was infinitesimally
  • 37:52small, so we really have no
  • 37:54idea what we're up against.
  • 37:57There were two studies in
  • 37:59pre print out of Pittsburgh.
  • 38:01That are not encouraging
  • 38:04and they invoke that.
  • 38:06One of them was very well done.
  • 38:08If anybody wants them,
  • 38:09I'm happy to send them to you.
  • 38:10Just send me an email.
  • 38:11My name's in the corner
  • 38:12or you can you can just.
  • 38:14I don't know,
  • 38:15everybody knows how to
  • 38:15get ahold me these days.
  • 38:16So one of the studies out of
  • 38:18Pittsburgh looked at historic trends.
  • 38:20When you have a a light influenza
  • 38:22season and what happens the following
  • 38:24year and there's a rebound effect
  • 38:26where the influenza tends to be more
  • 38:29severe and they extrapolated that based
  • 38:31on what we saw last year and it is,
  • 38:34it is not encouraging.
  • 38:36Of that,
  • 38:37the.
  • 38:38You know,
  • 38:38people talk about acuity and usually
  • 38:40what they're talking about is
  • 38:42this thing called casemix index,
  • 38:43and I know most of you know what that is,
  • 38:44but if there's one person who doesn't.
  • 38:47It's an adjustment based on
  • 38:49DRGS assigned to inpatients.
  • 38:51And it's a crude measure for how
  • 38:54much resource a patient needs,
  • 38:56how intensive their inpatient courses.
  • 38:59In our CMI just keeps its went up.
  • 39:02It has not gone back down and people
  • 39:04say it's edging down a little bit,
  • 39:05but it's still.
  • 39:06It's still markedly higher
  • 39:08than it was before.
  • 39:09And then the discharge side is one of the
  • 39:13reasons why I don't have any hair left.
  • 39:16The discharge process is dependent
  • 39:18on people outside of our control,
  • 39:21so sniffs are having staffing problems
  • 39:23where they have units that are closed
  • 39:25because they can't find staff.
  • 39:27AMR excuse me AMR,
  • 39:29which is our largest provider
  • 39:32of ambulance services.
  • 39:33I think three weeks ago had 200 unfilled
  • 39:36shifts over the course of a weekend.
  • 39:39And they have to they triage
  • 39:40911 in EMS calls first,
  • 39:42because those are the sickest patients.
  • 39:44So just this morning I learned of
  • 39:47three patients that Hadamar delays
  • 39:49that actually prevented their
  • 39:51discharge because AMR couldn't
  • 39:53get around and the endoscopy
  • 39:55center on the on the in the North
  • 39:57pavilion and smile has all sorts
  • 39:59of problems getting patients
  • 40:01back out. And at one point AMR actually,
  • 40:05for all of New Haven, the New Haven region
  • 40:08only had three paramedics on a shift,
  • 40:10which doesn't work right. That just.
  • 40:13That would be like having three
  • 40:15nurses for NP15. It just doesn't.
  • 40:17It just doesn't compute, so it's a real.
  • 40:20It's a real challenge.
  • 40:21We had a DME provider that's
  • 40:22going to back out of the space.
  • 40:24So now we have to find a new provider
  • 40:26for some of those DME equipment.
  • 40:28Uhm, so it is.
  • 40:29It is really an affront
  • 40:31on everywhere you turn.
  • 40:33There's a challenge.
  • 40:34But the good news is that
  • 40:36I'm I'm really trying.
  • 40:38To be more positive these days and
  • 40:40the good news is that there is
  • 40:43entire alignment like I've never
  • 40:45seen when it comes to trying to
  • 40:48fix these processes and bringing
  • 40:50the entire force of the university
  • 40:52and the medical school and the
  • 40:54health system and even our contacts
  • 40:56through the CCA and the government,
  • 40:58the state government to fix these
  • 41:00problems and to leverage where we
  • 41:01need to leverage and to not be nice
  • 41:03because this is not functional.
  • 41:05We are a public.
  • 41:06Entity that needs to provide for our
  • 41:09community and we will be unable to do that.
  • 41:12So we've talked to DPH.
  • 41:14We've talked to CCA.
  • 41:15We actually had some some conversations
  • 41:17with other hospitals in Connecticut.
  • 41:19Everybody is feeling the same thing.
  • 41:21Just last week we held the national
  • 41:23symposium with a whole bunch of
  • 41:25health systems across the country.
  • 41:27They're all feeling the same
  • 41:29thing to some degree.
  • 41:30I think we're where maybe above
  • 41:32average because that's where we live.
  • 41:35But either way,
  • 41:35I think we're we're kind of at the
  • 41:37busier side for some of our peers.
  • 41:40And there's now a coordinated
  • 41:44institutional effort.
  • 41:46Where a whole lot of people have had
  • 41:48their basically their normal day jobs
  • 41:50put on hold and they're going into that.
  • 41:52They opened up their calling the war rooms.
  • 41:54Two different war rooms are getting opened,
  • 41:56one looking at the discharge process
  • 41:57and one looking at the provision
  • 41:59of care in the inpatient setting.
  • 42:00They're just getting launched this week.
  • 42:02They'll probably probably getting
  • 42:03ahead of the messaging a little bit,
  • 42:05but I figure I'm here and you might as well.
  • 42:09It's going to be.
  • 42:10No, there are no more third rails, right?
  • 42:12If something is broken,
  • 42:13bring it up and let's try to fix it because.
  • 42:17That's that's kind of where we are.
  • 42:19As far as the near term indicators for COVID,
  • 42:22everything looks really good.
  • 42:23There are are the CDC has moved
  • 42:26Connecticut into a jurisdiction of
  • 42:29expected decreasing hospitalizations.
  • 42:31We just moved into that this week.
  • 42:33Positive ITI rate in the health system in
  • 42:35the state is hovering around 2% or so,
  • 42:37which is much better than it was even
  • 42:39a month ago. Our COVID census went up.
  • 42:42It went up from 20 something to 30,
  • 42:45something over about a week,
  • 42:46but that's manageable.
  • 42:48We can absorb that.
  • 42:49For now, and I think that's
  • 42:53just some normal variation.
  • 42:55And that's kind of the state of affairs.
  • 42:59I figured it would be easier just
  • 43:00to talk to you for a little bit.
  • 43:02Then have a whole bunch of slides.
  • 43:04But if anybody wants me to jot this
  • 43:06down and put a slide deck together,
  • 43:08I'm happy to do that.
  • 43:09And I can distribute
  • 43:10it. Thank you, rob.
  • 43:11I think you got the message.
  • 43:12I think the key,
  • 43:14as you articulated to everybody that
  • 43:16you know our health care system
  • 43:17and we are an essential service for
  • 43:19the state for many of our people.
  • 43:21So it's been stretched and you
  • 43:23gave some very vivid examples.
  • 43:25And so I think.
  • 43:26The message, but you know,
  • 43:27as the part that I'm gonna say,
  • 43:29is the Canary Canary is not dead,
  • 43:31we're resuscitating it with sort
  • 43:33of this concerted effort and Dr.
  • 43:35Fogarty mentioned some of the pieces
  • 43:37where the the supreme alignment that
  • 43:40I've seen in the last few weeks when
  • 43:43things have really just gone into this later,
  • 43:46and we have now people on
  • 43:47the school on the hospital,
  • 43:48the nursing teams and I've rounded twice
  • 43:51in the last few days at the war room,
  • 43:53and the Capacity Command center
  • 43:55Mike and I were.
  • 43:56There this afternoon,
  • 43:57Michael Holmes and the the
  • 44:00good ideas keep coming,
  • 44:02and that's what I also want to stress
  • 44:04that we need to start thinking about
  • 44:06how this is a throughput problem
  • 44:08because the patients in the emergency
  • 44:10department need our health care.
  • 44:11And that means that we have
  • 44:13to actually think about how we
  • 44:15discharge patients on time,
  • 44:17and we still have that as an
  • 44:18issue that a lot of patients stay
  • 44:20here longer than they should.
  • 44:22So there's going to be a lot of
  • 44:24talk on all of the units around
  • 44:26the length of stay and.
  • 44:27We do for discharge.
  • 44:28This afternoon we were talking
  • 44:30about early mobilization,
  • 44:31so you're gonna hear more and
  • 44:33more from the teams around.
  • 44:35Even one discharge from one unit
  • 44:37can make a huge difference if
  • 44:38you look at all our pods.
  • 44:40So again, yes, it will be hard.
  • 44:43But just like Doctor Edelson talked
  • 44:45about the ABRAXANE shortage,
  • 44:46this is just coming.
  • 44:47You know we're in the midst of
  • 44:49a pandemic still,
  • 44:49and we're seeing the the effects of that.
  • 44:52Whether it's in supply chain as
  • 44:54we heard about the chemotherapy
  • 44:55or now delayed health care.
  • 44:57And people were presenting sicker either,
  • 45:00but sickler disease or with you know,
  • 45:02mental health problems.
  • 45:03So again, part of what we are.
  • 45:05I think my ask of all of you is
  • 45:07to also take care of each other
  • 45:09as we are the folks who are taking
  • 45:11care of our patients.
  • 45:12So I do we ask that you all of the
  • 45:14teams look out for each other.
  • 45:16This is not an easy answers,
  • 45:18but these are what I do have is
  • 45:20faith in all of us,
  • 45:21in our ingenuity and thinking
  • 45:23around how we can solve problems together.
  • 45:26I've seen it over the last.
  • 45:28Sort of waves of COVID and I have
  • 45:30full faith in all of us and our
  • 45:32nursing teams and our physicians and our APS.
  • 45:35So again,
  • 45:36some of this will mean changes or
  • 45:38as Rob mentioned,
  • 45:40the third rails that we have to think smart.
  • 45:43We can't just work our way,
  • 45:44it's harder out of this.
  • 45:45So again, stay tuned.
  • 45:47The good news is the COVID
  • 45:48numbers that are real low and
  • 45:50that is really good to see.
  • 45:52And that I think we should celebrate.
  • 45:55I want to take a few minutes
  • 45:56to answer some questions so.
  • 45:58A couple in the chat gene for you,
  • 46:01one was from Paula.
  • 46:02Why do you think the clinical uptake
  • 46:05of employing a geriatric assessment
  • 46:07has been lacking in practice?
  • 46:13Just had a unmute I I think as I'm
  • 46:18cologist we've we've been taught that.
  • 46:22Uhm, palliative chemotherapy improves
  • 46:25patients quality and quantity of time,
  • 46:29and I think over the past decade we've
  • 46:32been taught that molecular profiling is the
  • 46:35future and we need to target the tumor.
  • 46:39And this is a different way of thinking,
  • 46:41because there are are a lot of ways
  • 46:44to provide palliation that don't
  • 46:47involve chemotherapy administration,
  • 46:50and we don't just have to tailor
  • 46:52our therapy to the tumor,
  • 46:54we need to tailor it to the patient.
  • 46:57So I, I think it's the world changes
  • 46:59the way we think about how we treat
  • 47:02our patients needs to change as well.
  • 47:05Indeed, remind me the tool is easily
  • 47:07accessible. How do we access the tool?
  • 47:10Right now it's in the tools
  • 47:13section of Epic and it if
  • 47:16you're going to up to date,
  • 47:18which we do on a regular basis,
  • 47:21it's in that column.
  • 47:24Perfect and and so on,
  • 47:26St to to reach out to me and I I can
  • 47:28help them walk through it. Perfect
  • 47:30I think just sometimes a lot of
  • 47:32it is not just making it your
  • 47:34workflow and I think the more we
  • 47:35disseminated make it 'cause it seemed.
  • 47:37I saw that it was less than five
  • 47:39minutes and that's the kind of easily
  • 47:41accessible tool we want Kevin this
  • 47:43and this one maybe for you here.
  • 47:46Dr Krueger, Harriet asked,
  • 47:47is there any thought to expanding
  • 47:49ECC capacity ASAP to keep some of
  • 47:51her on patients out of the hospital?
  • 47:53We need nurses,
  • 47:54physicians and extra beds in the ECC.
  • 47:56And run it around.
  • 47:57The clock will also help the Ed.
  • 48:00The short answer is yes.
  • 48:02I think we are all convinced that
  • 48:04that's the right idea and our next
  • 48:08move and we are. I will share.
  • 48:10We are in the process of working
  • 48:12with health system leadership
  • 48:14to both identify alternative
  • 48:16spaces within smilow and do
  • 48:18the necessary moves to
  • 48:21free those spaces for expansion
  • 48:24of clinical programming.
  • 48:26And I think that that will open the door
  • 48:28and then there is the staffing issue.
  • 48:31You know, I think one of the
  • 48:32things that was helpful about
  • 48:35Rob's presentation is he.
  • 48:37Very poignantly demonstrated.
  • 48:39Not only do
  • 48:40we have issues with space and
  • 48:44acuity in clinical volume,
  • 48:46but we as a health system as
  • 48:48is every other health
  • 48:49system across the country,
  • 48:50are struggling with staffing shortages.
  • 48:53So once we develop the clinical space,
  • 48:58we will also be challenged, some with
  • 49:01getting staffing to expand to provide
  • 49:04those services. And I'll say that.
  • 49:07These are things that we're working on
  • 49:09in in parallel,
  • 49:10not in series, but
  • 49:12you know, that's the work
  • 49:13we have to do to move forward,
  • 49:15and I appreciate the question.
  • 49:18Thanks Kevin, and I think Rob I.
  • 49:20To me it seems like if it
  • 49:22keeps patients out of the E D.
  • 49:23This may be an opportunity for us to sort
  • 49:25of say as part of this new thinking.
  • 49:27You know solutions that make an impact.
  • 49:29This one may be and take it to the top.
  • 49:32So this is the kind of
  • 49:33thinking we want you know.
  • 49:35Again the ideas that may have an impact
  • 49:37and assessing them if they work,
  • 49:39use them if not so again different way
  • 49:41for us to think than in the past but
  • 49:44as Rob has mentioned things have been
  • 49:45at a crisis where we have hundreds of
  • 49:48patients sitting in the Indian Head as a.
  • 49:51Huge impact on all of our services.
  • 49:55Karen, I guess a question for you.
  • 49:57While people feel more
  • 49:58comfortable asking questions,
  • 49:59do you have a sense when the shortage
  • 50:02will like nap or is that unclear for you?
  • 50:05We don't know yet.
  • 50:07And I wish I did, yeah.
  • 50:11One thing that when we talk about
  • 50:13some of the inpatient issues
  • 50:14I do think we have a culture,
  • 50:16especially in oncology of doing
  • 50:19everything a patient might need in
  • 50:22the course of their hospitalization,
  • 50:25and I'm beginning to do some work
  • 50:27on the system level with this.
  • 50:29But one thing to think about is
  • 50:32before ordering or telling your
  • 50:33house staff to order a test,
  • 50:36think about will this test help
  • 50:38get the patient home sooner.
  • 50:40Will this konsult help get
  • 50:42the patient home sooner?
  • 50:43And if the answer is no,
  • 50:45really think about doing those
  • 50:47things in the outpatient setting
  • 50:49and I know there are issues with
  • 50:51getting those things scheduled,
  • 50:52but that kind of change in
  • 50:55philosophy will shorten our length
  • 50:57of stay and will help to some
  • 50:59degree with our capacity issues.
  • 51:02I think that's a really good point.
  • 51:04I you know, as Rob mentioned,
  • 51:06we had this whole meeting
  • 51:07across the entire health system,
  • 51:09but the chairs, the leaders,
  • 51:10the hospital leaders around thinking,
  • 51:13and one of the things that Mike
  • 51:14Holmes brought up is that well,
  • 51:15consoles get asked for and people are waiting
  • 51:17for a konsult before they get discharged.
  • 51:20I guess I wonder,
  • 51:21do you really need that console
  • 51:22to wait for your discharge,
  • 51:23or is that an outpatient visit?
  • 51:25I think these are the little things that
  • 51:28every service can sort of figure out.
  • 51:30Are we putting the orders the night before?
  • 51:32Are we waiting to sort of?
  • 51:33Figure out someone is leaving,
  • 51:35you know, I think a lot of us know
  • 51:37when patients are coming for discharge,
  • 51:40and the more we can plan and also
  • 51:43encourage our patients to be around.
  • 51:45Sort of thinking around.
  • 51:46You know it's this is this is a busy place.
  • 51:49This is not a place to recover.
  • 51:51You know this isn't high acuity place
  • 51:53and we need it for the folks who are
  • 51:55the sickest so I think this this will
  • 51:57require all of us to sort of work
  • 51:59together and think of the little things.
  • 52:01It's not just one simple solution.
  • 52:04But I I'm glad to hear Karen you pointing it,
  • 52:06and I suspect Rob has other things
  • 52:08he can ask the teams that we hear
  • 52:10about you know rounding early,
  • 52:12making sure those orders are in RV
  • 52:14and they're getting all the sniff.
  • 52:16Are there fewer people who need to
  • 52:18go to sniff and one of the things
  • 52:20that happened in the war room is,
  • 52:21if we mobilize patients early
  • 52:23and start getting them surgeons.
  • 52:24I've always known that, right?
  • 52:26You get your patient walking the
  • 52:27next day that maybe they don't need
  • 52:29to go to a sniff if they have been
  • 52:31walking all the time, so again.
  • 52:33Again, all of these are little things.
  • 52:35None of this is like a home run,
  • 52:37but rob any other thoughts that we can
  • 52:39encourage our various teams to think about,
  • 52:42and then Dr Billingslea Kim Slusser.
  • 52:45Karen Adelson,
  • 52:45another skin talked to the police teams.
  • 52:48So if there are something,
  • 52:49this is our opportunity
  • 52:50to sort of bring those up
  • 52:53yet. So one of the one of the
  • 52:55things I'll point out is the.
  • 52:57And I realize I'm a hospitalist.
  • 52:58I've had 1/2 day of outpatient in
  • 53:00the past ten years, so I'm going to.
  • 53:03I'm not going to stay
  • 53:04within my swimlane here,
  • 53:05but in the inpatient setting.
  • 53:09In early September.
  • 53:11The MRI cue was something that
  • 53:15had never happened before,
  • 53:17so the when we come in in the morning,
  • 53:19the number of adults.
  • 53:20Adult MRI orders on inpatients is usually
  • 53:23around 20 or 30 for the whole house.
  • 53:26And we came in and it was 86.
  • 53:30I don't know.
  • 53:31You know they book them in 15 minute
  • 53:33increments and this is where I'm
  • 53:35starting to get out of my my swimlane,
  • 53:38but that's almost impossible to
  • 53:39accomplish with the number of
  • 53:41magnets that we have and that
  • 53:43is with wiping everything else.
  • 53:45So all of that stuff that is is
  • 53:47just kind of easy to get 'cause the
  • 53:49patient sitting there in front of you.
  • 53:51It's going to become less easy
  • 53:53to get a lot of those things so
  • 53:56I would keep an eye on that and
  • 53:59turn around times and.
  • 54:01The granular thing is if you do
  • 54:03have a patient going to a sniff.
  • 54:05Uh,
  • 54:05if if you're the if you're the
  • 54:07clinical team walking in the room,
  • 54:09you have a lot of authority with
  • 54:11with how that goes and work with
  • 54:14your case manager and and try to
  • 54:17engage in that process earlier.
  • 54:19You know,
  • 54:19go to transitions of care rounds and
  • 54:22answer those questions about medical
  • 54:24readiness and what's discharged
  • 54:25dependent if you click that.
  • 54:27If someone clicks that discharge
  • 54:29dependent button on an order.
  • 54:31It will move up in the queue
  • 54:33and it will happen,
  • 54:34but someone else will move down,
  • 54:36so it's a tool, but it's a 0 sum game
  • 54:38and if you need to do it to get someone out,
  • 54:40push that button.
  • 54:42It'll get done.
  • 54:43And the last thing I'd say is.
  • 54:46There's a, there's a.
  • 54:47There's a misperception in the community that
  • 54:50things are back to normal in the hospital.
  • 54:52We all know they're not.
  • 54:55We live it every day.
  • 54:58And that's dangerous because you don't want
  • 55:00people to not seek care when they need it.
  • 55:02But what I've what I would say,
  • 55:04and this is me, rob,
  • 55:05this is not, you know,
  • 55:06anything other than that.
  • 55:07I don't speak for anyone else.
  • 55:08I've been very open and honest when
  • 55:10people ask me in my private life,
  • 55:12how is it at the hospital?
  • 55:13And I take that opportunity to educate them.
  • 55:16And last time I was on service.
  • 55:17I did that with my patience
  • 55:18and I think it it helped.
  • 55:20It helped around the discharge
  • 55:22discussion and the sniff placements.
  • 55:25Uh, and it lowers the temperature
  • 55:26in the room for everybody.
  • 55:28In your case,
  • 55:29managers will feel heard.
  • 55:30So think about those studies if
  • 55:31you if you don't actually need it,
  • 55:34but Doctor Who just said
  • 55:35please don't do it
  • 55:36if you need to pull the trigger on that
  • 55:38discharge dependent button, do it.
  • 55:41And work early with your case managers.
  • 55:44There's nothing they love more than having
  • 55:46an attending walk in the room and say hi,
  • 55:47I'm here for transitions of care rounds.
  • 55:49You may have to brush up on your
  • 55:52syncope stabilization because they
  • 55:53just might fall into their chair.
  • 55:55Uhm, but that is a huge huge win for them.
  • 55:58They can just get all their questions
  • 56:00answered very quickly and nobody
  • 56:01knows it better than the the the
  • 56:03you know the service attending.
  • 56:06I think some really good thoughts
  • 56:08and then I think another plug for
  • 56:09the ECC and the care centers Kevin.
  • 56:11So I think folks like the idea
  • 56:13of extending in using the ECS for
  • 56:16keeping our patients out of the
  • 56:18Kelly Olino asked the same question,
  • 56:20but putting it in our network.
  • 56:22So again, I think you know I suspect
  • 56:24I don't know if it's possible,
  • 56:26but certainly sees some a lot of agreement.
  • 56:28OK Dr Helene, I think the announcements
  • 56:31for the pilot hopefully will be out soon
  • 56:33so folks can get some of those grants.
  • 56:36Thank you.
  • 56:37Or presenting that really
  • 56:39great biospecimen collection.
  • 56:41Thank you to all our panelists.
  • 56:42It's 559 and I want to wish everyone
  • 56:44a good evening and and please keep the
  • 56:47good ideas coming with your teams and
  • 56:49with Doctor Billingsley and Karen Adelson.
  • 56:51And with your floor leaders so we
  • 56:53can think about the little micro wins
  • 56:56we can to make sure that discharges
  • 56:58happen on time and so we can continue
  • 57:00to take care of all of our patients.
  • 57:02Thank you everybody.
  • 57:03Have a good evening.
  • 57:05Also, make sure to attend the
  • 57:06the the Cancer Center.
  • 57:08Director talks we had one
  • 57:09yesterday and I know Anna is making
  • 57:11sure it gets in your site.
  • 57:13So keep a lookout for next week.
  • 57:16OK take care bye bye.